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serine/threonine-protein kinase minibrain isoform X2 [Stomoxys


LOCUS       XP_013113455             840 aa            linear   INV 02-SEP-2023
            calcitrans].
ACCESSION   XP_013113455
VERSION     XP_013113455.1
DBLINK      BioProject: PRJNA1009844
DBSOURCE    REFSEQ: accession XM_013258001.2
KEYWORDS    RefSeq.
SOURCE      Stomoxys calcitrans (stable fly)
  ORGANISM  Stomoxys calcitrans
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Stomoxys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081555) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963082655.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..840
                     /organism="Stomoxys calcitrans"
                     /db_xref="taxon:35570"
                     /chromosome="4"
     Protein         1..840
                     /product="serine/threonine-protein kinase minibrain
                     isoform X2"
                     /calculated_mol_wt=91656
     Region          147..486
                     /region_name="PKc_DYRK1"
                     /note="Catalytic domain of the protein kinase,
                     Dual-specificity tYrosine-phosphorylated and -Regulated
                     Kinase 1; cd14226"
                     /db_xref="CDD:271128"
     Site            order(167..171,175,188,190,204,224,240..243,246,248..249,
                     289,291,293..294,296,309,312,321,323..326,328,365)
                     /site_type="active"
                     /db_xref="CDD:271128"
     Site            order(167..171,175,188,190,224,240..243,246,289,291,
                     293..294,296,309)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:271128"
     Site            order(204,248,289,291,312,321,323..326,328,365)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:271128"
     Site            308..328
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:271128"
     CDS             1..840
                     /gene="LOC106091473"
                     /coded_by="XM_013258001.2:1134..3656"
                     /db_xref="GeneID:106091473"
ORIGIN      
        1 myrlddtsga amdkakqkls aayvssaaaa vesgsgggrq rhaplygrfv geeelpathr
       61 evmhhrsspt sssevramqa ripthfrdpa taplrklsvd liktykhine vyyakkkrra
      121 qqtqgeddss nkkerklynd gydddnhdyi ikhgekfldr yeidsligkg sfgqvvkayd
      181 heeqgyvaik iiknkkpfln qaqievklle mmnradaenk yyivklkrhf mwrnhlclvf
      241 ellsynlydl lrntnfrgvs lnltrkfaqq lctallflst pelniihcdl kpenillcnp
      301 krsaikivdf gsscqlgqri yqyiqsrfyr spevllgipy dlaidmwslg cilvemhtge
      361 plfsgcnevd qmnkivevlg mppkylldqa hktrkffdkv vsdgsyvlkk sqngrkykpp
      421 gsrklhdilg vetggpggrr mdepghsvad ylkfkdlilr mldfdpktrv tpyyalqhnf
      481 fkrtsdestn tgagtvqpgs iaisspsvss tssstaalvp gqmlsasavq hseqqshgll
      541 mhpstqqpns lsgaasgqsg nfirsrgisg ngglggpqsf dqsslliksl yeqqqqqqql
      601 laaqqslgll spanssscss ttqnssninn shhqyplamd cdppatqqsm vhsstqqqpp
      661 ppplphhhny apaslpldlv hhplsaaash lmmtdssvit asaagpayss wsssgpsnhv
      721 fgmpppssgh vgslsgvglp tssmvvggdm vqtplqthmq qqqqhhqklq qqqmqhsqrr
      781 tdsqarmmps gssasnssns asvgpggggg ggggsassts gnasspmvgv cvqqspvvih