Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]
LOCUS XP_070074533 4315 aa linear INV 09-DEC-2024 protein isoform X15 [Drosophila takahashii]. ACCESSION XP_070074533 VERSION XP_070074533.1 DBLINK BioProject: PRJNA1194641 DBSOURCE REFSEQ: accession XM_070218432.1 KEYWORDS RefSeq. SOURCE Drosophila takahashii ORGANISM Drosophila takahashii Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_091683) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_030179915.1-RS_2024_12 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 12/07/2024 ##Genome-Annotation-Data-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..4315 /organism="Drosophila takahashii" /strain="IR98-3 E-12201" /db_xref="taxon:29030" /chromosome="X" /sex="female" /tissue_type="Whole fly" /dev_stage="Adult fly" /collected_by="Originally obtained from EHIME-Fly" Protein 1..4315 /product="basement membrane-specific heparan sulfate proteoglycan core protein isoform X15" /calculated_mol_wt=477077 Region 84..>169 /region_name="CCDC66" /note="Coiled-coil domain-containing protein 66; pfam15236" /db_xref="CDD:434558" Region 418..451 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(423,430,441..442) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(434,437,441,447..448) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 444..448 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 504..536 /region_name="LDLa" /note="Low-density lipoprotein receptor domain class A; smart00192" /db_xref="CDD:197566" Site order(510,518,529..530) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(522,525,529,535..536) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 532..536 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 544..579 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(549,558,569..570) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(562,565,569,575..576) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 572..576 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 589..623 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(594,602,613..614) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(606,609,613,619..620) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 616..620 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 675..710 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(680,689,700..701) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(693,696,700,706..707) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 703..707 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 797..831 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(803,811,822..823) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(815,818,822,828..829) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 825..829 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 836..871 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(841,850,861..862) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(854,857,861,867..868) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 864..868 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 886..920 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(891,899,910..911) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(903,906,910,916..917) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 913..917 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 938..971 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(943,950,961..962) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(954,957,961,967..968) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 964..968 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 981..1011 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(982,990,1001..1002) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(994,997,1001,1007..1008) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 1004..1008 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 1012..1046 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(1017,1025,1036..1037) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(1029,1032,1036,1042..1043) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 