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LOCUS XM_044396092 6464 bp mRNA linear INV 09-DEC-2024 (Ptp4E), transcript variant X3, mRNA. ACCESSION XM_044396092 VERSION XM_044396092.2 DBLINK BioProject: PRJNA1194641 KEYWORDS RefSeq. SOURCE Drosophila takahashii ORGANISM Drosophila takahashii Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_091683) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 9, 2024 this sequence version replaced XM_044396092.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_030179915.1-RS_2024_12 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 12/07/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..6464 /organism="Drosophila takahashii" /mol_type="mRNA" /strain="IR98-3 E-12201" /db_xref="taxon:29030" /chromosome="X" /sex="female" /tissue_type="Whole fly" /dev_stage="Adult fly" /collected_by="Originally obtained from EHIME-Fly" gene 1..6464 /gene="Ptp4E" /note="Protein tyrosine phosphatase 4E; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 2 Proteins" /db_xref="GeneID:108059141" CDS 365..5578 /gene="Ptp4E" /codon_start=1 /product="tyrosine-protein phosphatase 10D isoform X2" /protein_id="XP_044252027.1" /db_xref="GeneID:108059141" /translation="MDCATRKQQQLRAHHQQQQIQRQTHGRKRRRLQQQQQSHYYHHQ QHVWLVVGILTIFLTQHAQAADLVINVPNASSNDNAFYRIDYSPPFGFPEPNTTIPAS EIGKDIKFSRALPGTEYNFWLYYTNSTHQELLTWTVNITTAPDPPANLSVQLRSSKSA FITWRPPGTGRYSGFRIRVLGLTDLPFERSYSLDGNETLQLSAKELTPGGSYQVQAYS VYQGKESVAYTSRNFTTKPNTPGKFIVWFRNETTLLVLWQPPFPAGIYTHYRVSITPD DAIQSVLYVEREGEPPGPAQAAFKGLVPGREYNISVQTVSEDETSSVPTTARYLTVPE RVLNVTFDETYTTSSSFRVRWEPPRTYSEFDAYQVMLSTSRRIFNVPRAAEGESVHFD YPDVLEPGRSYEVVVKTIADNVNSWPASGEVTLRPRPVRSLGGFLDDRSNALHISWEP AETGKQDAYRISYHEQTNASEVPALFPVASESQITTNLTEYTLDSLLAGRRYLIAVQA LSKGVASNASDITRYTRPAAPLIQELKSIDHGLMLSWRSDVNSRQDRYEVHYQRNGTR EERTMATNETSLTIHYLHPGSGYEVKVHAISHGVRSEPHSYFQAVFPKPPQNLTLQTV HTNLVVLRWQPPEGSDFSEYVVRYRTDASPWQRISGLHENEARIEDMHYGERYLVQVN TVSFGIESPHPLELNVTMPPQPVSNVVPLVDSRNLTLEWPRPDGHVDFYTLKWWPTDE AERVEFKNVSQLEDLSSPSVRIPIEELSPGRQYRFEVQASSNGIRSGTTHLSTRTMPL IQSDVFIANAGHEQGQDETITLSYTPTPADSTRFDIYRFSMGDPKIKDKEKLANDTER KLSFSGLTPGKLYNVTVWTVSGGVASLPVQRLYRLHPLPINDLRALQVAAREITLHWE APAGEYTDFELQYLSADEEAPQLLQNVTKKTEISLQNLRPYHNYTFTVVVRAGSTPST DSDVSGSTLMRSSAPISASYQTLAAPPGKVDYFQPSDVQPGEVTFEWILEAGEQHGPI DNFRITCQNADDAADVASFEFPANATQGRISGLVPGNQYTFRIQAKSALGFGAEREHI QVMPILAPPVPEPSVTPLEVSRTSSTIEISFRQGYFSNAHGMVRSYTIIIAEDVGKNA SGLEMPSWQDVQAYTVWLPYQAIEPYNPFFTSNGSRRNALEAEHFTIGSSSCEKHQTG YCNGPLRAGTTYRIKVRAFTDEDKFTDTAYSSPITTERSDTVIVAATMAAVLLVAMVL LVVYCQHRCQLIRRASKLARMQDELAALPEGYVTPNRPVHVKDFAEHYRLMSADSDFR FSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINA NYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPV DRVAMFYGDIKVQLIIDTHFHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQS LVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAM RKERVFMVQTEQQYVCIHQCLLAVLEGKEHLLADSLELHANDGYEERQPQTKMGTLPI RASLARAEELDADLMADKDLEQQQQQAEAKDENDEEDEDEEDDDQQPLNNETTATLSS ASCSSSSQDVHVDLKDLQAKEHPKQEKESRKICSGTKSHSDTESDSEDEDEEGPVTKD GAVTDEDGWWY" misc_feature <623..