adenosine kinase [Candida albicans SC5314].

LOCUS       XP_719153                347 aa            linear   PLN 18-APR-2022
ACCESSION   XP_719153
VERSION     XP_719153.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_714060.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 347)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 347)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 347)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 347)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 347)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 347)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30239.
            
            On Dec 8, 2016 this sequence version replaced XP_719153.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..347
                     /product="adenosine kinase"
                     /calculated_mol_wt=38123
     Region          9..346
                     /region_name="ribokinase_pfkB_like"
                     /note="ribokinase/pfkB superfamily: Kinases that accept a
                     wide variety of substrates, including carbohydrates and
                     aromatic small molecules, all are phosphorylated at a
                     hydroxyl group. The superfamily includes ribokinase,
                     fructokinase, ketohexokinase; cl00192"
                     /db_xref="CDD:469648"
     Site            order(11,13,15,35,60..62,65,118,129,131,133,164,195,
                     296..297,300)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:238573"
     Site            order(259,261..262,265,284,286,292,295,298..299,302,327,
                     331)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:238573"
     CDS             1..347
                     /gene="ADO1"
                     /locus_tag="CAALFM_C603080CA"
                     /coded_by="XM_714060.2:1..1044"
                     /note="Adenosine kinase; heterozygous null mutant is
                     resistant to cordycepin in C. albicans fitness test;
                     ketoconazole-induced; protein level decrease in stationary
                     phase cultures; sumoylation target; Spider biofilm
                     repressed"
                     /transl_table=12
                     /db_xref="CGD:CAL0000187548"
                     /db_xref="GeneID:3639274"
ORIGIN      
        1 mssyklvclg nplldlqakv ekdylqkydl kdndailadp khmpifeeli krddlvlvag
       61 gaaqntarga qyilppnsvv yfgsvgkdiy aerlnqanee yglttkyqiq ddiatgkcaa
      121 lihnhdrslv tdlaaanhft pdhlqkpenw eivekagfyy iggfhltvsp paikllgeha
      181 sktnkplvln fsapfiaqff kqqldevlpy vdyvianese aaayaeshdl kttdvveiak
      241 evaklpkenk qiprtviftq gleptitvty datkdsfdvq qypvkelake kvvdtngagd
      301 afaagfvasl vegkdlpqsv dvgqwaaals iqevgpsfpf pkqtysn