disks large 1 tumor suppressor protein isoform X15 [Drosophila

LOCUS       XP_017011150             976 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_017011150
VERSION     XP_017011150.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017155661.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017011150.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..976
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..976
                     /product="disks large 1 tumor suppressor protein isoform
                     X15"
                     /calculated_mol_wt=107518
     Region          6..64
                     /region_name="L27_1"
                     /note="pfam09058"
                     /db_xref="CDD:462665"
     Region          220..308
                     /region_name="PDZ1_Dlg1-2-4-like"
                     /note="PDZ domain 1 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06723"
                     /db_xref="CDD:467206"
     Site            order(231..237,254,257,287,291,294..295)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467206"
     Region          334..422
                     /region_name="PDZ2_Dlg1-2-4-like"
                     /note="PDZ domain 2 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06724"
                     /db_xref="CDD:467207"
     Site            order(343..349,366,369,403,407,410..411)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467207"
     Region          509..599
                     /region_name="PDZ3_Dlg1-2-4-like"
                     /note="PDZ domain 3 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06795"
                     /db_xref="CDD:467257"
     Site            order(521..527,538,541,571,575,578..579)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467257"
     Region          630..690
                     /region_name="SH3_DLG-like"
                     /note="Src Homology 3 domain of Disks large homolog
                     proteins; cd11861"
                     /db_xref="CDD:212795"
     Site            order(632,654..655)
                     /site_type="other"
                     /note="GuK domain interface [polypeptide binding]"
                     /db_xref="CDD:212795"
     Site            order(635,637,640,649,667..668,687,689..690)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212795"
     Region          785..963
                     /region_name="Guanylate_kin"
                     /note="Guanylate kinase; pfam00625"
                     /db_xref="CDD:395500"
     CDS             1..976
                     /gene="dlg1"
                     /coded_by="XM_017155661.3:654..3584"
                     /db_xref="GeneID:108066907"
ORIGIN      
        1 mpvkkqeahr alelledyha rlsepqdral riaierviri fksrlfqall diqefyeltl
       61 lddsksiqqk taetlqiatk wekdgqavki adfiktsnln rncayefnnd assnqtnqsa
      121 nqlnqnqian nvsaqaqaea lsrtfksele eilnqrmrie sdtenakepp aeqqqqrssr
      181 spqqnpqqqq pqqqqqpqqq lgsksrsgsq tvngddswly ediqlergns glgfsiaggt
      241 dnphigtdts iyitklisgg aaaadgrlsi ndiivsvnev svvdvphasa vdalkkagnv
      301 vklhvkrkrd taattpaags aagdardggp kvmeidlvkg gkglgfsiag gignqhipgd
      361 ngiyvtklmd ggaaqvdgrl nigdkliavr tngseknlen vthelavatl ksitdkvtli
      421 igktqhltts asggggggls sgqqlsqsqs qlatsqsqsq vhqqqqqhqt pmvnsqstep
      481 gsryastnvl aavppgtpra vsteditrep rtitiqkgpq glgfnivgge dgqgiyvsfi
      541 laggpadlgs elkrgdqlls vnnvnlthat heeaaqalkt sggvvtllaq yrpeeynrfe
      601 ariqelkqqa algaggsgtl lrttqkrsly vralfdydpn rddglpsrgl pfkhgdilhv
      661 tnasddewwq arrvlgdned eqigivpskr rwerkmrard rsvkfqghaa annnvdkqst
      721 ldrkkknftf srkfpfmksr deknedgsdq epfmlcytqd danaegasee nvlsyeavqr
      781 lsinytrpvi ilgplkdrin ddliseypdk fgscvphttr pkreyevdgr dyhfvssreq
      841 merdiqnhlf ieagqyndnl ygtsvasvre vaekgkhcil dvsgnaikrl qvaqlypvav
      901 fikpksvdsv memnrrmtee qakktyerai kmeqefgeyf tgvvqgdtie eiyskvksmi
      961 wsqsgptiwv pskesl