1039..1043 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 1052..1086 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(1057,1065,1076..1077) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(1069,1072,1076,1082..1083) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 1079..1083 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 1101..1169 /region_name="Ig_3" /note="Immunoglobulin domain; pfam13927" /db_xref="CDD:464046" Region 1201..1235 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(1206,1214,1225..1226) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(1218,1221,1225,1231..1232) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 1228..1232 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 1241..1275 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(1246,1254,1265..1266) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(1258,1261,1265,1271..1272) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 1268..1272 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 1284..1318 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(1289,1297,1308..1309) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(1301,1304,1308,1314..1315) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 1311..1315 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 1336..1411 /region_name="Ig" /note="Immunoglobulin domain; cl11960" /db_xref="CDD:472250" Region 1339..1343 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409353" Region 1352..1356 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409353" Region 1375..1379 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409353" Region 1389..1394 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409353" Region 1403..1406 /region_name="Ig strand G" /note="Ig strand G [structural motif]" /db_xref="CDD:409353" Region 1510..1640 /region_name="Laminin_B" /note="Laminin B (Domain IV); pfam00052" /db_xref="CDD:459652" Region 1697..1750 /region_name="Laminin_EGF" /note="Laminin EGF domain; pfam00053" /db_xref="CDD:395007" Site order(1697,1699,1711,1721,1723,1732) /site_type="active" /note="EGF-like motif [active]" /db_xref="CDD:238012" Region 1875..2011 /region_name="Laminin_B" /note="Laminin B (Domain IV); pfam00052" /db_xref="CDD:459652" Region <2012..2038 /region_name="EGF_Lam" /note="Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055" /db_xref="CDD:238012" Region 2046..2095 /region_name="EGF_Lam" /note="Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055" /db_xref="CDD:238012" Site order(2047,2049,2056,2063,2066,2075) /site_type="active" /note="EGF-like motif [active]" /db_xref="CDD:238012" Region <2132..2162 /region_name="Laminin_EGF" /note="Laminin EGF domain; pfam00053" /db_xref="CDD:395007" Region 2228..2362 /region_name="Laminin_B" /note="Laminin B (Domain IV); pfam00052" /db_xref="CDD:459652" Region 2517..2599 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 2528..2532 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409353" Region 2544..2548 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409353" Region 2563..2567 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409353" Region 2577..2582 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409353" Region 2592..2595 /region_name="Ig strand G" /note="Ig strand G [structural motif]" /db_xref="CDD:409353" Region <2626..2679 /region_name="Ig_3" /note="Immunoglobulin domain; pfam13927" /db_xref="CDD:464046" Region 2710..2793 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 2721..2725 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409353" Region 2734..2738 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409353" Region 2757..2761 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409353" Region 2771..2776 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409353" Region 2806..2886 /region_name="Ig" /note="Immunoglobulin domain; cl11960" /db_xref="CDD:472250" Region 2823..2827 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409570" Region 