bifunctional K:H/Na:H antiporter [Candida albicans SC5314].

LOCUS       XP_711253                663 aa            linear   PLN 18-APR-2022
ACCESSION   XP_711253
VERSION     XP_711253.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_706161.1
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 663)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 663)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 663)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 663)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 663)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 663)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30005.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..663
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..663
                     /product="bifunctional K:H/Na:H antiporter"
                     /calculated_mol_wt=73167
     Region          43..>499
                     /region_name="Na_H_Exchanger"
                     /note="Sodium/hydrogen exchanger family; cl01133"
                     /db_xref="CDD:470090"
     CDS             1..663
                     /gene="NHX1"
                     /locus_tag="CAALFM_C600570CA"
                     /coded_by="XM_706161.1:1..1992"
                     /note="Protein similar to S. cerevisiae Nhx1p, which is an
                     Na+/H+ exchanger required for intracellular sequestration
                     of Na+"
                     /transl_table=12
                     /db_xref="CGD:CAL0000198193"
                     /db_xref="GeneID:3647141"
ORIGIN      
        1 mssltiyaak illkraisgd leedtpdltt pddaedsnpv eneifsswal fillfllmsa
       61 lwssyflqqr rikavhetvl sifcgmivgl iirmspghyi qdavkfnpgy ffnillppii
      121 lnsgyelhqa nffrnlgsil tfaipgtfis alvvgiilyi wtalgldnvs lefvdalavg
      181 atlsatdpvt ilsifnaykv dpklytiifg esllndaisi vmfetcqkfh gqpvrfssff
      241 qgvglflmtf tistiigifi gilvalilkh shirrypqie tclvllfayq syffsngahm
      301 sgivsllfcg itlkhyayfn msrrtqiatk yifqllaqls enfifiylgl slftevelvf
      361 kpmliivafi aicvarwsav fplsrflnff yrtrferysa gtlstsagnm inmpdeishs
      421 yqmmifwagl rgavgvalam gfsgeakwtl latvlvvvvl tvilfggtta smleilgiki
      481 gcvdesgdfs ddefdieapp rfpqqsqqsn issvanknqn iygnrrfars sklsnykdnl
      541 savnlldqeh ggvpntgnss tsnfanvndd ddddeivgsd vddfisgsis nstsninnnn
      601 drggvlgail saeehakwft rfdeevlkpv lldtlpstgq ssqnnstsnl nssgngngkr
      661 nqs