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LOCUS XP_022220053 595 aa linear INV 14-MAY-2021 ACCESSION XP_022220053 VERSION XP_022220053.2 DBLINK BioProject: PRJNA728747 DBSOURCE REFSEQ: accession XM_022364361.2 KEYWORDS RefSeq. SOURCE Drosophila obscura ORGANISM Drosophila obscura Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_024542752.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 14, 2021 this sequence version replaced XP_022220053.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Drosophila obscura Annotation Release 101 Annotation Version :: 101 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.6 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..595 /organism="Drosophila obscura" /isolate="BZ-5 IFL" /db_xref="taxon:7282" /chromosome="Unknown" /sex="male" /tissue_type="whole fly" /dev_stage="Adult fly" /geo_loc_name="Serbia: Babin Zub" /collection_date="2017" Protein 1..595 /product="protein kinase shaggy isoform X4" /calculated_mol_wt=60767 Region 50..359 /region_name="STKc_GSK3" /note="The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3; cd14137" /db_xref="CDD:271039" Site order(60..64,68,81,83,94,108,148..151,154,156..157,197, 199,201..202,204,216,219,230,232..235,237,275) /site_type="active" /db_xref="CDD:271039" Site order(60..63,68,81,83,108,148..151,154,199,201..202,204, 216) /site_type="other" /note="ATP binding site [chemical binding]" /db_xref="CDD:271039" Site order(64..65,228..236,244..245,276..280,282..283,287, 307..310) /site_type="other" /note="dimer interface [polypeptide binding]" /db_xref="CDD:271039" Site order(94,156,197,199,219,230,232..235,237,275) /site_type="other" /note="polypeptide substrate binding site [polypeptide binding]" /db_xref="CDD:271039" Site order(215..225,227..237) /site_type="other" /note="activation loop (A-loop)" /db_xref="CDD:271039" Site order(244,279..280,282..283,286..287,307..312) /site_type="other" /note="axin binding site [polypeptide binding]" /db_xref="CDD:271039" CDS 1..595 /gene="LOC111072462" /coded_by="XM_022364361.2:750..2537" /db_xref="GeneID:111072462" ORIGIN 1 msgrprtssf aegnkqspsl vlggvktcsr dgskittvva tpgqgtdrvq evsytdtkvi 61 gngsfgvvfq aklcdtgelv aikkvlqdrr fknrelqimr klehcnivkl lyffyssgek 121 laefpidlgi fasvlkpqrd evflnlvley ipetvykvar qyaktkqtip infirlymyq 181 lfrslayihs lgichrdikp qnllldpeta vlklcdfgsa kqllhgepnv syicsryyra 241 pelifgainy ttkidvwsag cvlaelllgq pifpgdsgvd qlvevikvlg tptreqirem 301 npnytefkfp qikshpwqkv frirtpteai nlvsllleyt psaritplka cahpffdelr 361 megnhtlpng rdmpplfnft dhelsiqpsl vpqllpkhla trssgggpaa agavsgstsv 421 sstgsgasad gaaqaqvggt agssaagsgs gsgaaaaaaa aggpatgsna ggqgnnsnpg 481 sgapsavaaa paaqqanagg aaaagggggg ggaagaataa gsvaatnagg anvtgsqsns 541 alnssstang ngsgngeaaa gggasgsaag gdengataaa aagaeteaea aavsg