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LOCUS XM_044396087 12890 bp mRNA linear INV 09-DEC-2024 (trol), transcript variant X35, mRNA. ACCESSION XM_044396087 VERSION XM_044396087.1 DBLINK BioProject: PRJNA1194641 KEYWORDS RefSeq. SOURCE Drosophila takahashii ORGANISM Drosophila takahashii Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_091683) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_030179915.1-RS_2024_12 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 12/07/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..12890 /organism="Drosophila takahashii" /mol_type="mRNA" /strain="IR98-3 E-12201" /db_xref="taxon:29030" /chromosome="X" /sex="female" /tissue_type="Whole fly" /dev_stage="Adult fly" /collected_by="Originally obtained from EHIME-Fly" gene 1..12890 /gene="trol" /note="terribly reduced optic lobes; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 7 Proteins" /db_xref="GeneID:108055788" CDS 209..12217 /gene="trol" /codon_start=1 /product="basement membrane-specific heparan sulfate proteoglycan core protein isoform X34" /protein_id="XP_044252022.1" /db_xref="GeneID:108055788" /translation="MGSPGSQAPAIAIGISNGRRGHTGSLLLRLLLVAFVLNACHVPP TNAKQITKSKVDDQDFILADTQSLQGSVDLDDDEAFLIPPDSEEKLDKKFTPEGNWWS QGLHRVRRSLNSFFGSDDDDQEKERERQRQRQNNRDAANRQKELRRQQKESQNREKQL RLERQERQRLAKRNNHVVFNRVTDPRKRASDLYDENEASGLNEEETTTYRTYFVVNEP YSDDYKERDSLQFQNLQKLLDEDLRNFFNRNFENNDDEEQEIHSTLERVDQTKDHFKI RVQLRVDLPSSINDFGSKLEQQLNVYKRIDRLGASTDGVFTFTESSVYKYEHQYDIVT PRVIVSGQPITEKPVEAPQEFDEDPIEVALPTDEVEGSGQDSGSCRGDATFQCRRSGK TICDEMRCDGSRDCPDAEDEEGCEVCNELQFKCDNKCLPLNKRCDNRYDCEDQTDEAG CQRYEVEESQPQPQPQPQPEPEPEPEPEPEPEPEPEPEPEEPITDNEQPEQNSECRAT EFRCNNGDCIDIRKRCDHISDCSEGEDENEECPEEEEDSVGIPIGRPPQRPAPKHDWL DELDANEYHVYHPSNVYELANSKNPCASNQFRCATTNVCIPLHLRCDNFYHCNDMSDE KDCEQYQRRTTTTTRRPSTSARPSFTFTFTTQGPGLLERRNSTTSRTTAGSTTRATEA PQWPWATRPTETTTTNPITTVGVATTTRLKPSDCGPDQFFCDDLCYNRSIRCNGHMDC SDGSDEIACSSLSVLPCPQHQCPSGRCYSESERCDRHRHCEDGSDEANCCYADQFRCN NGDCIAESAHCDGNIDCSDQSDELDCGGDSQCLPNQFRCKNGQCVSSTARCNKRSDCL DGSDEQNCANEPNNSGRGTNQLKLKTYPDNQIIKESREVIFRCRDEGPNRAKVKWSRP GGRPLPPGFTDRNGRLEIPNIRVEDAGAYVCEAVGYANYIPGQHVTVNLNVERLNERE IRPDSACTEYQATCMNGECIDKSGICDGHPDCSDGSDEHSCSLGLKCQPNQFMCSNSK CVDRTWRCDGENDCGDNSDETSCDPEPSDAPCRYDEFQCRSGHCIPKSFQCDYMNDCT DGTDEIGCSVPSPMTLPAPSIVVMEYEVLELTCVGTGVPTPTIVWRLNWGHVPEKCES KSYGGTGTLRCPNMRPQDSGAYSCEFINTRGTFYPKTNSIVTVTPVRSDVCKAGFFNM LARKSEECVQCFCFGVSTNCDSANLFTYAIQPPILSHRVVSVELSPFRQIVINEASPG QDLLTLHHGVQFRASNVHYNGRETPFLALPAEYMGNQLKSYGGNLRYEVRYNGNGRPV SGPDVIITGNSFTLTHRVRTHPGQNNRVTIPFLPGGWTKPDGRKGTREDIMMILANVD NILIRLGYLDSTAREVDLINIALDSAGSADQGLGSASLVEKCTCPPGYVGDSCESCAS GYVRQARGPWLGHCVPFTPEPCPAGTYGNPRLGVPCQECPCPHAGANNFASGCQQSPD GDVICRCNEGYAGKRCEHCAQGYQGNPLAPGGVCRKIPDSSCNVDGTYNIYSNGTCQC KDSVIGEQCDTCAPKSFHLNSFTYTGCIECFCSGVGLDCDSSSWYRNQVTSTFGRTRV NHGFALISDYMRNTPVTVPVSMSTQANALSFVGSAEQAGNTLYWSLPAAFLGNKLTSY GGKLSYTLSYSPLPSGIMSRNSAPDVVIKSGEDLRLIHYRKSQVSPSVANTYAVEIKE SAWQRGDELVPNREHVLMALSNITAIYIKATYTTSTKEASLRSVTLDTATATNLGTAR AVEVEQCRCPEGYLGLSCEQCAPGYTRDPEAGIYLGLCRPCECNGHSKYCNSETGECE SCSDNTEGFNCDRCAAGYVGDATRGTSYDCQYDDGGYPTSRPPAPGNQTAECLVNCQQ EGTAGCRGYQCECKRNVAGDRCDQCRPGTYGLSAQNPDGCKECYCSGLTNQCRSASLY RQLIPVDFISTPPLITDEFGDIMDRDNLVPDVPRNVYTYKHTSYTPKYWSLRGSVLGN QLLSYGGRLEYSLIVESVGRDHRGKDVVLIGNGLKLIWSRPDGHDNEQEYHVRLHEDE QWTVEDRGSARQATRADFMTVLSDLQHILILATPKVPTVSTSISNVILESSITTRAPG ATHASDIELCQCPSGYTGTSCESCAPLHYRDASGRCSQCPCDASNTESCGLVSGGNVE CQCRPRWRGDRCREIETNEPTPEPDTSTDDPVRTQIIVSIARPEITILPVGGSLTLSC