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Cdc37p [Candida albicans SC5314].


LOCUS       XP_719095                508 aa            linear   PLN 18-APR-2022
ACCESSION   XP_719095
VERSION     XP_719095.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_714002.1
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 508)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 508)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 508)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 508)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 508)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 508)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30194.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..508
                     /product="Cdc37p"
                     /calculated_mol_wt=58433
     Region          2..201
                     /region_name="CDC37_N"
                     /note="Cdc37 N terminal kinase binding; smart01071"
                     /db_xref="CDD:198139"
     Region          260..380
                     /region_name="CDC37_M"
                     /note="Cdc37 Hsp90 binding domain; pfam08565"
                     /db_xref="CDD:430078"
     Region          412..>475
                     /region_name="CDC37_C"
                     /note="Cdc37 C terminal domain; cl07247"
                     /db_xref="CDD:447284"
     CDS             1..508
                     /gene="CDC37"
                     /locus_tag="CAALFM_C602610CA"
                     /coded_by="XM_714002.1:1..1527"
                     /note="Chaperone for Crk1p; interacts with Crk1p kinase
                     domain and with Sti1p; putative phosphorylation site at
                     Ser14; functional homolog of S. cerevisiae Cdc37p; likely
                     to be essential for growth; regulated by Gcn2p and Gcn4p"
                     /transl_table=12
                     /db_xref="CGD:CAL0000192456"
                     /db_xref="GeneID:3639210"
ORIGIN      
        1 mpidyskwdk ieisddsdve vhpnvdkqsf irwkqrdihe krmqrnieik siliqltmya
       61 klnervdyll ekltstelld sekvmsklns efdpqekfdy dklikdkgst lrkglkdlkf
      121 dreeientpc ynemiedlfv qikddhpetk tdgdklieyl kehrnriddv lskqtikldd
      181 llyqkaqliv sddlhtgfdr sflnkdkpee keenqdkpka peakkttvtt tetinspkpv
      241 eentdkeild eleilpatke fakipsdnls kaaeflikhp sicteqqkda limtafdlql
      301 enksdeakhi vhqslllqyv gqlsdngkaa panvinaikl ffskiaaess pakhafledv
      361 nqtfnhikgr ceiikeeqkq naankegtge eeeeealiql kalddntels vnipqegtke
      421 yeifttklpi efqnaiktes idevnkefak lkiedaeril eifnecgvig isgyiedeke
      481 feelkkeyah etanqeedqs asvedtvd