GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase

LOCUS       XP_710571                443 aa            linear   PLN 18-APR-2022
            [Candida albicans SC5314].
ACCESSION   XP_710571
VERSION     XP_710571.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_705479.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 443)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 443)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 443)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 443)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 443)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 443)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30324.
            
            On Dec 8, 2016 this sequence version replaced XP_710571.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..443
                     /product="GDP-Man:Man(1)GlcNAc(2)-PP-dolichol
                     alpha-1,3-mannosyltransferase"
                     /calculated_mol_wt=50327
     Region          8..438
                     /region_name="GT4_ALG2-like"
                     /note="alpha-1,3/1,6-mannosyltransferase ALG2 and similar
                     proteins; cd03805"
                     /db_xref="CDD:340834"
     Site            order(21,227..229,331,353)
                     /site_type="other"
                     /note="putative ADP-binding pocket [chemical binding]"
                     /db_xref="CDD:340834"
     CDS             1..443
                     /gene="ALG2"
                     /locus_tag="CAALFM_C604030WA"
                     /coded_by="XM_705479.2:1..1332"
                     /note="Putative mannosyltransferase involved in cell wall
                     mannan biosynthesis; transcription is elevated in chk1,
                     nik1, and sln1 homozygous null mutants"
                     /transl_table=12
                     /db_xref="CGD:CAL0000176395"
                     /db_xref="GeneID:3647832"
ORIGIN      
        1 mskrqenkki afihpdlgig gaerlvvdaa vglqdfghdi iiytshcdlt hcfeevssgq
       61 lkvsvhgdsl ptnlfgklhi ffailrqfyl vcwliftgti knydyfivdq lsfcipllkm
      121 fcnsncqvlf ychfpdqllv rrtsflkkly rvpfdaieey ttgssdqivv nsnftkqifh
      181 dtfkklnhid pqvvypcvdt etivdtnass nsevskffkd spfflsinrf ersknielai
      241 ksfarmnklm vtkaiksfar mnklmvtnkk prlviaggyd srvaenveyl aelstlcdel
      301 nlinftirgk limmppsvdv lflpsistql knsliqqtel llytpprehf givpleamla
      361 ktpvlainfg gpletvvnyn gnnldeatgy tetgdftkws kiimkhynld estkiklgen
      421 grnrvinkfs rkklaqsldn iln