aurora kinase [Candida albicans SC5314].

LOCUS       XP_712513                528 aa            linear   PLN 18-APR-2022
ACCESSION   XP_712513
VERSION     XP_712513.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_707420.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 528)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 528)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 528)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 528)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 528)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 528)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30167.
            
            On Dec 8, 2016 this sequence version replaced XP_712513.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..528
                     /product="aurora kinase"
                     /calculated_mol_wt=60062
     Region          241..515
                     /region_name="STKc_Aurora"
                     /note="Catalytic domain of the Serine/Threonine kinase,
                     Aurora kinase; cd14007"
                     /db_xref="CDD:270909"
     Site            order(248..252,256,269,271,303,319..322,326,328,365,367,
                     369..370,372,383,386,423..426)
                     /site_type="active"
                     /db_xref="CDD:270909"
     Site            order(248..252,256,269,271,303,320,322,326,369..370,372,
                     383)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270909"
     Site            order(252,326,328,365,367,369,386,423..426)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270909"
     Site            order(382..388,407..409,417..426)
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270909"
     CDS             1..528
                     /gene="IPL1"
                     /locus_tag="CAALFM_C602320CA"
                     /coded_by="XM_707420.2:1..1587"
                     /note="Putative Aurora kinase; Hap43-induced; induced
                     during planktonic growth; possibly an essential gene,
                     disruptants not obtained by UAU1 method"
                     /transl_table=12
                     /db_xref="CGD:CAL0000183313"
                     /db_xref="GeneID:3645876"
ORIGIN      
        1 mmlprnsphr testlaynnn nsnnnnnnng sslfqrkpla pinsefkisk pqhikptths
       61 htfttptpkt rntattttnn nnrnnhqyrn pnlntslvft ptknssssss shsssllsss
      121 pfveepenqp esnhtratsh yrttstsqyk ssankdashs litsskrkts tkqtsestnp
      181 krrttttatq ntnnnkilnp slssstirfs tvssstssst tsssssshts pkpqqqltld
      241 dfefgkilgk gklgrvycvk hkqsglifal kvmskseimn lklekslrre ieiqsnlyhi
      301 nitrlyswfh dsiniyllle ysiegelyth lkklkrfdni masnyifqit qaliflhqrg
      361 iihrdlkpen imvsldnqlk lsdfgwsvqi nqnqnqnqih nqtqtqktph qkkqkqkrlt
      421 icgtldylpp emieskshdf svdiwalgil cyellvgkpp feainrnity ekiakvdiky
      481 psnldvdaid lisklvvkdp nkrlslkevl nhnwiiknkp kwpkniyk