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protein kinase shaggy isoform X5 [Drosophila takahashii].


LOCUS       XP_017006527             591 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017006527
VERSION     XP_017006527.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017151038.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..591
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..591
                     /product="protein kinase shaggy isoform X5"
                     /calculated_mol_wt=59846
     Region          50..341
                     /region_name="STKc_GSK3"
                     /note="The catalytic domain of the Serine/Threonine
                     Kinase, Glycogen Synthase Kinase 3; cd14137"
                     /db_xref="CDD:271039"
     Site            order(60..64,68,81,83,94,108,130..133,136,138..139,179,
                     181,183..184,186,198,201,212,214..217,219,257)
                     /site_type="active"
                     /db_xref="CDD:271039"
     Site            order(60..63,68,81,83,108,130..133,136,181,183..184,186,
                     198)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:271039"
     Site            order(64..65,210..218,226..227,258..262,264..265,269,
                     289..292)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:271039"
     Site            order(94,138,179,181,201,212,214..217,219,257)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:271039"
     Site            order(197..207,209..219)
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:271039"
     Site            order(226,261..262,264..265,268..269,289..294)
                     /site_type="other"
                     /note="axin binding site [polypeptide binding]"
                     /db_xref="CDD:271039"
     CDS             1..591
                     /gene="sgg"
                     /coded_by="XM_017151038.3:568..2343"
                     /db_xref="GeneID:108063823"
ORIGIN      
        1 msgrprtssf aegnkqspsl vlggvktcsr dgskittvva tpgqgtdrvq evsytdtkvi
       61 gngsfgvvfq aklcdtgelv aikkvlqdrr fknrelqimr klehcnivkl lyffyssgek
      121 rdevflnlvl eyipetvykv arqyaktkqt ipinfirlym yqlfrslayi hslgichrdi
      181 kpqnllldpe tavlklcdfg sakqllhgep nvsyicsryy rapelifgai nyttkidvws
      241 agcvlaelll gqpifpgdsg vdqlvevikv lgtptreqir emnpnytefk fpqikshpwq
      301 kvfrirtpte ainlvsllle ytpsaritpl kacahpffde lrmegnhtlp ngrempplfn
      361 ftehelsiqp slvpqllpkh lqnasgpgga nrssaggaas aaasgstsvs stgsgasaeg
      421 saaqqpqaqg taaaaaagsg sgsgsgsgga aaaggsgsgn nssgggasga psaavaagan
      481 aavagggggg gvgaaataat aagamaatna gganvtgsqs nsalnssgsg gsgngsgngn
      541 gngeaavsas gsggnggngg nggdndagds gaagsggsgg gaaeteaaas g