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ferroxidase [Candida albicans SC5314].


LOCUS       XP_711265                624 aa            linear   PLN 18-APR-2022
ACCESSION   XP_711265
VERSION     XP_711265.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_706173.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 624)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 624)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 624)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 624)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 624)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 624)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW29994.
            
            On Dec 8, 2016 this sequence version replaced XP_711265.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..624
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..624
                     /product="ferroxidase"
                     /calculated_mol_wt=70502
     Region          24..143
                     /region_name="CuRO_1_Fet3p"
                     /note="The first Cupredoxin domain of multicopper oxidase
                     Fet3P; cd13851"
                     /db_xref="CDD:259920"
     Site            order(37..38,40,43,45,53,83,120..125,131,133..135,138,140,
                     142)
                     /site_type="other"
                     /note="Domain 2 interface [polypeptide binding]"
                     /db_xref="CDD:259920"
     Site            order(81,83..84,86,88..92,94,96,98..101,124,126,128,
                     130..131,133)
                     /site_type="other"
                     /note="Domain 3 interface [polypeptide binding]"
                     /db_xref="CDD:259920"
     Region          154..301
                     /region_name="CuRO_2_Fet3p_like"
                     /note="The second Cupredoxin domain of multicopper oxidase
                     Fet3P; cd13877"
                     /db_xref="CDD:259945"
     Site            order(156..159,163,190,193..196,200,210,212,214,237..239,
                     254,256,293,295..296)
                     /site_type="other"
                     /note="Domain 1 interface [polypeptide binding]"
                     /db_xref="CDD:259945"
     Site            order(219,221,233..234,236..240,242..244,246,250,252..257)
                     /site_type="other"
                     /note="Domain 3 interface [polypeptide binding]"
                     /db_xref="CDD:259945"
     Region          336..500
                     /region_name="CuRO_3_Fet3p"
                     /note="The third Cupredoxin domain of multicopper oxidase
                     Fet3p; cd13899"
                     /db_xref="CDD:259966"
     Site            order(347,351,353,412,414,453..457,459,483..487,489..490)
                     /site_type="other"
                     /note="Domain 2 interface [polypeptide binding]"
                     /db_xref="CDD:259966"
     Site            order(362,365,368..370,416,418..421,456..457,474,477..479,
                     481,483,485,489,495)
                     /site_type="other"
                     /note="Domain 1 interface [polypeptide binding]"
                     /db_xref="CDD:259966"
     CDS             1..624
                     /gene="FET3"
                     /locus_tag="CAALFM_C600460CA"
                     /coded_by="XM_706173.2:1..1875"
                     /note="Multicopper oxidase; required for growth in low
                     iron and prostaglandin E2 synthesis"
                     /transl_table=12
                     /db_xref="CGD:CAL0000183587"
                     /db_xref="GeneID:3647153"
ORIGIN      
        1 mrtflssfii lttflaslia aethtwyfkt gwvdanpdgv yprkmigfnd swplptlrvk
       61 kgdrvqlyli ngfdnlnttl hfhglfvrga nqmdgpemvt qcpippgety lynftvtdqv
      121 gtywyhshtg gqygdgmrgv fiiedddfpy hydeevvltl sdhyhkysgd impafltrfn
      181 ptgaepipqn flfnetrnat wkvepgktyf vrilniggfv sqylwmedhe ftiveidgvy
      241 veknttdliy itvaqrygvl ittknstdkn yafmngvdtt mldsvpadlq vngtnyivyn
      301 essalpdayd idsyddaldd fylkplskqk lmddadytit vdvqmnvlnd ginyaffnni
      361 sykapkvptl ltvlsageaa tneliygtnt nsfvlqggdi vdivlnnfdt gkhpfhlhgh
      421 vfqlierhea vgskesavtf nvsdhaewpe ypmirdtvyv kphsymvlrf kadnpgvwff
      481 hchvdwhleq glaivliedp qaiqknekit enhkricekv gvpwegnaaa nsndyldlkg
      541 envqvkrlpt gfttkgival vfscvaaflg lftisfygmn diahvedkva rdldidleae
      601 nedeeeavvl nqnssssdsn skph