TGRMRWTNSPVFVNWYKQGSHLPEGVEVQGGNLQLFNLQISDSGIYICQAVSNETGHS FTDHVSITVSQEDQRSPAHIVDLPNDVTFEEYVSNEIVCEVEGNPPPTVTWTRVDGHA DAQSTRTDNNRLVFDSPRKSDEGRYRCQAENSLSREEKYVVVYVRSNPPQPPPQQDRL YITPQEVNGVAGDSFQLSCQFTSAASLRYDWSHDGRSLSASSPRNVVVRGNVLEVRDA NVRDSGTYTCVAFDLRTRRNFTESARVYIEQPNEPGILGDKPHILTLEQNIIIVQGED LSITCEASGTPYPSIKWTKVQENLAENVRISGNVLTIYGGRSENRGLYSCIAENSHGS DQSSTSIDIEPRERPSLTIDTATQKVSVGSQASLYCAAQGIPEPTVEWVRTDGQPLSP RHKVQAPGYVVIDDIVLDDSGTYECRASNIAGQVSGLATINVQEPTLVRIEPDRQHHI VTQGDELSLSCVGSGVPTPSVFWSFEGRDVDRMGVPEGAVFAQPFRTNTADVKIFRVS KENEGIYVCHGSNDAGEDQQYIRVEVQPRRGDVGAGGDDNGDVDTRQPPNRPQIQPNP LSNERLTTELGNNVTLICNVDNVNTEWERVDGTPLPHNAYTVRNTLVIVFVEPQNLGQ YRCNGIGRDGRVEAHVVRELVLLPLPRITFYPNIPLTVELGQNLDVYCQVENVRPEDV HWTTDNNRPLPSSVRIEGNVLRFASITQAAAGEYRCSATNQYGSRSKNARVVVKQPSG FQPVPHSQVQQRQVGDSIQLRCRLTTQYGDEVRGNIQFNWYREDGSPLPRGVRPDSQV LQLVKLQPEDEGRYICNSYDLGSGQQLPPVSIDLQVLTVPAAPQNPIYLPPVAPPRSP ERILEPQLSLSVQSSNLPAGDGTTVECFSSDDSYPDVVWERADGAPLSENVQQVGNNL VISNVASTDAGNYVCKCKTDEGDLYTTSYKLEVEEQPHELKSSKIVYAKVGGNADLQC GADEDRQPSYRWSRQYGQLQAGRSLQNEKLSLDRVQANDAGTYVCSAQYSDGETVDFP NILVVTGAIPQFRQEPRSYMSFPTLSNSSFKFNFELTFRPENADGLLLFNGQTRGSGD YIALSLKDRYAEFRFDFGGKPLLVRAEEPLALDEWHTVRVSRFKRDGYIQVDDQHPVA FPTSQHQQIPQLELIEDLYIGGVPNWEFLPAEAVGQQSGFVGCISRLTLQGRTVELIR EAKFKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCVCQPGWTGRDCAIEGTQCTAGV CGSGRCENTENDMECLCPLNRAGDRCQYNEILNEQSLNFKSNSFAAYGTPKVTKVNIT LSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLP LNRWTRIEIRRRLGEGILKVGDGPERKAKAPGSDRILSLKTHLFVGGVDRSTVKINRD VNITKGFDGCISKLYNSQKSVNLLGDIRDAANVQNCGEANEIDDDEYEMPVALPSPKV AENERQLMAPCASDPCENGGSCSEQEDMAICSCPFGFSGKHCQNHLQLSFNASFRGDG YVELNRSHFQPALEQTYSHIGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGY VEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAMLELDQILDTGDTRPTINKA MKLPGNVFVGGAPDVAAFTGFRYKDNFNGCIVVVEGETVGQINLSSAAINGVNANVCP ANDEPLGGTEPPVV" misc_feature 458..>715 /gene="trol" /note="Coiled-coil domain-containing protein 66; Region: CCDC66; pfam15236" /db_xref="CDD:434558" misc_feature 1361..1453 /gene="trol" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; Region: LDLa; cd00112" /db_xref="CDD:238060" misc_feature order(1361..1363,1388..1390,1421..1426) /gene="trol" /note="putative binding surface [active]" /db_xref="CDD:238060" misc_feature order(1400..1402,1409..1411,1421..1423,1439..1444) /gene="trol" /note="calcium-binding site [ion binding]; other site" /db_xref="CDD:238060" misc_feature 1430..1444 /gene="trol" /note="D-X-S-D-E motif; other site" /db_xref="CDD:238060" misc_feature 1460..1561 /gene="trol" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; Region: LDLa; cd00112" /db_xref="CDD:238060" misc_feature order(1475..1477,1496..1498,1529..1534) /gene="trol" /note="putative binding surface [active]" /db_xref="CDD:238060" misc_feature order(1508..1510,1517..1519,1529..1531,1547..1552) /gene="trol" /note="calcium-binding site [ion binding]; other site" /db_xref="CDD:238060" misc_feature 1538..1552 /gene="trol" /note="D-X-S-D-E motif; other site" /db_xref="CDD:238060" misc_feature 1718..1807 /gene="trol" /note="Low-density lipoprotein receptor domain class A; Region: LDLa; smart00192" /db_xref="CDD:197566" misc_feature order(1736..1738,1760..1762,1793..1798) /gene="trol" /note="putative binding surface [active]" /db_xref="CDD:238060" misc_feature 1982..2089 /gene="trol" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; Region: