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hexokinase 1 [Candida albicans SC5314].


LOCUS       XP_712429                493 aa            linear   PLN 18-APR-2022
ACCESSION   XP_712429
VERSION     XP_712429.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_707336.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 493)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 493)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 493)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 493)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 493)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 493)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30374.
            
            On Dec 8, 2016 this sequence version replaced XP_712429.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..493
                     /product="hexokinase 1"
                     /calculated_mol_wt=54692
     Region          51..489
                     /region_name="ASKHA_NBD_HK"
                     /note="nucleotide-binding domain (NBD) of the hexokinase
                     (HK) domain family; cd24000"
                     /db_xref="CDD:466850"
     CDS             1..493
                     /gene="HXK1"
                     /locus_tag="CAALFM_C604580WA"
                     /coded_by="XM_707336.2:1..1482"
                     /note="N-acetylglucosamine (GlcNAc) kinase; involved in
                     GlcNAc utilization; required for wild-type hyphal growth
                     and mouse virulence; GlcNAc-induced transcript; induced by
                     alpha pheromone in SpiderM medium"
                     /transl_table=12
                     /db_xref="CGD:CAL0000186127"
                     /db_xref="GeneID:3645964"
ORIGIN      
        1 mtetsisglr gpksmyfmei vdvssqessv lssivesfts avsasnlgvy sdevlcdiks
       61 slkenspitm lpnynvsptg dehgqylvid lggstlriav vdiskphpnl srseritivv
      121 ekswiigndf kridgeffky igskineilm gqnvidvksv intgitwsfp lettdynrgk
      181 ikhvskgytv gediydkdlk mvledtlrqe ygltldvqsi lndslavysa gcfidskmkl
      241 amvlgtginm ccslkrssdi hpskmladat lfncelslfg qnlckdfatk ydiiidkrfa
      301 glshhfktfm epdpitktlf qphelmtsgr ylpeltrlvv vdlieageif qnvdhqqmyq
      361 eyggfsgeli cfvhenddyd dihdklckay gwttvglsdi vclkevvsci ikraafivan
      421 aiiaffkllg sdelggdvti gyvgsvlnyf hkyrrlivey vnsaeeakgi kvdlkliens
      481 siigaaigaa yhk