2836..2840 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409570" Region 2855..2859 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409570" Region 2869..2874 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409570" Region 2882..2885 /region_name="Ig strand G" /note="Ig strand G [structural motif]" /db_xref="CDD:409570" Region 2904..2980 /region_name="I-set" /note="Immunoglobulin I-set domain; pfam07679" /db_xref="CDD:400151" Region 2912..2916 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409353" Region 2925..2929 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409353" Region 2946..2950 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409353" Region 2960..2965 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409353" Region 2973..2976 /region_name="Ig strand G" /note="Ig strand G [structural motif]" /db_xref="CDD:409353" Region 2993..3080 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 3003..3007 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409353" Region 3016..3020 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409353" Region 3060..3065 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409353" Region 3205..3281 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 3214..3218 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409353" Region 3227..3231 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409353" Region 3247..3251 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409353" Region 3261..3266 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409353" Region 3293..>3360 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 3304..3308 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409353" Region 3320..3327 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409353" Region 3343..3347 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409353" Region 3437..3505 /region_name="Ig_3" /note="Immunoglobulin domain; pfam13927" /db_xref="CDD:464046" Region 3535..3601 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 3543..3547 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409353" Region 3556..3560 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409353" Region 3575..3579 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409353" Region 3589..3594 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409353" Region 3623..3770 /region_name="LamG" /note="Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110" /db_xref="CDD:238058" Region 3793..3825 /region_name="EGF" /note="EGF-like domain; pfam00008" /db_xref="CDD:394967" Region 3873..4026 /region_name="LamG" /note="Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110" /db_xref="CDD:238058" Region 4080..4112 /region_name="EGF_CA" /note="Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054" /db_xref="CDD:238011" Region 4121..4274 /region_name="LamG" /note="Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110" /db_xref="CDD:238058" CDS 1..4315 /gene="trol" /coded_by="XM_070218432.1:209..13156" /db_xref="GeneID:108055788" ORIGIN 1 mgspgsqapa iaigisngrr ghtgslllrl llvafvlnac hvpptnakqi tkskvddqdf 61 iladtqslqg svdldddeaf lippdseekl dkkftpegnw wsqglhrvrr slnsffgsdd 121 ddqekererq rqrqnnrdaa nrqkelrrqq kesqnrekql rlerqerqrl akrnnhvvfn 181 rvtdprkras dlydeneasg lneeetttyr tyfvvnepys ddykerdslq fqnlqkllde 241 dlrnffnrnf ennddeeqei hstlervdqt kdhfkirvql rvdlpssind fgskleqqln 301 vykridrlga stdgvftfte ssvykyehqy divtprvivs gqpitekpve apqefdedpi 361 evalptdeve gsgqdsgscr gdatfqcrrs gkticdemrc dgsrdcpdae deegcevcne 421 lqfkcdnkcl plnkrcdnry dcedqtdeag cqryeveesq pqpqpqpqpe pepepepepe 481 pepepepepe epitdneqpe qnsecratef rcnngdcidi rkrcdhisdc segedeneec 541 paacsgmeyq crdgtrcisl sqqcdghsdc sdaddeehcd gsgndgedcr fdefrcgtge 601 cipmrqvcdn iydcndysde vscaeeeeds vgipigrppq rpapkhdwld eldaneyhvy 661 hpsnvyelan sknpcasnqf rcattnvcip lhlrcdnfyh cndmsdekdc eqyqrrtttt 721 trrpstsarp sftftfttqg pgllerrnst tsrttagstt rateapqwpw atrptetttt 781 npittvgvas sspqssclen iefachnrdc ipiesvcdgt pdcgrseded dalckctadk 841 ykcqhgggci pktqvcdgkp qcrdrsdesa chlngrlnkt