LDLa; cd00112" /db_xref="CDD:238060" misc_feature order(1997..1999,2024..2026,2057..2062) /gene="trol" /note="putative binding surface [active]" /db_xref="CDD:238060" misc_feature order(2036..2038,2045..2047,2057..2059,2075..2080) /gene="trol" /note="calcium-binding site [ion binding]; other site" /db_xref="CDD:238060" misc_feature 2066..2080 /gene="trol" /note="D-X-S-D-E motif; other site" /db_xref="CDD:238060" misc_feature 2354..2455 /gene="trol" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; Region: LDLa; cd00112" /db_xref="CDD:238060" misc_feature order(2369..2371,2390..2392,2423..2428) /gene="trol" /note="putative binding surface [active]" /db_xref="CDD:238060" misc_feature order(2402..2404,2411..2413,2423..2425,2441..2446) /gene="trol" /note="calcium-binding site [ion binding]; other site" /db_xref="CDD:238060" misc_feature 2432..2446 /gene="trol" /note="D-X-S-D-E motif; other site" /db_xref="CDD:238060" misc_feature 2483..2575 /gene="trol" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; Region: LDLa; cd00112" /db_xref="CDD:238060" misc_feature order(2486..2488,2510..2512,2543..2548) /gene="trol" /note="putative binding surface [active]" /db_xref="CDD:238060" misc_feature order(2522..2524,2531..2533,2543..2545,2561..2566) /gene="trol" /note="calcium-binding site [ion binding]; other site" /db_xref="CDD:238060" misc_feature 2552..2566 /gene="trol" /note="D-X-S-D-E motif; other site" /db_xref="CDD:238060" misc_feature 2576..2680 /gene="trol" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; Region: LDLa; cd00112" /db_xref="CDD:238060" misc_feature order(2591..2593,2615..2617,2648..2653) /gene="trol" /note="putative binding surface [active]" /db_xref="CDD:238060" misc_feature order(2627..2629,2636..2638,2648..2650,2666..2671) /gene="trol" /note="calcium-binding site [ion binding]; other site" /db_xref="CDD:238060" misc_feature 2657..2671 /gene="trol" /note="D-X-S-D-E motif; other site" /db_xref="CDD:238060" misc_feature 2696..2800 /gene="trol" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; Region: LDLa; cd00112" /db_xref="CDD:238060" misc_feature order(2711..2713,2735..2737,2768..2773) /gene="trol" /note="putative binding surface [active]" /db_xref="CDD:238060" misc_feature order(2747..2749,2756..2758,2768..2770,2786..2791) /gene="trol" /note="calcium-binding site [ion binding]; other site" /db_xref="CDD:238060" misc_feature 2777..2791 /gene="trol" /note="D-X-S-D-E motif; other site" /db_xref="CDD:238060" misc_feature 2843..3049 /gene="trol" /note="Immunoglobulin domain; Region: Ig_3; pfam13927" /db_xref="CDD:464046" misc_feature 3143..3247 /gene="trol" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; Region: LDLa; cd00112" /db_xref="CDD:238060" misc_feature order(3158..3160,3182..3184,3215..3220) /gene="trol" /note="putative binding surface [active]" /db_xref="CDD:238060" misc_feature order(3194..3196,3203..3205,3215..3217,3233..3238) /gene="trol" /note="calcium-binding site [ion binding]; other site" /db_xref="CDD:238060" misc_feature 3224..3238 /gene="trol" /note="D-X-S-D-E motif; other site" /db_xref="CDD:238060" misc_feature 3263..3367 /gene="trol" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; Region: LDLa; cd00112" /db_xref="CDD:238060" misc_feature order(3278..3280,3302..3304,3335..3340) /gene="trol" /note="putative binding surface [active]" /db_xref="CDD:238060" misc_feature order(3314..3316,3323..3325,3335..3337,3353..3358) /gene="trol" /note="calcium-binding