metalloendopeptidase [Candida albicans SC5314].

LOCUS       XP_719124               1077 aa            linear   PLN 18-APR-2022
ACCESSION   XP_719124
VERSION     XP_719124.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_714031.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 1077)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 1077)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 1077)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 1077)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 1077)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 1077)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30217.
            
            On Dec 8, 2016 this sequence version replaced XP_719124.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..1077
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..1077
                     /product="metalloendopeptidase"
                     /calculated_mol_wt=125452
     Region          37..962
                     /region_name="Ptr"
                     /note="Secreted/periplasmic Zn-dependent peptidases,
                     insulinase-like [Posttranslational modification, protein
                     turnover, chaperones]; COG1025"
                     /db_xref="CDD:440648"
     CDS             1..1077
                     /gene="STE23"
                     /locus_tag="CAALFM_C602860WA"
                     /coded_by="XM_714031.2:1..3234"
                     /note="Ortholog of S. cerevisiae Ste23 metalloprotease;
                     role in N-terminal processing of pro-a-factor to the
                     mature form; Tn mutation affects filamentous growth;
                     Spider biofilm induced"
                     /transl_table=12
                     /db_xref="CGD:CAL0000182147"
                     /db_xref="GeneID:3639236"
ORIGIN      
        1 miipslkltt trssfvsvsk yysrmsnqft ilsddktiek pllddrsyrf iklnnnglrv
       61 llindpttdk aaasldvnvg sftdkeynis glahfcehll fmgtekypke neysnylskh
      121 sgssnaytaa ehtnyyfqvg adylegaldr fsqffiaplf skscqdrein avdsenkknl
      181 qsdmwrlyql dkftsnsahp ysgfstgnyq tlhtdpvakg vdvrdilidf hkqhyssnlm
      241 slvilgkedl ntltdwaiek fsavpnkdls rpnyngelvy kpqqlgklik akpimdnhkm
      301 elnflipddl edkwdtkpng yfshlvghes kgsiiyylkq kgwatdlsag amtvcqgtsn
      361 fyiefqltpk gfenwqeiiv itfqylnfit ndepqkwiwd eieemsqvnf kfkqkmeask
      421 tvstlsnkly kfdeyipasy llssaivrkf dpeaikrfgs yftpenlrit lasqlltgln
      481 kqekwygtey eyddipqeli hqiksqpydn nqnlhyprpn hfiptnfdvt kpkskhpqva
      541 pyliehnnki nvwykqddtf evpkgsieva fhlpssntdi ntsvmsnlai emlddelnel
      601 tyfaelvglk vklhawrdgf linvsgyshk lsnllqevln nffqfkpkqd rfesikfkll
      661 knfknfgfqv pfqqvgvyhl qllndklyqq ddkiealekv tyedvyqhft qniwqsgifa
      721 evlihgnfdf aqskqirdii nesmenvkpw mekyneeqfh lqsyvlqpne tiryevplkd
      781 taninsciey yiqintntdn lklrvltdlf atiirepcfd qlrtkeqlgy vvfsgtvlgr
      841 ttlgfrvliq sertcdylqy rieeflvqfg nyinnelste dfikfkhalk nikltklkhl
      901 neetvriwsn iidgyydfds rtrqveilen itkdelveff ntfiaksdnt gklitylksq
      961 npiefteskk lhsgiinyly rnqieinhel idnlvkqyde hkdlaviake lshdinvnkd
     1021 kllkvlnksi aqpvpeiypt vklvvndkef rknrqlsgtp kpvnplskfl yndqshl