>1345 /gene="Ptp4E" /note="Fibronectin type 3 domain [General function prediction only]; Region: FN3; COG3401" /db_xref="CDD:442628" misc_feature order(1073..1075,1274..1276,1319..1321) /gene="Ptp4E" /note="Interdomain contacts [active]" /db_xref="CDD:238020" misc_feature 1082..1327 /gene="Ptp4E" /note="Fibronectin type III domain; Region: fn3; pfam00041" /db_xref="CDD:394996" misc_feature 1256..>2584 /gene="Ptp4E" /note="Fibronectin type 3 domain [General function prediction only]; Region: FN3; COG3401" /db_xref="CDD:442628" misc_feature order(1322..1327,1331..1336) /gene="Ptp4E" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature 2468..2722 /gene="Ptp4E" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:238020" misc_feature order(2468..2470,2669..2671,2714..2716) /gene="Ptp4E" /note="Interdomain contacts [active]" /db_xref="CDD:238020" misc_feature 3041..3292 /gene="Ptp4E" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:238020" misc_feature order(3359..3361,3557..3559,3602..3604) /gene="Ptp4E" /note="Interdomain contacts [active]" /db_xref="CDD:238020" misc_feature 3377..3616 /gene="Ptp4E" /note="Fibronectin type III domain; Region: fn3; pfam00041" /db_xref="CDD:394996" misc_feature order(3605..3610,3614..3619) /gene="Ptp4E" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature 3719..4081 /gene="Ptp4E" /note="TM proximal of protein tyrosine phosphatase, receptor type J; Region: PTP_tm; pfam18861" /db_xref="CDD:465889" misc_feature 4412..5077 /gene="Ptp4E" /note="catalytic domain of R3 subfamily receptor-type tyrosine-protein phosphatases and similar proteins; Region: R3-PTPc; cd14548" /db_xref="CDD:350396" ORIGIN 1 acacattcgt tgtttttttt ttgcagtgcg cttcggtctt gttttcgtgt ccgttttcgg 61 cgctccgttc gtatgtttgt ctccttttgg cagcctgttt tgtttaacaa atgccagtaa 121 caagttttcg agagtgcaat acaagtgcaa tattaattaa gtaataataa aaacctacat 181 aaatgtatac cgagtgcata tgtatgcgtg tgcaatacaa acgaatgacc atgttatagc 241 catacaaaat ataaaacaaa aaccataaaa cacctccctc ctcccccctc cccaacaaaa 301 aaataaaaga aaacaaaaat ctgcgaaacc ttcgacaatc attgagtttt actgtacttg 361 aaaaatggac tgtgccacgc gaaaacaaca acaattacgg gcacatcatc agcagcaaca 421 aatacaaagg caaacacatg gacgaaagcg gcggcgatta caacaacaac agcaaagcca 481 ctactaccac caccaacaac acgtgtggct tgttgttggg attttgacaa tttttttgac 541 tcagcatgca caagcagccg atctggtgat taatgttcca aatgcgagca gcaacgacaa 601 cgccttctac aggatagact acagtccgcc cttcggcttc ccggagccga acaccacgat 661 cccggccagc gagattggca aggacatcaa gttctcgaga gctctgccgg gcacggagta 721 caacttttgg ttgtactaca ccaattccac gcatcaggag ctgctcacct ggacggtgaa 781 cataacgaca gctcccgatc cgccggcgaa cctgagcgtt cagctgcgct ccagcaagag 841 tgccttcata acgtggcgac cgccgggaac tggtcgctat tcgggattcc ggatccgggt 901 gctgggcctc acggatctgc ccttcgagcg aagctactcg ctggatggca acgaaacgct 961 gcagctgtcg gccaaggaac tcactcccgg gggcagctat caggttcagg cctactccgt 1021 ctatcagggc aaggaatcgg tggcctatac gagtcgcaat ttcaccacaa aacccaacac 1081 tccgggcaag ttcatcgttt ggttccggaa cgagaccacg ctgctggtgt tgtggcaacc 1141 cccctttccg gccggaatct acacgcacta cagggtctcc ataacgccgg acgatgccat 1201 ccagagtgtt ttgtacgtgg aacgcgaggg tgagccacct ggaccggcgc aggcagcctt 