site [ion binding]; other site" /db_xref="CDD:238060" misc_feature 3344..3358 /gene="trol" /note="D-X-S-D-E motif; other site" /db_xref="CDD:238060" misc_feature 3392..3496 /gene="trol" /note="Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; Region: LDLa; cd00112" /db_xref="CDD:238060" misc_feature order(3407..3409,3431..3433,3464..3469) /gene="trol" /note="putative binding surface [active]" /db_xref="CDD:238060" misc_feature order(3443..3445,3452..3454,3464..3466,3482..3487) /gene="trol" /note="calcium-binding site [ion binding]; other site" /db_xref="CDD:238060" misc_feature 3473..3487 /gene="trol" /note="D-X-S-D-E motif; other site" /db_xref="CDD:238060" misc_feature 3548..3775 /gene="trol" /note="Immunoglobulin domain; Region: Ig; cl11960" /db_xref="CDD:472250" misc_feature 3557..3571 /gene="trol" /note="Ig strand B [structural motif]; Region: Ig strand B" /db_xref="CDD:143220" misc_feature 3596..3610 /gene="trol" /note="Ig strand C [structural motif]; Region: Ig strand C" /db_xref="CDD:143220" misc_feature 3665..3679 /gene="trol" /note="Ig strand E [structural motif]; Region: Ig strand E" /db_xref="CDD:143220" misc_feature 3707..3724 /gene="trol" /note="Ig strand F [structural motif]; Region: Ig strand F" /db_xref="CDD:143220" misc_feature 3749..3760 /gene="trol" /note="Ig strand G [structural motif]; Region: Ig strand G" /db_xref="CDD:143220" misc_feature 4070..4462 /gene="trol" /note="Laminin B (Domain IV); Region: Laminin_B; pfam00052" /db_xref="CDD:459652" misc_feature 4631..4792 /gene="trol" /note="Laminin EGF domain; Region: Laminin_EGF; pfam00053" /db_xref="CDD:395007" misc_feature order(4631..4633,4637..4639,4673..4675,4703..4705, 4709..4711,4736..4738) /gene="trol" /note="EGF-like motif [active]" /db_xref="CDD:238012" misc_feature 4811..4924 /gene="trol" /note="Laminin-type epidermal growth factor-like domai; Region: EGF_Lam; smart00180" /db_xref="CDD:214543" misc_feature 5165..5575 /gene="trol" /note="Laminin B (Domain IV); Region: Laminin_B; pfam00052" /db_xref="CDD:459652" misc_feature <5576..5656 /gene="trol" /note="Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; Region: EGF_Lam; cd00055" /db_xref="CDD:238012" misc_feature 5678..5827 /gene="trol" /note="Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; Region: EGF_Lam; cd00055" /db_xref="CDD:238012" misc_feature order(5681..5683,5687..5689,5708..5710,5729..5731, 5738..5740,5765..5767) /gene="trol" /note="EGF-like motif [active]" /db_xref="CDD:238012" misc_feature <5936..6028 /gene="trol" /note="Laminin EGF domain; Region: Laminin_EGF; pfam00053" /db_xref="CDD:395007" misc_feature 6224..6628 /gene="trol" /note="Laminin B (Domain IV); Region: Laminin_B; pfam00052" /db_xref="CDD:459652" misc_feature 6905..7153 /gene="trol" /note="Immunoglobulin like; Region: IG_like; smart00410" /db_xref="CDD:214653" misc_feature 6938..6952 /gene="trol" /note="Ig strand B [structural motif]; Region: Ig strand B" /db_xref="CDD:409353" misc_feature 6986..7000 /gene="trol" /note="Ig strand C [structural motif]; Region: Ig strand C" /db_xref="CDD:409353" misc_feature 7043..7057 /gene="trol" /note="Ig strand E [structural motif]; Region: Ig strand E" /db_xref="CDD:409353" misc_feature 7085..7102 /gene="trol" /note="Ig strand F [structural motif]; Region: Ig strand F" /db_xref="CDD:409353" misc_feature 7130..7141 /gene="trol" /note="Ig strand G [structural