uroporphyrinogen decarboxylase [Klebsiella pneumoniae subsp.

LOCUS       YP_005224516             354 aa            linear   CON 02-JUN-2020
            pneumoniae HS11286].
ACCESSION   YP_005224516
VERSION     YP_005224516.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 354)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 354)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 354)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW58914.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..354
                     /product="uroporphyrinogen decarboxylase"
                     /calculated_mol_wt=39081
     Region          10..347
                     /region_name="URO-D"
                     /note="Uroporphyrinogen decarboxylase (URO-D) is a dimeric
                     cytosolic enzyme that decarboxylates the four acetate side
                     chains of uroporphyrinogen III (uro-III) to create
                     coproporphyrinogen III, without requiring any prosthetic
                     groups or cofactors. This reaction...; cd00717"
                     /db_xref="CDD:238368"
     Site            order(26..31,36,40,46,73..79,91,96,144,154,160,207,
                     209..210,248,327)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:238368"
     Site            order(27,31,77,154,209,327)
                     /site_type="active"
                     /db_xref="CDD:238368"
     CDS             1..354
                     /locus_tag="KPHS_02160"
                     /coded_by="NC_016845.1:247145..248209"
                     /transl_table=11
                     /db_xref="GeneID:11845200"
CONTIG      join(WP_002884329.1:1..354)
ORIGIN      
        1 mtelkndryl rallrqpvdv tpvwmmrqag rylpeykatr aqagdfmslc knaelacevt
       61 lqplrrypld aailfsdilt ipdamglgly feagegprft spvkskadvd klpipdpeqe
      121 lgyvmnavrt irrelkgevp ligfsgspwt latymveggs skaftvikkm myaepqalha
      181 lldklaksvt lylnaqikag aqsvmifdtw ggvltgrdyq qfslyymhki vdgllreneg
      241 rrvpvtlftk gggqwleama etgcdalgld wttdiadarr rvgnkvalqg nmdpsmlyas
      301 aprieeevat ilagfgqgeg hvfnlghgih qdvdpehagv fveavhrlsa pyhq