triglyceride lipase [Candida albicans SC5314].

LOCUS       XP_716721                597 aa            linear   PLN 18-APR-2022
ACCESSION   XP_716721
VERSION     XP_716721.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_711628.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 597)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 597)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 597)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 597)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 597)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 597)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30111.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..597
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..597
                     /product="triglyceride lipase"
                     /calculated_mol_wt=67339
     Region          198..476
                     /region_name="Lipase_3"
                     /note="Lipase (class 3). Lipases are esterases that can
                     hydrolyze long-chain acyl-triglycerides into di- and
                     monoglycerides, glycerol, and free fatty acids at a
                     water/lipid interface. A typical feature of lipases is
                     'interfacial activation,' the process of...; cd00519"
                     /db_xref="CDD:238287"
     Site            order(272..273,287..295)
                     /site_type="active"
                     /note="active site flap/lid [active]"
                     /db_xref="CDD:238287"
     Site            362..366
                     /site_type="active"
                     /note="nucleophilic elbow [active]"
                     /db_xref="CDD:238287"
     Site            order(364,419,467)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238287"
     CDS             1..597
                     /gene="ATG15"
                     /locus_tag="CAALFM_C601740CA"
                     /coded_by="XM_711628.2:1..1794"
                     /note="Putative lipase; fungal-specific (no human or
                     murine homolog); Hap43p-repressed gene"
                     /transl_table=12
                     /db_xref="CGD:CAL0000191921"
                     /db_xref="GeneID:3641641"
ORIGIN      
        1 mtleknrhan kgtswtwmiy kfvvgvitva ilvlfitqks vsqaqdklrv eqqaifsdqd
       61 tlqlkhifhh gtgpknyrlh rrlditseyl akhqpyfttl tqqlsepvle ehiasdnldk
      121 iyqqsdwpei hkgknpfsie lpfkkadsea trlkerntln fiesylnyar dikgdaqiln
      181 rinldwihde ikvpnvtdrd tvvtlatiss nayvrypkdd dekrksdwid lgdwdpnred
      241 ddvnfgwddi glrghvfvsk dnktvvigik gtsgaglpgg gsdetggndk tndnllfscc
      301 carisymwtt vcdcyektyt cnqdclekel rkedkyyqav lelyrnvtdi yppestdiwv
      361 tghslggala sllgrtfglp avafeapgem latrrlhlps ppglpqhmen iwhfgntadp
      421 iymgvcngas stcnlagyam ettchtglqc vydvvtdkgw svnllnhrih tviddiilty
      481 netapcapsp pcrdcfnwrf vahddnekde pklpnplrss skstlstktt slkssstysg
      541 stssstvtkt tqtspissas ptdqdppkkc lkrtwygwct kwgydddddd edtferk