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LOCUS XP_044252014 4114 aa linear INV 09-DEC-2024 protein isoform X21 [Drosophila takahashii]. ACCESSION XP_044252014 VERSION XP_044252014.1 DBLINK BioProject: PRJNA1194641 DBSOURCE REFSEQ: accession XM_044396079.1 KEYWORDS RefSeq. SOURCE Drosophila takahashii ORGANISM Drosophila takahashii Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_091683) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_030179915.1-RS_2024_12 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 12/07/2024 ##Genome-Annotation-Data-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..4114 /organism="Drosophila takahashii" /strain="IR98-3 E-12201" /db_xref="taxon:29030" /chromosome="X" /sex="female" /tissue_type="Whole fly" /dev_stage="Adult fly" /collected_by="Originally obtained from EHIME-Fly" Protein 1..4114 /product="basement membrane-specific heparan sulfate proteoglycan core protein isoform X21" /calculated_mol_wt=454834 Region 84..>169 /region_name="CCDC66" /note="Coiled-coil domain-containing protein 66; pfam15236" /db_xref="CDD:434558" Region 385..415 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(385,394,405..406) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(398,401,405,411..412) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 408..412 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 418..451 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(423,430,441..442) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(434,437,441,447..448) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 444..448 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 504..536 /region_name="LDLa" /note="Low-density lipoprotein receptor domain class A; smart00192" /db_xref="CDD:197566" Site order(510,518,529..530) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(522,525,529,535..536) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 532..536 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 544..579 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(549,558,569..570) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(562,565,569,575..576) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 572..576 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 589..623 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(594,602,613..614) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(606,609,613,619..620) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 616..620 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 675..710 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(680,689,700..701) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(693,696,700,706..707) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 703..707 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 799..832 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(804,811,822..823) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(815,818,822,828..829) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 825..829 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 842..872 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(843,851,862..863) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(855,858,862,868..869) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 865..869 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 873..907 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(878,886,897..898) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(890,893,897,903..904) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 900..904 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 913..947 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(918,926,937..938) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(930,933,937,943..944) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 940..944 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 962..1030 /region_name="Ig_3" /note="Immunoglobulin domain; pfam13927" /db_xref="CDD:464046" Region 1062..1096 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(1067,1075,1086..1087) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(1079,1082,1086,1092..1093) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 1089..1093 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 1102..1136 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(1107,1115,1126..1127) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(1119,1122,1126,1132..1133) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 1129..1133 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 1145..1179 /region_name="LDLa" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112" /db_xref="CDD:238060" Site order(1150,1158,1169..1170) /site_type="active" /note="putative binding surface [active]" /db_xref="CDD:238060" Site order(1162,1165,1169,1175..1176) /site_type="other" /note="calcium-binding site [ion binding]" /db_xref="CDD:238060" Site 1172..1176 /site_type="other" /note="D-X-S-D-E