motif]; Region: Ig strand G" /db_xref="CDD:409353" misc_feature <7232..7393 /gene="trol" /note="Immunoglobulin domain; Region: Ig_3; pfam13927" /db_xref="CDD:464046" misc_feature 7484..7735 /gene="trol" /note="Immunoglobulin like; Region: IG_like; smart00410" /db_xref="CDD:214653" misc_feature 7517..7531 /gene="trol" /note="Ig strand B [structural motif]; Region: Ig strand B" /db_xref="CDD:409544" misc_feature 7556..7570 /gene="trol" /note="Ig strand C [structural motif]; Region: Ig strand C" /db_xref="CDD:409544" misc_feature 7625..7639 /gene="trol" /note="Ig strand E [structural motif]; Region: Ig strand E" /db_xref="CDD:409544" misc_feature 7667..7684 /gene="trol" /note="Ig strand F [structural motif]; Region: Ig strand F" /db_xref="CDD:409544" misc_feature 7772..8014 /gene="trol" /note="Immunoglobulin domain; Region: Ig; cl11960" /db_xref="CDD:472250" misc_feature 7823..7837 /gene="trol" /note="Ig strand B [structural motif]; Region: Ig strand B" /db_xref="CDD:409570" misc_feature 7862..7876 /gene="trol" /note="Ig strand C [structural motif]; Region: Ig strand C" /db_xref="CDD:409570" misc_feature 7919..7933 /gene="trol" /note="Ig strand E [structural motif]; Region: Ig strand E" /db_xref="CDD:409570" misc_feature 7961..7978 /gene="trol" /note="Ig strand F [structural motif]; Region: Ig strand F" /db_xref="CDD:409570" misc_feature 8000..8011 /gene="trol" /note="Ig strand G [structural motif]; Region: Ig strand G" /db_xref="CDD:409570" misc_feature 8066..8296 /gene="trol" /note="Immunoglobulin I-set domain; Region: I-set; pfam07679" /db_xref="CDD:400151" misc_feature 8090..8104 /gene="trol" /note="Ig strand B [structural motif]; Region: Ig strand B" /db_xref="CDD:409544" misc_feature 8129..8143 /gene="trol" /note="Ig strand C [structural motif]; Region: Ig strand C" /db_xref="CDD:409544" misc_feature 8192..8206 /gene="trol" /note="Ig strand E [structural motif]; Region: Ig strand E" /db_xref="CDD:409544" misc_feature 8234..8251 /gene="trol" /note="Ig strand F [structural motif]; Region: Ig strand F" /db_xref="CDD:409544" misc_feature 8273..8284 /gene="trol" /note="Ig strand G [structural motif]; Region: Ig strand G" /db_xref="CDD:409544" misc_feature 8333..8596 /gene="trol" /note="Immunoglobulin like; Region: IG_like; smart00410" /db_xref="CDD:214653" misc_feature 8363..8377 /gene="trol" /note="Ig strand B [structural motif]; Region: Ig strand B" /db_xref="CDD:409548" misc_feature 8402..8416 /gene="trol" /note="Ig strand C [structural motif]; Region: Ig strand C" /db_xref="CDD:409548" misc_feature 8534..8551 /gene="trol" /note="Ig strand F [structural motif]; Region: Ig strand F" /db_xref="CDD:409548" misc_feature 8969..9199 /gene="trol" /note="Immunoglobulin like; Region: IG_like; smart00410" /db_xref="CDD:214653" misc_feature 8996..9010 /gene="trol" /note="Ig strand B [structural motif]; Region: Ig strand B" /db_xref="CDD:409541" misc_feature 9035..9049 /gene="trol" /note="Ig strand C [structural motif]; Region: Ig strand C" /db_xref="CDD:409541" misc_feature 9095..9109 /gene="trol" /note="Ig strand E [structural motif]; Region: Ig strand E" /db_xref="CDD:409541" misc_feature 9137..9154 /gene="trol" /note="Ig strand F [structural motif]; Region: Ig strand F" /db_xref="CDD:409541" misc_feature 9233..