disks large 1 tumor suppressor protein isoform X21 [Drosophila

LOCUS       XP_070074987             930 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_070074987
VERSION     XP_070074987.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_070218886.1
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..930
                     /product="disks large 1 tumor suppressor protein isoform
                     X21"
                     /calculated_mol_wt=99878
     Region          38..126
                     /region_name="PDZ1_Dlg1-2-4-like"
                     /note="PDZ domain 1 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06723"
                     /db_xref="CDD:467206"
     Site            order(49..55,72,75,105,109,112..113)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467206"
     Region          152..240
                     /region_name="PDZ2_Dlg1-2-4-like"
                     /note="PDZ domain 2 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06724"
                     /db_xref="CDD:467207"
     Site            order(161..167,184,187,221,225,228..229)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467207"
     Region          453..543
                     /region_name="PDZ3_Dlg1-2-4-like"
                     /note="PDZ domain 3 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06795"
                     /db_xref="CDD:467257"
     Site            order(465..471,482,485,515,519,522..523)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467257"
     Region          574..634
                     /region_name="SH3_DLG-like"
                     /note="Src Homology 3 domain of Disks large homolog
                     proteins; cd11861"
                     /db_xref="CDD:212795"
     Site            order(576,598..599)
                     /site_type="other"
                     /note="GuK domain interface [polypeptide binding]"
                     /db_xref="CDD:212795"
     Site            order(579,581,584,593,611..612,631,633..634)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212795"
     Region          739..917
                     /region_name="Guanylate_kin"
                     /note="Guanylate kinase; pfam00625"
                     /db_xref="CDD:395500"
     CDS             1..930
                     /gene="dlg1"
                     /coded_by="XM_070218886.1:694..3486"
                     /db_xref="GeneID:108066907"
ORIGIN      
        1 mttrkkkrdg ggsgggfikk vsslfnldsv ngddswlyed iqlergnsgl gfsiaggtdn
       61 phigtdtsiy itklisggaa aadgrlsind iivsvnevsv vdvphasavd alkkagnvvk
      121 lhvkrkrdta attpaagsaa gdardggpkv meidlvkggk glgfsiaggi gnqhipgdng
      181 iyvtklmdgg aaqvdgrlni gdkliavrtn gseknlenvt helavatlks itdkvtliig
      241 ktqhlttsas gggggglssg qqlsqsqsql atsqsqsqvh qqqqqhqtpm vnsqstgaln
      301 svghtvvdsp pspitpqaaa atasviasnt tvttvtatns ssklppllig ansnsninsn
      361 snsnsnsnni nnnssssstt aivataaaat ppasfynnna smpalpvesn qtnnrsqspq
      421 prqpgsryas tnvlaavppg tpravstedi treprtitiq kgpqglgfni vggedgqgiy
      481 vsfilaggpa dlgselkrgd qllsvnnvnl thatheeaaq alktsggvvt llaqyrpeey
      541 nrfeariqel kqqaalgagg sgtllrttqk rslyvralfd ydpnrddglp srglpfkhgd
      601 ilhvtnasdd ewwqarrvlg dnedeqigiv pskrrwerkm rardrsvkfq ghaaannnvd
      661 kqstldrkkk nftfsrkfpf mksrdekned gsdqepngvv sstseldins vnnnqanepq
      721 pseenvlsye avqrlsinyt rpviilgplk drinddlise ypdkfgscvp httrpkreye
      781 vdgrdyhfvs sreqmerdiq nhlfieagqy ndnlygtsva svrevaekgk hcildvsgna
      841 ikrlqvaqly pvavfikpks vdsvmemnrr mteeqakkty eraikmeqef geyftgvvqg
      901 dtieeiyskv ksmiwsqsgp tiwvpskesl