serine/threonine-protein kinase minibrain isoform X4 [Drosophila

LOCUS       XP_070075396             746 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_070075396
VERSION     XP_070075396.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_070219295.1
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..746
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..746
                     /product="serine/threonine-protein kinase minibrain
                     isoform X4"
                     /calculated_mol_wt=81145
     Region          290..629
                     /region_name="PKc_DYRK1"
                     /note="Catalytic domain of the protein kinase,
                     Dual-specificity tYrosine-phosphorylated and -Regulated
                     Kinase 1; cd14226"
                     /db_xref="CDD:271128"
     Site            order(310..314,318,331,333,347,367,383..386,389,391..392,
                     432,434,436..437,439,452,455,464,466..469,471,508)
                     /site_type="active"
                     /db_xref="CDD:271128"
     Site            order(310..314,318,331,333,367,383..386,389,432,434,
                     436..437,439,452)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:271128"
     Site            order(347,391,432,434,455,464,466..469,471,508)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:271128"
     Site            451..471
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:271128"
     CDS             1..746
                     /gene="mnb"
                     /coded_by="XM_070219295.1:16..2256"
                     /db_xref="GeneID:108066916"
ORIGIN      
        1 mstalvywqs tnggdaidka ttadwapfvm gpppaaaapp gvvgfssfss tttsslnhhh
       61 hsnnsngssn hhnhhhpphy inylaqigcq hrvrnwptng nqeadddgdg hqiiskfqpk
      121 sawnttanva vdrvdgnllv iqkssarsea erpqhydisa ygssggsvav daaqgsgsgg
      181 grqrhaplyg rfvveedlpp thrdvmhhhs spssssevra mqaripttfr dpssgplrkl
      241 svdliktykh inevyyakkk rraqqtqgdd dssnkkerkl yndgydddnh dyiikngekf
      301 ldryeidsli gkgsfgqvvk aydheeqchv aikiiknkkp flnqaqievk llemmnrada
      361 enkyyivklk rhfmwrnhlc lvfellsynl ydllrntnfr gvslnltrkf aqqlctallf
      421 lstpelniih cdlkpenill cnpkrsaiki vdfgsscqlg qriyhyiqsr fyrspevllg
      481 iqydlaidmw slgcilvemh tgeplfsgcn evdqmnkive vlgmppkyll dqahktrkff
      541 dkivadgsyv lkknqngrky kppgsrklhd ilgvetggpg grrldepghs vsdylkfkdl
      601 ilrmldfdpk trvtpyyalq hnffkrtade atntsgagat anagaggsgs sgagggssgg
      661 gggglgtsss ggavssssaa aptaataaat aagssgsgvg ggsssstaqq qqamplplpl
      721 plplplplpl pplagasdaq chddrr