motif" /db_xref="CDD:238060" Region 1197..1272 /region_name="Ig" /note="Immunoglobulin domain; cl11960" /db_xref="CDD:472250" Region 1200..1204 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:143220" Region 1213..1217 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:143220" Region 1236..1240 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:143220" Region 1250..1255 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:143220" Region 1264..1267 /region_name="Ig strand G" /note="Ig strand G [structural motif]" /db_xref="CDD:143220" Region 1371..1501 /region_name="Laminin_B" /note="Laminin B (Domain IV); pfam00052" /db_xref="CDD:459652" Region 1558..1611 /region_name="Laminin_EGF" /note="Laminin EGF domain; pfam00053" /db_xref="CDD:395007" Site order(1558,1560,1572,1582,1584,1593) /site_type="active" /note="EGF-like motif [active]" /db_xref="CDD:238012" Region 1618..1655 /region_name="EGF_Lam" /note="Laminin-type epidermal growth factor-like domai; smart00180" /db_xref="CDD:214543" Region 1736..1872 /region_name="Laminin_B" /note="Laminin B (Domain IV); pfam00052" /db_xref="CDD:459652" Region <1873..1899 /region_name="EGF_Lam" /note="Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055" /db_xref="CDD:238012" Region 1907..1956 /region_name="EGF_Lam" /note="Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055" /db_xref="CDD:238012" Site order(1908,1910,1917,1924,1927,1936) /site_type="active" /note="EGF-like motif [active]" /db_xref="CDD:238012" Region <1993..2023 /region_name="Laminin_EGF" /note="Laminin EGF domain; pfam00053" /db_xref="CDD:395007" Region 2089..2223 /region_name="Laminin_B" /note="Laminin B (Domain IV); pfam00052" /db_xref="CDD:459652" Region 2316..2398 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 2327..2331 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409353" Region 2343..2347 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409353" Region 2362..2366 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409353" Region 2376..2381 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409353" Region 2391..2394 /region_name="Ig strand G" /note="Ig strand G [structural motif]" /db_xref="CDD:409353" Region <2425..2478 /region_name="Ig_3" /note="Immunoglobulin domain; pfam13927" /db_xref="CDD:464046" Region 2509..2592 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 2520..2524 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409544" Region 2533..2537 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409544" Region 2556..2560 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409544" Region 2570..2575 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409544" Region 2605..2685 /region_name="Ig" /note="Immunoglobulin domain; cl11960" /db_xref="CDD:472250" Region 2622..2626 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409570" Region 2635..2639 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409570" Region 2654..2658 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409570" Region 2668..2673 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409570" Region 2681..2684 /region_name="Ig strand G" /note="Ig strand G [structural motif]" /db_xref="CDD:409570" Region 2703..2779 /region_name="I-set" /note="Immunoglobulin I-set domain; pfam07679" /db_xref="CDD:400151" Region 2711..2715 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409544" Region 2724..2728 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409544" Region 2745..2749 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409544" Region 2759..2764 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409544" Region 2772..2775 /region_name="Ig strand G" /note="Ig strand G [structural motif]" /db_xref="CDD:409544" Region 2792..2879 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 2802..2806 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409548" Region 2815..2819 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409548" Region 2859..2864 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409548" Region 3004..3080 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 3013..3017 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409541" Region 3026..3030 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409541" Region 3046..3050 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409541" Region 3060..3065 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409541" Region 3092..