moesin/ezrin/radixin homolog 2 [Drosophila takahashii].

LOCUS       XP_016993985             632 aa            linear   INV 09-DEC-2024
ACCESSION   XP_016993985
VERSION     XP_016993985.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017138496.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..632
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..632
                     /product="moesin/ezrin/radixin homolog 2"
                     /calculated_mol_wt=73998
     Region          14..217
                     /region_name="B41"
                     /note="Band 4.1 homologues; smart00295"
                     /db_xref="CDD:214604"
     Region          211..307
                     /region_name="FERM_C_ERM"
                     /note="FERM domain C-lobe/F3 of the ERM family; cd13194"
                     /db_xref="CDD:270015"
     Site            order(253..254,256..262,271,292,295..296,299)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:270015"
     Site            order(253,256..263,271,292,295..296,299)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:270015"
     Site            order(289,293)
                     /site_type="other"
                     /note="phosphoinositide binding site [chemical binding]"
                     /db_xref="CDD:270015"
     Site            292..307
                     /site_type="other"
                     /note="actin binding site 2 [polypeptide binding]"
                     /db_xref="CDD:270015"
     Region          341..460
                     /region_name="ERM_helical"
                     /note="Ezrin/radixin/moesin, alpha-helical domain;
                     pfam20492"
                     /db_xref="CDD:466641"
     Region          443..>558
                     /region_name="GET2"
                     /note="GET complex subunit GET2; pfam08690"
                     /db_xref="CDD:400847"
     Region          555..632
                     /region_name="ERM_C"
                     /note="Ezrin/radixin/moesin family C terminal; pfam00769"
                     /db_xref="CDD:459932"
     CDS             1..632
                     /gene="Mer"
                     /coded_by="XM_017138496.3:195..2093"
                     /db_xref="GeneID:108055222"
ORIGIN      
        1 mslfgskknr slsvrvstfd selefklepr asgqdlfdlv crtiglresw yfglqyvdtr
       61 snvswlkmek rvrdqrvelh agnnnvyvfs fyakffpenv seeliqeitq hlfflqvkqs
      121 ilsmdiycrp easvllasya vhvqygpydy etykdgmlag gellpkgvtd qyqmtpemwe
      181 eriktwymdh epmtrdevem eylkiaqdld mygvnyfpit nknktklwlg vtsvglniyd
      241 erdkltpktt fqwneirhvs fddkkftirl vdakvsnfif ysqdlhinkm ildlckgnhd
      301 lymrrrkpdt meiqqmkaqa keekqrrqie rkkfirekkl rekaeherye leksmehlqn
      361 emrmasdalr rseetkelyf eksrvneeqm qlteckanhf ktemdrlrer qmkierekhe
      421 lekkirdadf yvhqltvend kreaeteklr kelicakmae reatarllnf lnsgrksstd
      481 slltaassvs hvantaaist psllttssst ndietaggae ltgnylaqgd nssgisddfe
      541 pkefiltdne meqitnemer nhleylrssk kqvqnqlqvl rseiaphkie enqssfdils
      601 eaqikagenk ystlkklksg stkarvaffe el