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serine/threonine-protein kinase PAK mbt [Stomoxys calcitrans].


LOCUS       XP_013108572             675 aa            linear   INV 02-SEP-2023
ACCESSION   XP_013108572
VERSION     XP_013108572.1
DBLINK      BioProject: PRJNA1009844
DBSOURCE    REFSEQ: accession XM_013253118.2
KEYWORDS    RefSeq.
SOURCE      Stomoxys calcitrans (stable fly)
  ORGANISM  Stomoxys calcitrans
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Stomoxys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081555) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963082655.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Stomoxys calcitrans"
                     /db_xref="taxon:35570"
                     /chromosome="4"
     Protein         1..675
                     /product="serine/threonine-protein kinase PAK mbt"
                     /calculated_mol_wt=73120
     Region          9..54
                     /region_name="CRIB_PAK_like"
                     /note="PAK (p21 activated kinase) Binding Domain (PBD),
                     binds Cdc42p- and/or Rho-like small GTPases; also known as
                     the Cdc42/Rac interactive binding (CRIB) motif; has been
                     shown to inhibit transcriptional activation and cell
                     transformation mediated by the...; cd01093"
                     /db_xref="CDD:238526"
     Site            order(11,14,17,19,22,39,43)
                     /site_type="other"
                     /note="GTPase interaction site [polypeptide binding]"
                     /db_xref="CDD:238526"
     Region          397..657
                     /region_name="STKc_PAK_II"
                     /note="Catalytic domain of the Serine/Threonine Kinase,
                     Group II p21-activated kinase; cd06648"
                     /db_xref="CDD:270815"
     Site            order(411..415,419,432,434,463,479..483,485..486,489,524,
                     526..529,531,541..542,545,558..562,564,591,600..602)
                     /site_type="active"
                     /db_xref="CDD:270815"
     Site            order(411..415,419,432,434,463,479..483,485..486,489,
                     528..529,531,541..542)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270815"
     Site            order(414..415,443,524,526..528,545,558..562,564,591,
                     600..602)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270815"
     Site            541..564
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270815"
     CDS             1..675
                     /gene="LOC106087910"
                     /coded_by="XM_013253118.2:130..2157"
                     /db_xref="GeneID:106087910"
ORIGIN      
        1 mfskkkkkpl ismpsnfehr vhtgfdkreq ryvglpmqwa sivgnnqilk stnrplplvd
       61 pseitpteil dlktivrphh nnnkadttsl nssiaaqsti gggggglgtg qhvhvmgmdn
      121 gsamgggivl pktshvarsn slrssspprv rrdlrgnanv ppavpeeres issgggvnai
      181 sttvhgmnsn isgykpqqqi agataphgmy ggqqhangia ggplavrtdf stqsgagslq
      241 frsgaphmhg qqtspvgsia sntrsthshi sshshghhmn tntaimnnlp mypspqgqmh
      301 gqpppalpph gahhqqqqll sqqqpgkqll asdqnqnphq mhlhgktasr assssggtvg
      361 iggtsatggs tatapppkqe prltheqfrs alqmvvsagd prenldnfmk igegstgtvc
      421 iatdkstgrq vavkkmdlrk qqrrellfne vvimrdyhhp nivetyssfl vndelwvvme
      481 yleggaltdi vthsrmdeeq iatvckqclk alaylhsqgv ihrdiksdsi llaadgrvkl
      541 sdfgfcaqvs qelpkrkslv gtpywmspev isrlpygpev diwslgimvi emvdgeppff
      601 nepplqamrr irdmqppnlk nahkvsprlq sfldrmlvrd paqrataael lahpflrqag
      661 ppsllvplmr nsrqh