1261 caagggtctc gttcccggca gggagtacaa tatatcggtg caaacggttt ccgaggatga 1321 gacgtcatcg gttccgacca cagcccgata tctgaccgta ccggaacgtg tcctcaatgt 1381 caccttcgac gagacctaca caacatcgag ttcctttcgc gtgagatggg aaccaccgcg 1441 aacgtatagc gaattcgatg cctaccaggt gatgctctcg acgtcgagaa ggatattcaa 1501 cgttccccgc gctgcggaag gcgaatcggt tcactttgac tatcccgatg tcttggaacc 1561 tggtcgcagc tacgaggtgg tggtcaaaac aatagcggat aacgtgaact cctggccagc 1621 cagcggagag gttacgttgc gtccacgacc cgttcgcagt ctgggtggat tcctcgacga 1681 tcgcagcaat gctctgcaca tttcctggga gccggcggaa acggggaaac aggatgccta 1741 ccgaataagc taccacgagc agacgaacgc aagtgaagtg ccggctctct ttccggttgc 1801 cagtgaatcg caaattacca cgaatctcac ggaatacaca ctggattccc tgctggcggg 1861 acgccgttac ctaattgccg tgcaagccct gtccaaagga gtggcctcca atgccagcga 1921 catcacgcga tacacacgtc cggcggcgcc acttatccag gaactcaaga gcatcgatca 1981 cggactaatg ctcagctggc gcagtgatgt gaactctcgc caggatcgct acgaggtgca 2041 ctaccagcga aatggaacgc gcgaggagcg cacaatggcc accaatgaga cgagcctgac 2101 gatccactac ctgcatcccg gttccggtta cgaggtgaag gtgcacgcca ttagccacgg 2161 cgtccggagc gaaccgcact cctactttca ggcagttttt cccaaaccgc cgcagaatct 2221 cacgctgcag acggtgcaca cgaacctggt ggtgctccgt tggcagccgc cggagggcag 2281 cgacttcagc gagtacgtgg tgcgctatcg cacggacgcc tctccctggc agcggatctc 2341 cgggctgcac gagaacgagg cccggatcga ggacatgcac tacggcgaac gctacctggt 2401 gcaggtgaac accgtgagct tcggcatcga gagtccccat cccctggagc tgaatgtgac 2461 catgccgccg cagccggttt cgaatgtggt gccgttggtg gactcgcgca atctcaccct 2521 cgaatggccg agacccgatg gtcatgtgga cttctacaca ctcaagtggt ggcccaccga 2581 cgaagcggag cgagtggaat tcaagaatgt cagtcagctg gaggatctga gctcccccag 2641 cgttcggatt cccattgaag agctgtcgcc gggtcgtcag tatcgctttg aggtgcaggc 2701 cagctcgaat ggcatccgtt ccgggaccac tcatctctcc actcgcacca tgccactcat 2761 tcaatccgat gtgtttatcg ccaatgcggg acacgaacag ggtcaggatg aaacaataac 2821 cctaagctac acacccacgc cggcggacag cactcggttc gatatctacc gcttctcgat 2881 gggcgatccc aagatcaagg acaaggagaa gctggccaac gatacggaac gcaagctgag 2941 cttctcgggc ctgacgcccg gcaagctgta caacgttacc gtttggacgg tgagcggagg 3001 agtggccagt ttgccggtcc aacggctgta tcgtctgcat ccactgccca tcaatgattt 3061 gcgggctctc caggtggctg ctcgtgagat aaccttgcat tgggaggctc cagctgggga 3121 atacaccgat tttgaactgc agtaccttag tgccgacgag gaggcaccgc aactgctcca 3181 gaatgtgacc aagaagacgg agatttcgct gcagaacctg cgtccgtatc acaattacac 3241 attcaccgtg gtggtgcgag ctggttccac tccaagtacc gattccgatg tctccggcag 3301 caccctaatg cgcagcagtg ctcccatctc ggccagctat caaacgttgg ctgctccacc 3361 tggaaaagtg gactacttcc agccgagcga cgtgcagccc ggcgaggtga ccttcgagtg 3421 gattctggag gcgggcgaac agcacggacc cattgataac tttcgcatca cctgtcagaa 3481 tgccgacgat gcagcggatg tggcaagctt cgaattcccg gcgaatgcga cgcagggcag 3541 gattagtggc ctagtgcccg gcaatcagta cacattccgc atacaagcca agtctgcctt 3601 gggctttggt gccgaaaggg agcacataca agtaatgccc atactagcgc cgcctgttcc 3661 ggaacccagt gtcacgccgc tggaggtcag cagaacgagc agcaccatcg agattagctt 3721 caggcagggc tacttctcca atgcccacgg catggtcaga tcctacacga taatcatagc 3781 cgaggatgtg ggcaagaatg cgtcgggcct ggagatgccc agctggcagg atgtgcaggc 3841 atataccgtg tggttgccct