>9436 /gene="trol" /note="Immunoglobulin like; Region: IG_like; smart00410" /db_xref="CDD:214653" misc_feature 9266..9280 /gene="trol" /note="Ig strand B [structural motif]; Region: Ig strand B" /db_xref="CDD:409390" misc_feature 9314..9337 /gene="trol" /note="Ig strand C [structural motif]; Region: Ig strand C" /db_xref="CDD:409390" misc_feature 9383..9397 /gene="trol" /note="Ig strand E [structural motif]; Region: Ig strand E" /db_xref="CDD:409390" misc_feature 9578..9784 /gene="trol" /note="Immunoglobulin domain; Region: Ig_3; pfam13927" /db_xref="CDD:464046" misc_feature 9872..10072 /gene="trol" /note="Immunoglobulin like; Region: IG_like; smart00410" /db_xref="CDD:214653" misc_feature 9896..9910 /gene="trol" /note="Ig strand B [structural motif]; Region: Ig strand B" /db_xref="CDD:409390" misc_feature 9935..9949 /gene="trol" /note="Ig strand C [structural motif]; Region: Ig strand C" /db_xref="CDD:409390" misc_feature 9992..10006 /gene="trol" /note="Ig strand E [structural motif]; Region: Ig strand E" /db_xref="CDD:409390" misc_feature 10034..10051 /gene="trol" /note="Ig strand F [structural motif]; Region: Ig strand F" /db_xref="CDD:409390" misc_feature 10136..10579 /gene="trol" /note="Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; Region: LamG; cd00110" /db_xref="CDD:238058" misc_feature 10646..10744 /gene="trol" /note="EGF-like domain; Region: EGF; pfam00008" /db_xref="CDD:394967" misc_feature 10886..11347 /gene="trol" /note="Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; Region: LamG; cd00110" /db_xref="CDD:238058" misc_feature 11507..11605 /gene="trol" /note="Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; Region: EGF_CA; cd00054" /db_xref="CDD:238011" misc_feature 11630..12091 /gene="trol" /note="Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; Region: LamG; cd00110" /db_xref="CDD:238058" polyA_site 12890 /gene="trol" /experiment="COORDINATES: polyA evidence [ECO:0006239]" ORIGIN 1 attaggttgc gcgccatcgt tccaggcggt cgcacattcc acgtgccata gccgtaacaa 61 caacctgcca accgcttaaa accaaactca aatacgaacc gaaactgcct tcacacacac 121 aagtacctaa accaaatcta aatagctgcc aaaagaaacc aaaaattcca gagacgtcgt 181 agcatccgtt ccccggaaga agaagaagat gggatcgccg ggatcccaag cgcccgcgat 241 cgcgatcggg atcagtaacg ggcggagagg tcacacgggg tcgctgctcc tgcgcctcct 301 tctcgtggcc ttcgtcctca acgcctgcca cgtacccccg accaatgcca agcaaattac 361 gaaaagtaaa gttgatgacc aggactttat actggccgac acacaatcgc tgcagggcag 421 cgttgacctt gacgatgacg aagcgttcct gattcctccg gattccgaag agaagttgga 481 taagaagttc acgccggagg gcaactggtg gagccagggg ctccatcgtg ttcgccgctc 541 cctaaatagc ttcttcggct ccgacgacga tgatcaggaa aaggaacgtg agcgtcagag 601 gcaaaggcaa aataatcgcg atgccgccaa ccggcaaaag gaacttcggc gccagcaaaa 661 ggagagccag aaccgcgaga agcagctgcg attggagcgc caggagaggc agcgccttgc 721 caagcggaac aatcacgtgg tcttcaatcg cgtcaccgat ccccgcaagc gggcatccga 781 cctttacgac gagaacgagg catctggcct aaacgaggag gaaaccacca cctatcgcac 841 ctactttgtt gttaatgagc catattcaga cgactacaag gagcgggaca gcctccagtt 901 ccagaatctg caaaaacttc ttgacgagga cctgcgcaac ttcttcaatc gcaatttcga 961 aaataacgat gatgaagagc aggaaatcca tagcacccta gagcgagtcg atcaaaccaa 1021 ggaccatttt aaaattcgcg tgcaacttag ggtagatctg cccagttcaa tcaacgactt 1081 tggaagtaag ttggagcaac aactgaatgt ctacaagcga atcgatcgtt tgggtgccag 1141 taccgatggc gtcttcacct ttaccgaatc gagcgtctac aaatacgaac accaatacga 1201 tattgtgaca ccgagagtaa ttgtatctgg acaaccgata actgaaaaac cagtcgaagc 1261 accccaagaa ttcgatgagg atcctatcga agttgcattg cccacggatg aggtggaggg 1321 ctccggccaa gattccggta gctgtcgcgg cgatgccacc ttccagtgtc gaaggagtgg 1381 aaagactatt