serine/threonine-protein kinase minibrain isoform X2 [Drosophila

LOCUS       XP_044252142             916 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_044252142
VERSION     XP_044252142.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_044396207.2
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..916
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..916
                     /product="serine/threonine-protein kinase minibrain
                     isoform X2"
                     /calculated_mol_wt=96356
     Region          152..491
                     /region_name="PKc_DYRK1"
                     /note="Catalytic domain of the protein kinase,
                     Dual-specificity tYrosine-phosphorylated and -Regulated
                     Kinase 1; cd14226"
                     /db_xref="CDD:271128"
     Site            order(172..176,180,193,195,209,229,245..248,251,253..254,
                     294,296,298..299,301,314,317,326,328..331,333,370)
                     /site_type="active"
                     /db_xref="CDD:271128"
     Site            order(172..176,180,193,195,229,245..248,251,294,296,
                     298..299,301,314)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:271128"
     Site            order(209,253,294,296,317,326,328..331,333,370)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:271128"
     Site            313..333
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:271128"
     CDS             1..916
                     /gene="mnb"
                     /coded_by="XM_044396207.2:1789..4539"
                     /db_xref="GeneID:108066916"
ORIGIN      
        1 myriedtnsg gvmdknkqkl saygssggsv avdaaqgsgs gggrqrhapl ygrfvveedl
       61 ppthrdvmhh hsspssssev ramqariptt frdpssgplr klsvdlikty khinevyyak
      121 kkrraqqtqg dddssnkker klyndgyddd nhdyiiknge kfldryeids ligkgsfgqv
      181 vkaydheeqc hvaikiiknk kpflnqaqie vkllemmnra daenkyyivk lkrhfmwrnh
      241 lclvfellsy nlydllrntn frgvslnltr kfaqqlctal lflstpelni ihcdlkpeni
      301 llcnpkrsai kivdfgsscq lgqriyhyiq srfyrspevl lgiqydlaid mwslgcilve
      361 mhtgeplfsg cnevdqmnki vevlgmppky lldqahktrk ffdkivadgs yvlkknqngr
      421 kykppgsrkl hdilgvetgg pggrrldepg hsvsdylkfk dlilrmldfd pktrvtpyya
      481 lqhnffkrta deatntsgag atanagaggs gssgagggss gggggglgts ssggavssss
      541 aaaptaataa ataagssgsg vgggssssta qqqqamplpl plplplplpl plpplagasd
      601 aqchgllmhs aaanamnnfs alslqpnahp ppslgnshhs snslgslnhi spgnsnsgsn
      661 snsarhnrly ghhnsssnhn sisyphamec dppqmppppp nnhggrmrvp tilqlqppss
      721 yapssvpyyg nmsssssscs sssvaaaaaa aaaaaaaaas hlmmtdssvi sataagggpn
      781 sgpnpsaaaf lfpsqpagtq lygtapasls elplpplplp lshplppmsm plqlppssss
      841 ssasssgggg iggvigpghv gqrrhisgpa saqvnaaggg gsnnssaatg aasssdasss
      901 spmvgvcvqq npvvih