accaggccat cgagccatat aatcccttct tcaccagcaa 3901 tggcagtcgg cggaacgcgc tggaggcgga gcactttacg ataggatcgt ccagttgcga 3961 gaaacatcag acgggctatt gcaatggtcc gctaagggct gggaccacct acaggatcaa 4021 ggtgcgtgcc tttacggacg aggataagtt cacggacacg gcctacagtt caccgataac 4081 caccgaacgc agtgataccg tgattgtggc cgccaccatg gcggctgtgt tgctggtggc 4141 catggtgctg ctggtggtct actgccagca ccgctgccaa ctgatccgcc gcgcctccaa 4201 gttggcccgc atgcaggacg agctggccgc cctgcccgag ggctatgtca cgcccaatcg 4261 gccggtgcat gtgaaggatt tcgccgagca ctacagactc atgtcggccg attcggactt 4321 ccgtttcagc gaggagttcg aggagctgaa gcatgtgggc cgcgatcagg cctgcagctt 4381 cgccaatctg ccctgcaatc ggccgaagaa tcgattcacc aacatcctgc cctacgatca 4441 ctcgcgcttc aagctgcagc ccgtggacga tgacgatggt tcggattata ttaacgccaa 4501 ctatatgccg ggacacaatt cgccgcgcga gttcatcgtc acccagggcc cgttgcattc 4561 gacgcgcgag gagttctggc ggatgtgctg ggagagcaac tcgcgggcca tcgttatgct 4621 gacgcggtgc ttcgagaagg gtcgcgagaa gtgcgatcag tactggcccg tggatcgggt 4681 ggccatgttc tacggggaca ttaaggtgca gttgattatc gacacgcatt tccacgactg 4741 gagcatatcg gagtttatgg tctcaaggaa ctgcgagtcg cgaataatgc ggcacttcca 4801 cttcaccaca tggccggact ttggagttcc cgagccgccg caatcgctgg tgcgcttcgt 4861 gcgcgccttc cgcgatgtca tcggcacgga tatgcggccc attatcgtcc attgcagcgc 4921 cggagtgggc agatcgggca cattcatagc cctggatcgc atcctgcagc acattcacaa 4981 gtcggactat gtggacatct ttggcatcgt gtttgccatg cgaaaagagc gcgtcttcat 5041 ggtgcagacg gaacagcagt acgtgtgcat ccatcagtgt ttgctggcag tgctcgaggg 5101 caaggagcat ctgctggccg attcgctgga gctgcatgcc aatgatggct acgaagagcg 5161 ccagccgcaa acgaaaatgg gaaccttgcc cattcgagct tctttggcca gggccgagga 5221 actggatgcg gatttaatgg ccgacaagga tctggagcag cagcagcagc aggcggaggc 5281 caaggatgag aatgatgaag aggatgagga cgaggaggat gatgaccagc agccgttgaa 5341 caatgaaacg actgccacct tgtcatcggc cagctgcagc agcagcagtc aggatgtgca 5401 tgtggatctc aaggatctcc aggccaaaga acaccccaag caagagaagg agagcaggaa 5461 aatctgcagc ggcacaaaat cccattcaga caccgaaagt gactcagagg atgaggatga 5521 ggaggggccg gtgaccaagg atggggctgt caccgatgag gatggctggt ggtattgata 5581 gaaaagtcga cttttttcta gatgacgagg gcattgctga gacgggaatc tgaggatgct 5641 tgctgcggga atatctacac atgatatata gtacctatag ttattttttt tacatatact 5701 gtacgtaaaa tctgcctgtg atgtgctgga tgtgatttgt ctacgaaatg gcactcggag 5761 ttgctgtcaa atgagttgag tttgtggccc tcatcccgcc gcaactgcca gccaaatcat 5821 ctgtcgactg gtggagatga tggtgggatg aaggccccgc gttttggcct gtgccattta 5881 tgcgtgtacg tcgtaccgcc tgtttgccat agagctaagc tagctagccc gcttatttaa 5941 tgtaatgccg ccaaattaga ccaaaccaac aagagcgtaa acttaagctt caggtgtaat 6001 aatctattac ctaattttgt atctattcct gtacctatta tctattacct tttgttctgt 6061 cgtgttgtgt atagatttgt acatttgttt ccatttagtg tgcgcgtcga tcgatattat 6121 gactatgctt actattacta ttattaatat tactattact cttaacgatt gtgtattatt 6181 tttattatta ttatatagtt tagttatgtt ttatcgatag actttagtcc attattagtc 6241 agcgaaatgt tggctctaac tgcatgcaaa ccttccattt gctttggggc catccatgtc 6301 ttgaaacaaa tacgagattc cattgtatcc ggccaaagca gcaatagcaa ttgtaacatt 6361 gtgcagttaa agttataagc atttatttta ttgtatttaa ttattttatt tttttaaatg 6421 tgcatctaca caagatcaat aaatttatat tgaaaacatg aaca