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Lys14p [Candida albicans SC5314].


LOCUS       XP_719111                592 aa            linear   PLN 18-APR-2022
ACCESSION   XP_719111
VERSION     XP_719111.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_714018.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 592)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 592)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 592)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 592)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 592)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 592)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30207.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..592
                     /product="Lys14p"
                     /calculated_mol_wt=67172
     Region          34..70
                     /region_name="GAL4"
                     /note="GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear
                     cluster DNA-binding domain; smart00066"
                     /db_xref="CDD:214501"
     Site            order(39,44..47,49,52,62)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238023"
     Site            order(40,43,50,57,60,67)
                     /site_type="other"
                     /note="Zn2+ binding site [ion binding]"
                     /db_xref="CDD:238023"
     Region          202..579
                     /region_name="fungal_TF_MHR"
                     /note="fungal transcription factor regulatory middle
                     homology region; cl23766"
                     /db_xref="CDD:419994"
     CDS             1..592
                     /gene="LYS14"
                     /locus_tag="CAALFM_C602750CA"
                     /coded_by="XM_714018.2:1..1779"
                     /note="Zn(II)2Cys6 transcription factor; has similarity to
                     S. cerevisiae Lys14, which is a transcription factor
                     involved in the regulation of lysine biosynthesis genes"
                     /transl_table=12
                     /db_xref="CGD:CAL0000176046"
                     /db_xref="GeneID:3639217"
ORIGIN      
        1 msqspsslsp atasssgvns psdqpplppr vrksysrngc reckrrkirc peekpycstc
       61 vrlgkqcsyp lagekvlris rrlikeeien mgkstqflpv qydiprrikp qtqsvikpsp
      121 lnienlinsn dflngadlnv ltadlnnlvs diievsnipi leedfqfdfl nepiiveqit
      181 knvpidyikl prkheqlywe efynnfaqii epfqaydtkt kktsnpardi ilqtaatepf
      241 llaailaega ntcylkykrp ederaygayl skclkllepa retdinanie avlltllllt
      301 aatatsqtqk wrphlmgaks lllkainqnv skkfvfckyw fvsieilagl stnlggtlqt
      361 daeidqlvtp gnefeievlr dlgiisdqgf nilmgydntc lacfrdllki lnkkrlnmyi
      421 dtmsyvklls dfynqanivy idsrgviaen eltryvpglp ieelrinnas ywiswqdish
      481 qsyvlsslim iltrffvidv sglvdkviqf ihylnqfsdv qqhaspylll miqwpllvtg
      541 lsttkleqrh lllkyfsmvg qigaaaanvs iqillkhwkg tidienddtl iy