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LOCUS XP_070075126 2205 aa linear INV 09-DEC-2024 takahashii]. ACCESSION XP_070075126 VERSION XP_070075126.1 DBLINK BioProject: PRJNA1194641 DBSOURCE REFSEQ: accession XM_070219025.1 KEYWORDS RefSeq. SOURCE Drosophila takahashii ORGANISM Drosophila takahashii Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_091683) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_030179915.1-RS_2024_12 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 12/07/2024 ##Genome-Annotation-Data-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..2205 /organism="Drosophila takahashii" /strain="IR98-3 E-12201" /db_xref="taxon:29030" /chromosome="X" /sex="female" /tissue_type="Whole fly" /dev_stage="Adult fly" /collected_by="Originally obtained from EHIME-Fly" Protein 1..2205 /product="rho GTPase-activating protein 21-A isoform X1" /calculated_mol_wt=232346 Region 37..180 /region_name="PDZ_canonical" /note="canonical PDZ domain; cl49608" /db_xref="CDD:483948" Site order(49..55,130,133,162,166,169..170) /site_type="other" /note="peptide binding site [polypeptide binding]" /db_xref="CDD:467153" Region 1222..1418 /region_name="RhoGAP" /note="GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to...; cl02570" /db_xref="CDD:470621" Site order(1262,1304,1308,1376,1379..1380,1404) /site_type="other" /note="GTPase interaction site" /db_xref="CDD:239860" Site 1262 /site_type="active" /note="catalytic residue [active]" /db_xref="CDD:239860" CDS 1..2205 /gene="RhoGAP19D" /coded_by="XM_070219025.1:657..7274" /db_xref="GeneID:108068035" ORIGIN 1 mlqnsnaaaa aqaasaasav aaaaannaal aassiqpkli virrrpnqgf gftlrhfiay 61 ppeddqssat aasasvsvsg nwpqeassma gsssgssssv avagitglep tsptslppyq 121 vkametifik evqangpahy anlqtgdrvl mvnnqpiagi aystivsmik qtpsvltlhv 181 vpkecdvlqm hytsiahtpe snrltmsths psllangshk ttfpaataaa vpappqqqqq 241 qqlisypava avttsspags phsqshpnsh hapslhggsr sgsitstasg gitilshqfy 301 pqqqqqqqqq qqhrhpaltg gsssidfgdm ahglrqhqqq qqqqqqqhly qqqqhhhqfm 361 ranqppnltv lsassatntp tptptarqpk satvlsqaly agvgvgagps saggsgsgsg 421 slsggsensd lmirlresik qkeeflkspv paslsssnsa ssstngnqap qsssspaqqq 481 qqqqhffpsh tppsgvgvqv mvppprsrhq vmlkqqqqqq qhhvlgydmy ysggklvqrs 541 stapgsvshh qqqqihhhqq iqqqqqqqhr nqvminnnak yakdldyfet lqetgvtnkv 601 ferklvshms kgfdpfkpls intsamessa stsssstvts tvkkqsvlye slqqhplaky 661 hqtqhqhqta tttvdgqtss rmelhkatla natidpmpps lppvapsskf vdkppagsss 721 vatladiaes saaaivdcav vgsgnvvrry kplssssfde gkpmrrisyl ratnneadfn 781 aaeaaavaaa gggggdaaap paasssapap tpapsapapl pisipipvaa vvepqktksl 841 veehpdptyd viggtggghe fietpngled vrlsahgsrr asmssdmrss ihidaelngk 901 yvpneleafe teieikssci ngkrmseyrs wrqvkleikg dllriysgrh aksehnviel 961 dirnfkffde sldkkkylir mqskpspsga hlatlgneln ldeasaagnh dklltssgss 1021 gvneatqqqq qaatnsssal tastssstcs sggpyteilf ktkssnemkr lfgllqwkds 1081 lnyddnehqq qgkqlaepqk taasasyldd vqggggtaaa gaadssplss hsggitdhhh 1141 vsalpaaaai vaatsdsisp vmkarksssh khipdkdlgs pksknwkdll frrggsgsgt 1201 sggvshhdla spsscaakqi gsigvplrsc pmskvnacvp hlvevctniv etkglgvvgi 1261 yripgnkaai selselvntk dfqfescasd drwedvnvvs sllklfirsl pdalmpasyy 1321 infieadkkf glerivllre iveslprhpy etmkhlirhl crvsgncevn rmepknlaii 1381 fgpsiirtpn dtletavkdm khqcrivell vtqydyffeg gslpdlaevs ggtaavnaaq 1441 pqqqtqedqt smllhnlski eriterettr tsrfmpqlrr kthgkrsavn sdtysgesvl 1501 vsgssssnnt sttthtssst sssntittti stttiqqrra qrkavqsicd qalilllptp 1561 pssvslpfqs ldyakvstsa sasasstast sssckvasas asasssssst tkfssssssa 1621 ssttavavss sisstsskll sanfkkrstg gflgsrsshq ttrkasldek dsgqssgslg 1681 hslgvglnla keqqrssvdi silltdddss srlsdtgsms lttitdtlds klrnlrsgse 1741 sndengspef pknrrhtlgq plhlhsenip yadesperlf hqfcnpldap plslhlsrsc 1801 tatntigdek pskqsgsvap lppsllkaah klqhsatvpi hqgsstapts gaatpvgtpt 1861 gssgvvvvga ipsrsssssv ttltksihpr fsnylsyers saaaagggts tgsaggaase 1921 ddsegsttsd pkeklllger pspsfflery nkkrrdhrlf rsasfncrny strhmtstqp 1981 agvasgvavv vgaaccqals aatgltkdek tdmnltkkrq iqnkqnrsik rrhtvggphd 2041 ysasngscsn hahghdlaai nynhhnrhhq qqllklgsas sagggsvaaa aetttttttt 2101 ttvlrrlggt aatgqaggea svalpgsssg sssnnnnspq sdgsngngga agvpssvqpt 2161 gvtnssgsns gsssnsssns ttpagngdqv levgirikni nrgrf