disks large 1 tumor suppressor protein isoform X20 [Drosophila

LOCUS       XP_070074986             938 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_070074986
VERSION     XP_070074986.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_070218885.1
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..938
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..938
                     /product="disks large 1 tumor suppressor protein isoform
                     X20"
                     /calculated_mol_wt=100701
     Region          46..134
                     /region_name="PDZ1_Dlg1-2-4-like"
                     /note="PDZ domain 1 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06723"
                     /db_xref="CDD:467206"
     Site            order(57..63,80,83,113,117,120..121)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467206"
     Region          160..248
                     /region_name="PDZ2_Dlg1-2-4-like"
                     /note="PDZ domain 2 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06724"
                     /db_xref="CDD:467207"
     Site            order(169..175,192,195,229,233,236..237)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467207"
     Region          461..551
                     /region_name="PDZ3_Dlg1-2-4-like"
                     /note="PDZ domain 3 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06795"
                     /db_xref="CDD:467257"
     Site            order(473..479,490,493,523,527,530..531)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467257"
     Region          582..642
                     /region_name="SH3_DLG-like"
                     /note="Src Homology 3 domain of Disks large homolog
                     proteins; cd11861"
                     /db_xref="CDD:212795"
     Site            order(584,606..607)
                     /site_type="other"
                     /note="GuK domain interface [polypeptide binding]"
                     /db_xref="CDD:212795"
     Site            order(587,589,592,601,619..620,639,641..642)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212795"
     Region          747..925
                     /region_name="Guanylate_kin"
                     /note="Guanylate kinase; pfam00625"
                     /db_xref="CDD:395500"
     CDS             1..938
                     /gene="dlg1"
                     /coded_by="XM_070218885.1:694..3510"
                     /db_xref="GeneID:108066907"
ORIGIN      
        1 mttrkkkrdg ggsgggfikk vsslfnldsl hkassakvng ddswlyediq lergnsglgf
       61 siaggtdnph igtdtsiyit klisggaaaa dgrlsindii vsvnevsvvd vphasavdal
      121 kkagnvvklh vkrkrdtaat tpaagsaagd ardggpkvme idlvkggkgl gfsiaggign
      181 qhipgdngiy vtklmdggaa qvdgrlnigd kliavrtngs eknlenvthe lavatlksit
      241 dkvtliigkt qhlttsasgg gggglssgqq lsqsqsqlat sqsqsqvhqq qqqhqtpmvn
      301 sqstgalnsv ghtvvdspps pitpqaaaat asviasnttv ttvtatnsss klpplligan
      361 snsninsnsn snsnsnninn nsssssttai vataaaatpp asfynnnasm palpvesnqt
      421 nnrsqspqpr qpgsryastn vlaavppgtp ravsteditr eprtitiqkg pqglgfnivg
      481 gedgqgiyvs filaggpadl gselkrgdql lsvnnvnlth atheeaaqal ktsggvvtll
      541 aqyrpeeynr feariqelkq qaalgaggsg tllrttqkrs lyvralfdyd pnrddglpsr
      601 glpfkhgdil hvtnasddew wqarrvlgdn edeqigivps krrwerkmra rdrsvkfqgh
      661 aaannnvdkq stldrkkknf tfsrkfpfmk srdeknedgs dqepngvvss tseldinsvn
      721 nnqanepqps eenvlsyeav qrlsinytrp viilgplkdr inddliseyp dkfgscvpht
      781 trpkreyevd grdyhfvssr eqmerdiqnh lfieagqynd nlygtsvasv revaekgkhc
      841 ildvsgnaik rlqvaqlypv avfikpksvd svmemnrrmt eeqakktyer aikmeqefge
      901 yftgvvqgdt ieeiyskvks miwsqsgpti wvpskesl