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endothelial lipase [Drosophila takahashii].


LOCUS       XP_017012852             403 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017012852
VERSION     XP_017012852.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017157363.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017012852.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..403
                     /product="endothelial lipase"
                     /calculated_mol_wt=45123
     Region          67..341
                     /region_name="Pancreat_lipase_like"
                     /note="Pancreatic lipase-like enzymes. Lipases are
                     esterases that can hydrolyze long-chain acyl-triglycerides
                     into di- and monoglycerides, glycerol, and free fatty
                     acids at a water/lipid interface. A typical feature of
                     lipases is 'interfacial activation,' the...; cd00707"
                     /db_xref="CDD:238363"
     Site            178..182
                     /site_type="active"
                     /note="nucleophilic elbow [active]"
                     /db_xref="CDD:238363"
     Site            order(180,204,282)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238363"
     Site            order(263..264,279..280)
                     /site_type="active"
                     /note="active site flap/lid"
                     /db_xref="CDD:238363"
     CDS             1..403
                     /gene="LOC108068022"
                     /coded_by="XM_017157363.3:182..1393"
                     /db_xref="GeneID:108068022"
ORIGIN      
        1 mpghvthrll lgcllcllgd vpriealhrw spmmkafryl qetmlrnsle rahlnhgivf
       61 ecrtisakdf gnevhfnlql gdlrgfrrld pnkklalflh gwndqgskdw vqellltwtl
      121 fdanynvcvv dwgnlsqndy ksasmsifdv gltvagiima leelrpahfn rsnvtlagys
      181 lgahaagyag avlegrveqi igldpagplf slpaevapky rldpgdaqfv qvlhtsggsl
      241 gtslkcghad fypnggrapq tnckmfanlr dmqntnpiac shsaaaiffr qsmdpeypfv
      301 gyecgsyref aggycdgnrk arfgihsqrr aqgsfyfrta pqqpyvqrrp tnwlsgvgrm
      361 aadgggggva rnplvlrlwt nswrrrerar erqrrererd rca