tgcgatgaaa tgcgatgcga tggatctcgc gattgtcccg atgccgagga 1441 cgaggaaggc tgcgaggttt gcaacgaact tcagttcaag tgcgataaca agtgtctgcc 1501 gctcaataag cgctgcgata atcgatacga ttgtgaggat cagacggacg aggctggttg 1561 tcaacggtac gaagtagaag agtctcagcc tcagccgcag ccgcaacctc agcctgaacc 1621 ggaacctgaa cctgaacctg agcctgagcc tgaacctgaa ccagaaccag aacctgaaga 1681 gcctataaca gacaatgaac agcctgagca aaactcagaa tgccgggcca ccgagttcag 1741 atgcaacaat ggggactgca tcgatattag aaagcgttgc gatcacattt cggactgtag 1801 cgaaggcgag gacgagaacg aggagtgccc cgaggaggag gaagatagtg tgggcatacc 1861 cattggccgt ccaccgcaga ggccagcgcc caaacacgac tggctggacg aattggacgc 1921 caatgagtac cacgtctatc atccaagtaa tgtctatgag ttggccaatt ccaagaatcc 1981 ctgtgccagc aatcaatttc gctgcgccac cacgaatgtg tgcatccccc tgcatttgcg 2041 ttgcgataat ttctatcact gcaacgatat gagcgatgag aaggactgcg agcagtatca 2101 acgacgcacc accaccacca cccgacgacc ttcgacctcg gcccggccct ccttcacctt 2161 caccttcacg acccaggggc caggcttgct ggagcgtcgc aatagcacca ccagtagaac 2221 caccgcaggc agcaccacca gagccaccga agcaccacaa tggccatggg caaccagacc 2281 caccgagacc acgaccacta acccaataac aacagttggc gtagcgacca ccacacgact 2341 aaagcccagc gactgcggtc cggatcagtt cttctgcgat gatttatgct ataatcgctc 2401 tattcgatgc aatggccata tggattgctc agatggcagt gatgagatcg cttgtagctc 2461 gctgtcagtg cttccatgtc cacagcacca gtgtcccagt ggcaggtgtt attcggaaag 2521 tgagcgatgc gatcgccaca ggcactgcga ggatggctcc gatgaggcca actgctgtta 2581 cgcggatcaa ttccgctgca ataatggtga ctgcattgcg gaatcggctc attgcgatgg 2641 aaatatcgat tgtagcgacc agtccgatga actcgactgc ggaggagact cgcagtgtct 2701 gcccaaccaa ttccgctgca agaatggcca atgtgtgagc tctacagcgc gttgcaacaa 2761 gcgttccgat tgtttggatg gctccgatga gcagaattgt gccaatgaac ctaacaactc 2821 cggacgtgga acgaaccaat tgaaactcaa gacctatccc gacaaccaaa tcattaagga 2881 gagtcgtgag gtcatcttcc gttgccgtga cgaaggtccc aaccgcgcca aggtcaagtg 2941 gtcgcgaccc ggcggacgtc ccctgccccc cggtttcacc gatcgcaatg gccgcctgga 3001 gatccccaac atcagggtgg aggatgctgg cgcctatgtc tgcgaggccg tgggctatgc 3061 caactatatt cccggtcagc acgtcaccgt aaacctcaac gtcgagcgct taaacgaacg 3121 cgaaatccgt ccggactcag cctgtacgga gtaccaggcc acctgcatga acggcgagtg 3181 tatcgataag tcgggcatct gcgatggaca tccggactgt tcggatggct ccgatgagca 3241 cagctgcagt ttgggtttga agtgtcagcc caaccagttc atgtgctcca attccaagtg 3301 tgtggatcgc acctggcgct gtgatggcga gaacgactgc ggcgataact ccgatgagac 3361 ctcttgcgat ccggaaccaa gtgatgctcc gtgccgatac gacgaattcc agtgccgcag 3421 cggtcattgc attcccaaga gcttccagtg cgactatatg aacgattgta ccgatggtac 3481 cgatgaaatt ggatgctcgg tgccctctcc aatgacccta cccgcaccct cgattgtcgt 3541 gatggagtac gaggtcctcg agctgacctg cgtgggcacc ggcgtcccga cgccgacgat 3601 cgtgtggcgt ctcaactggg gccatgtgcc cgagaagtgt gaatcgaaga gctacggcgg 3661 aaccggaacc ctgcgctgtc cgaacatgag gccccaggac agtggtgcct actcgtgcga 3721 gttcatcaac acacgcggca ccttctatcc gaaaacgaac tcgattgtca ccgttacgcc 3781 ggtgcgctcg gatgtctgca aggccggatt cttcaatatg ctggcccgca agtcggagga 3841 atgcgtccag tgcttctgct ttggcgtttc gaccaactgt gacagtgcca atttgttcac 3901 ctacgccatt cagccaccga tcctttcgca ccgcgtggtc agcgttgaac tcagtccgtt 3961 ccgtcaaatt gtcatcaatg aggctagtcc gggtcaggat ctgctcacct tgcaccatgg 4021 tgttcagttc agggcatcga acgtacacta caacggccgg gagacaccat tcttggccct 4081 gcccgctgag tatatgggca accagctgaa gtcctatggc ggcaatctgc gctacgaggt 4141 caggtacaat ggcaacggta gaccggtcag cggacccgat gtcatcatca ccggcaacag 4201 tttcacgcta acccatcgcg ttcgcactca tccgggtcag aacaacaggg tgactattcc 4261 cttcctgccg ggaggctgga