rlgvqcqenq yqcgdgscis 901 gykrcngind caddadeync iytynedyat trlkpsdcgp dqffcddlcy nrsircnghm 961 dcsdgsdeia csslsvlpcp qhqcpsgrcy sesercdrhr hcedgsdean ccyadqfrcn 1021 ngdciaesah cdgnidcsdq sdeldcggds qclpnqfrck ngqcvsstar cnkrsdcldg 1081 sdeqncanep nnsgrgtnql klktypdnqi ikesrevifr crdegpnrak vkwsrpggrp 1141 lppgftdrng rleipnirve dagayvceav gyanyipgqh vtvnlnverl nereirpdsa 1201 cteyqatcmn gecidksgic dghpdcsdgs dehscslglk cqpnqfmcsn skcvdrtwrc 1261 dgendcgdns detscdpeps dapcrydefq crsghcipks fqcdymndct dgtdeigcsv 1321 pspmtlpaps ivvmeyevle ltcvgtgvpt ptivwrlnwg hvpekcesks yggtgtlrcp 1381 nmrpqdsgay scefintrgt fypktnsivt vtpvrsdvck agffnmlark seecvqcfcf 1441 gvstncdsan lftyaiqppi lshrvvsvel spfrqivine aspgqdlltl hhgvqfrasn 1501 vhyngretpf lalpaeymgn qlksyggnlr yevryngngr pvsgpdviit gnsftlthrv 1561 rthpgqnnrv tipflpggwt kpdgrkgtre dimmilanvd nilirlgyld starevdlin 1621 ialdsagsad qglgsaslve kctcppgyvg dscescasgy vrqargpwlg hcvpftpepc 1681 pagtygnprl gvpcqecpcp hagannfasg cqqspdgdvi crcnegyagk rcehcaqgyq 1741 gnplapggvc rkipdsscnv dgtyniysng tcqckdsvig eqcdtcapks fhlnsftytg 1801 ciecfcsgvg ldcdssswyr nqvtstfgrt rvnhgfalis dymrntpvtv pvsmstqana 1861 lsfvgsaeqa gntlywslpa aflgnkltsy ggklsytlsy splpsgimsr nsapdvviks 1921 gedlrlihyr ksqvspsvan tyaveikesa wqrgdelvpn rehvlmalsn itaiyikaty 1981 ttstkeaslr svtldtatat nlgtaravev eqcrcpegyl glsceqcapg ytrdpeagiy 2041 lglcrpcecn ghskycnset gecescsdnt egfncdrcaa gyvgdatrgt sydcqyddgg 2101 yptsrppapg nqtaeclvnc qqegtagcrg yqceckrnva gdrcdqcrpg tyglsaqnpd 2161 gckecycsgl tnqcrsasly rqlipvdfis tpplitdefg dimdrdnlvp dvprnvytyk 2221 htsytpkyws lrgsvlgnql lsyggrleys livesvgrdh rgkdvvlign glkliwsrpd 2281 ghdneqeyhv rlhedeqwtv edrgsarqat radfmtvlsd lqhililatp kvptvstsis 2341 nvilessitt rapgathasd ielcqcpsgy tgtscescap lhyrdasgrc sqcpcdasnt 2401 escglvsggn vecqcrprwr gdrcreidts piieeppqic dlsrgfccsg fqfdiapnet 2461 isfndtlqiy kgnriignmt klrygcpsre tneptpepdt stddpvrtqi ivsiarpeit 2521 ilpvggsltl sctgrmrwtn spvfvnwykq gshlpegvev qggnlqlfnl qisdsgiyic 2581 qavsnetghs ftdhvsitvs qedqrspahi vdlpndvtfe eyvsneivce vegnppptvt 2641 wtrvdghada qstrtdnnrl vfdsprksde gryrcqaens lsreekyvvv yvrsnppqpp 2701 pqqdrlyitp qevngvagds fqlscqftsa aslrydwshd grslsasspr nvvvrgnvle 2761 vrdanvrdsg tytcvafdlr trrnftesar vyieqpnepg ilgdkphilt leqniiivqg 2821 edlsitceas gtpypsikwt kvqenlaenv risgnvltiy ggrsenrgly sciaenshgs 2881 dqsstsidie prerpsltid tatqkvsvgs qaslycaaqg ipeptvewvr tdgqplsprh 2941 kvqapgyvvi ddivlddsgt yecrasniag qvsglatinv qeptlvriep drqhhivtqg 3001 delslscvgs gvptpsvfws fegrdvdrmg vpegavfaqp frtntadvki frvskenegi 3061 yvchgsndag edqqyirvev qprrgdvgag gddngdvdtr qppnrpqiqp nplsnerltt 3121 elgnnvtlic nvdnvntewe rvdgtplphn aytvrntlvi vfvepqnlgq yrcngigrdg 3181 rveahvvrel vllplpritf ypnipltvel gqnldvycqv envrpedvhw ttdnnrplps 3241 svriegnvlr fasitqaaag eyrcsatnqy gsrsknarvv vkqpsgfqpv phsqvqqrqv 3301 gdsiqlrcrl ttqygdevrg niqfnwyred gsplprgvrp dsqvlqlvkl qpedegryic 3361 nsydlgsgqq lppvsidlqv lrtttqypfn rfkggvslkd tpcmvlyica avpaapqnpi 3421 ylppvapprs perilepqls lsvqssnlpa gdgttvecfs sddsypdvvw eradgaplse 3481 nvqqvgnnlv isnvastdag nyvckcktde gdlyttsykl eveeqphelk sskivyakvg 3541 gnadlqcgad edrqpsyrws rqygqlqagr slqneklsld rvqandagty vcsaqysdge 3601 tvdfpnilvv tgaipqfrqe prsymsfptl snssfkfnfe ltfrpenadg lllfngqtrg 3661 sgdyialslk dryaefrfdf ggkpllvrae eplaldewht vrvsrfkrdg yiqvddqhpv 3721 afptsqhqqi pqleliedly iggvpnwefl paeavgqqsg fvgcisrltl qgrtvelire 3781 akfkegitdc rpcaqgpcqn kgvclesqte qaytcvcqpg wtgrdcaieg tqctagvcgs 3841 grcentendm eclcplnrag drcqyneiln eqslnfksns faaygtpkvt kvnitlsvrp 3901 asledsvily taestlpsgd ylalvlrggh aellintaar ldpvvvrsae plplnrwtri 3961 eirrrlgegi lkvgdgperk akapgsdril slkthlfvgg vdrstvkinr dvnitkgfdg 4021 cisklynsqk svnllgdird aanvqncgea neidddeyem pvalpspkva enerqlmapc 4081 asdpcenggs cseqedmaic scpfgfsgkh cqnhlqlsfn asfrgdgyve lnrshfqpal 4141 eqtyshigiv fttnkpngll fwwgqeagee ytgqdfiaaa vvdgyveysm rldgeeavir 4201 nsdirvdnge rhiviakrde ntamleldqi ldtgdtrpti nkamklpgnv fvggapdvaa 4261 ftgfrykdnf ngcivvvege tvgqinlssa aingvnanvc pandeplggt eppvv