>3159 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 3103..3107 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409390" Region 3119..3126 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409390" Region 3142..3146 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409390" Region 3236..3304 /region_name="Ig_3" /note="Immunoglobulin domain; pfam13927" /db_xref="CDD:464046" Region 3334..3400 /region_name="IG_like" /note="Immunoglobulin like; smart00410" /db_xref="CDD:214653" Region 3342..3346 /region_name="Ig strand B" /note="Ig strand B [structural motif]" /db_xref="CDD:409390" Region 3355..3359 /region_name="Ig strand C" /note="Ig strand C [structural motif]" /db_xref="CDD:409390" Region 3374..3378 /region_name="Ig strand E" /note="Ig strand E [structural motif]" /db_xref="CDD:409390" Region 3388..3393 /region_name="Ig strand F" /note="Ig strand F [structural motif]" /db_xref="CDD:409390" Region 3422..3569 /region_name="LamG" /note="Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110" /db_xref="CDD:238058" Region 3592..3624 /region_name="EGF" /note="EGF-like domain; pfam00008" /db_xref="CDD:394967" Region 3672..3825 /region_name="LamG" /note="Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110" /db_xref="CDD:238058" Region 3879..3911 /region_name="EGF_CA" /note="Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054" /db_xref="CDD:238011" Region 3920..4073 /region_name="LamG" /note="Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110" /db_xref="CDD:238058" CDS 1..4114 /gene="trol" /coded_by="XM_044396079.1:209..12553" /db_xref="GeneID:108055788" ORIGIN 1 mgspgsqapa iaigisngrr ghtgslllrl llvafvlnac hvpptnakqi tkskvddqdf 61 iladtqslqg svdldddeaf lippdseekl dkkftpegnw wsqglhrvrr slnsffgsdd 121 ddqekererq rqrqnnrdaa nrqkelrrqq kesqnrekql rlerqerqrl akrnnhvvfn 181 rvtdprkras dlydeneasg lneeetttyr tyfvvnepys ddykerdslq fqnlqkllde 241 dlrnffnrnf ennddeeqei hstlervdqt kdhfkirvql rvdlpssind fgskleqqln 301 vykridrlga stdgvftfte ssvykyehqy divtprvivs gqpitekpve apqefdedpi 361 evalptdeve gsgqdsgscr gdatfqcrrs gkticdemrc dgsrdcpdae deegcevcne 421 lqfkcdnkcl plnkrcdnry dcedqtdeag cqryeveesq pqpqpqpqpe pepepepepe 481 pepepepepe epitdneqpe qnsecratef rcnngdcidi rkrcdhisdc segedeneec 541 paacsgmeyq crdgtrcisl sqqcdghsdc sdaddeehcd gsgndgedcr fdefrcgtge 601 cipmrqvcdn iydcndysde vscaeeeeds vgipigrppq rpapkhdwld eldaneyhvy 661 hpsnvyelan sknpcasnqf rcattnvcip lhlrcdnfyh cndmsdekdc eqyqrrtttt 721 trrpstsarp sftftfttqg pgllerrnst tsrttagstt rateapqwpw atrptetttt 781 npittvgvat ttrlkpsdcg pdqffcddlc ynrsircngh mdcsdgsdei acsslsvlpc 841 pqhqcpsgrc ysesercdrh rhcedgsdea nccyadqfrc nngdciaesa hcdgnidcsd 901 qsdeldcggd sqclpnqfrc kngqcvssta rcnkrsdcld gsdeqncane pnnsgrgtnq 961 lklktypdnq iikesrevif rcrdegpnra kvkwsrpggr plppgftdrn grleipnirv 1021 edagayvcea vgyanyipgq hvtvnlnver lnereirpds acteyqatcm ngecidksgi 1081 cdghpdcsdg sdehscslgl kcqpnqfmcs nskcvdrtwr cdgendcgdn sdetscdpep 1141 sdapcrydef qcrsghcipk sfqcdymndc tdgtdeigcs vpspmtlpap sivvmeyevl 1201 eltcvgtgvp tptivwrlnw ghvpekcesk syggtgtlrc pnmrpqdsga yscefintrg 1261 tfypktnsiv tvtpvrsdvc kagffnmlar kseecvqcfc fgvstncdsa nlftyaiqpp 1321 ilshrvvsve lspfrqivin easpgqdllt lhhgvqfras nvhyngretp flalpaeymg 1381 nqlksyggnl ryevryngng rpvsgpdvii tgnsftlthr vrthpgqnnr vtipflpggw 1441 tkpdgrkgtr edimmilanv dnilirlgyl dstarevdli nialdsagsa dqglgsaslv 1501 ekctcppgyv gdscescasg yvrqargpwl ghcvpftpep cpagtygnpr lgvpcqecpc 1561 phagannfas gcqqspdgdv icrcnegyag krcehcaqgy qgnplapggv crkipdsscn 1621 vdgtyniysn gtcqckdsvi geqcdtcapk sfhlnsftyt gciecfcsgv gldcdssswy 1681 rnqvtstfgr trvnhgfali sdymrntpvt vpvsmstqan alsfvgsaeq agntlywslp 1741 aaflgnklts yggklsytls ysplpsgims rnsapdvvik sgedlrlihy rksqvspsva 1801 ntyaveikes awqrgdelvp nrehvlmals nitaiyikat yttstkeasl rsvtldtata 1861 tnlgtarave veqcrcpegy lglsceqcap gytrdpeagi ylglcrpcec nghskycnse 1921 tgecescsdn tegfncdrca agyvgdatrg tsydcqyddg gyptsrppap gnqtaeclvn 1981 cqqegtagcr gyqceckrnv agdrcdqcrp gtyglsaqnp dgckecycsg ltnqcrsasl 2041 yrqlipvdfi stpplitdef gdimdrdnlv pdvprnvyty khtsytpkyw slrgsvlgnq 2101 llsyggrley slivesvgrd hrgkdvvlig nglkliwsrp dghdneqeyh vrlhedeqwt 2161 vedrgsarqa tradfmtvls dlqhililat pkvptvstsi snvilessit trapgathas 2221 dielcqcpsg ytgtscesca plhyrdasgr csqcpcdasn tescglvsgg nvecqcrprw 2281 rgdrcreiet neptpepdts tddpvrtqii vsiarpeiti lpvggsltls ctgrmrwtns 2341 pvfvnwykqg shlpegvevq ggnlqlfnlq isdsgiyicq avsnetghsf tdhvsitvsq 2401 edqrspahiv dlpndvtfee yvsneivcev egnppptvtw trvdghadaq strtdnnrlv 2461 fdsprksdeg ryrcqaensl sreekyvvvy vrsnppqppp qqdrlyitpq evngvagdsf 2521 qlscqftsaa slrydwshdg rslsassprn vvvrgnvlev rdanvrdsgt ytcvafdlrt 2581 rrnftesarv yieqpnepgi lgdkphiltl eqniiivqge dlsitceasg tpypsikwtk 2641 vqenlaenvr isgnvltiyg grsenrglys ciaenshgsd qsstsidiep rerpsltidt 2701 atqkvsvgsq aslycaaqgi peptvewvrt dgqplsprhk vqapgyvvid divlddsgty 2761 ecrasniagq vsglatinvq eptlvriepd rqhhivtqgd elslscvgsg vptpsvfwsf 2821 egrdvdrmgv pegavfaqpf rtntadvkif rvskenegiy vchgsndage dqqyirvevq 2881 prrgdvgagg ddngdvdtrq ppnrpqiqpn plsnerltte lgnnvtlicn vdnvntewer 2941 vdgtplphna ytvrntlviv fvepqnlgqy rcngigrdgr veahvvrelv llplpritfy 3001 pnipltvelg qnldvycqve nvrpedvhwt tdnnrplpss vriegnvlrf asitqaaage 3061 yrcsatnqyg srsknarvvv kqpsgfqpvp hsqvqqrqvg dsiqlrcrlt tqygdevrgn 3121 iqfnwyredg splprgvrpd sqvlqlvklq pedegryicn sydlgsgqql ppvsidlqvl 3181 rtttqypfnr fkggvslkdt pcmvlyicaa vpaapqnpiy 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