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ferroxidase [Candida albicans SC5314].


LOCUS       XP_711267                625 aa            linear   PLN 18-APR-2022
ACCESSION   XP_711267
VERSION     XP_711267.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_706175.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 625)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 625)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 625)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 625)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 625)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 625)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW29993.
            
            On Dec 8, 2016 this sequence version replaced XP_711267.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..625
                     /product="ferroxidase"
                     /calculated_mol_wt=70767
     Region          24..142
                     /region_name="CuRO_1_Fet3p"
                     /note="The first Cupredoxin domain of multicopper oxidase
                     Fet3P; cd13851"
                     /db_xref="CDD:259920"
     Site            order(37..38,40,43,45,53,83,119..124,130,132..134,137,139,
                     141)
                     /site_type="other"
                     /note="Domain 2 interface [polypeptide binding]"
                     /db_xref="CDD:259920"
     Site            order(81,83..84,86,88..92,94,96,98..101,123,125,127,
                     129..130,132)
                     /site_type="other"
                     /note="Domain 3 interface [polypeptide binding]"
                     /db_xref="CDD:259920"
     Region          155..300
                     /region_name="CuRO_2_Fet3p_like"
                     /note="The second Cupredoxin domain of multicopper oxidase
                     Fet3P; cd13877"
                     /db_xref="CDD:259945"
     Site            order(155..158,162,189,192..195,199,209,211,213,236..238,
                     253,255,292,294..295)
                     /site_type="other"
                     /note="Domain 1 interface [polypeptide binding]"
                     /db_xref="CDD:259945"
     Site            order(218,220,232..233,235..239,241..243,245,249,251..256)
                     /site_type="other"
                     /note="Domain 3 interface [polypeptide binding]"
                     /db_xref="CDD:259945"
     Region          335..499
                     /region_name="CuRO_3_Fet3p"
                     /note="The third Cupredoxin domain of multicopper oxidase
                     Fet3p; cd13899"
                     /db_xref="CDD:259966"
     Site            order(346,350,352,411,413,452..456,458,482..486,488..489)
                     /site_type="other"
                     /note="Domain 2 interface [polypeptide binding]"
                     /db_xref="CDD:259966"
     Site            order(361,364,367..369,415,417..420,455..456,473,476..478,
                     480,482,484,488,494)
                     /site_type="other"
                     /note="Domain 1 interface [polypeptide binding]"
                     /db_xref="CDD:259966"
     CDS             1..625
                     /gene="FET34"
                     /locus_tag="CAALFM_C600440CA"
                     /coded_by="XM_706175.2:1..1878"
                     /note="Multicopper ferroxidase; induced by low iron,
                     ciclopirox olamine, ketoconazole, hypoxia; alkaline
                     induced by Rim101; repressed in fluconazole-resistant
                     isolate; Sfu1, Hog1 repressed; complements S. cerevisiae
                     fet3; Spider biofilm induced"
                     /transl_table=12
                     /db_xref="CGD:CAL0000192466"
                     /db_xref="GeneID:3647131"
ORIGIN      
        1 mratltsllv sitflvslva aethtwyfkt gwvnanpdgv yerpmigfnd twplptlrvk
       61 kgdrvqlyli ngfdnlnttl hfhglfqngt nqmdgpemvt qcpippgety lynftvdqvg
      121 tywyhshtag qygdgmrgvf viddddfpyd ydedvvltvg dhyhkyssdi ipsflsrfnp
      181 tgaepipqnf lfnetrnltw kvepgktylv rivnvggfvs qylwmedhef tvvevdgiyv
      241 eknttdmlyi ttaqrysvli ntknstdkny afmqrvdtdm ldvipsdlql ngtnyivyne
      301 daslpeaydv dsldnylddf ylkplskekl lddadytitv dvqmdnlgng vnyaffnnit
      361 yttpkvptll tvlsagdaat nelvygtntn sfvlqggdvv divlnnldtg khpfhlhgha
      421 fqlierhkei pegedpvtyn atdhadwpey pmvrdtvyvr pqsyivmrfk adnpgvwffh
      481 chiewhleqg lafqliedpq giqknekitd nhkqicekvg vpwegnaaan skdylnlvge
      541 nvqvkrlptg ftakgivalv fscisaflgl aaisyygmnd ienmekrvar dldvyfdddd
      601 ddeeeeeqsi teqaatgsss spsnk