cgaagccgga tggtcgcaag ggaacgcgag aggacatcat 4321 gatgatactg gccaatgtgg acaatattct gattcgactg ggctacctgg atagcacagc 4381 tcgcgaagtg gatctgataa atatcgcctt ggattcggcc ggaagtgccg atcagggatt 4441 gggcagtgcc tcgctcgtgg agaagtgcac ctgtccgccc ggctatgttg gtgattcgtg 4501 cgagtcctgt gcctcgggct atgttcgcca ggcccgcgga ccttggctgg gtcattgtgt 4561 gcccttcacc ccggaaccgt gcccagcggg aacctacggc aatccccgac ttggtgttcc 4621 ctgccaggag tgtccgtgcc cccacgcggg cgccaataac tttgccagcg gctgccaaca 4681 gagtcccgat ggcgatgtga tttgccgctg caacgaaggc tatgccggca agaggtgcga 4741 gcactgcgcc cagggttacc agggtaatcc gttggcaccg ggaggagtct gtcgcaagat 4801 acccgatagt tcgtgcaatg tcgacggcac ctacaacatc tacagcaatg gaacgtgcca 4861 gtgcaaggat agcgtgattg gcgaacagtg cgacacctgc gcgccgaaga gtttccacct 4921 caattcgttc acctacaccg gttgcatcga gtgcttctgc agtggagtgg gcttggattg 4981 tgacagtagt tcgtggtatc gcaaccaggt caccagcacc tttggacgaa cgcgcgtcaa 5041 tcatggattc gccctgatta gcgactatat gcgcaatacc ccggtaacgg tgcccgtttc 5101 catgtccacc caggccaatg ccttgagctt cgtgggatcc gccgagcagg ccggtaatac 5161 gctctactgg agtcttcccg ccgccttcct gggcaacaag ctgacctcgt acggaggcaa 5221 gttgagctac acgctcagct acagtcccct gcccagcggc attatgtcgc gcaacagtgc 5281 ccccgatgtg gtgatcaaga gcggcgagga tctgaggctc atccattaca ggaagtcgca 5341 ggtcagtccc agtgtggcca acacctatgc cgtggagatc aaggagagcg catggcagcg 5401 cggcgatgaa ctggtgccta accgtgaaca cgtcctgatg gccctcagca atattacggc 5461 catctatatc aaggccacgt acacgactag caccaaggag gcctcgctgc gatcggtcac 5521 attggatacg gccacggcca ccaatctggg caccgcacgt gccgtcgaag tggagcagtg 5581 ccgctgtccc gagggctatt tgggtctctc ctgcgagcag tgtgctcctg gctatacgcg 5641 cgatccggag gcaggaatct atctgggtct ctgcaggccc tgcgagtgca atggacattc 5701 caagtattgc aacagtgaga caggcgaatg cgaaagctgt tccgacaaca ccgaaggatt 5761 caattgtgac cgatgcgccg ccggctatgt gggtgatgcc acccgaggaa cttcgtacga 5821 ctgtcaatac gatgacggcg gctatccgac gtcgcgtcca ccggcaccgg gcaatcagac 5881 ggccgaatgc ctggtgaatt gccaacagga gggaaccgcc ggttgccgcg gctaccagtg 5941 cgagtgcaag aggaatgtgg ctggcgatcg atgcgatcag tgccgccccg gaacctatgg 6001 actgtcggcc caaaatccgg acggttgcaa ggagtgctac tgctccggac tgaccaacca 6061 gtgccgctcg gcgtctctct accgccagct gatacccgtg gacttcattt cgacgccacc 6121 attgataaca gacgaattcg gcgacatcat ggatagggat aaccttgtgc ccgacgtgcc 6181 caggaatgtg tatacctaca agcacacctc ctacacgccc aagtactgga gcctgagggg 6241 tagtgtgctg ggcaaccagc tgttgtcgta cggcggccgc ttggagtaca gcctgattgt 6301 ggagtccgtt ggccgggacc atcgtggcaa ggatgtggtc ctaattggca acggactcaa 6361 gctgatctgg tcgcgacccg atggccatga caacgagcag gaataccatg tgcgtttgca 6421 tgaggacgag cagtggacgg ttgaggatcg tggatcggca cgacaggcca cgcgggccga 6481 cttcatgact gtgctgtcgg atctgcagca catcctgatc ctggccacac ccaaggtgcc 6541 cacggtcagc acctcgatta gcaatgtcat cctggagagt tcgataacca cgagagcgcc 6601 tggagctacg catgcctccg atatcgagtt gtgccagtgt ccatccggtt atacgggcac 6661 ttcctgtgag tcctgcgcac cactgcacta ccgcgacgcc tctggacgct gcagtcagtg 6721 tccttgcgac gcttccaaca cggaatcctg cggcttggtc agcggcggta acgtcgaatg 6781 ccagtgcagg ccacgctgga ggggtgatcg ctgccgggaa attgaaacta acgaaccgac 6841 tccggaaccg gataccagta ccgatgatcc cgtgcgcacc cagatcatag tgtcgattgc 6901 caggccagag attaccattc tgcccgtggg tggatcgctg accctcagct gtaccggtcg 6961 aatgcgctgg accaatagcc cagtgtttgt gaactggtac aagcagggca gtcacctgcc 7021 cgagggagtc gaggtgcaag gcggtaatct gcagctgttc aacctgcaga tcagcgattc 7081 tggaatctac atctgccagg ccgtaagcaa cgagaccggc cacagcttta cggaccacgt 7141 ctccatcacc gtttcccagg aggaccaacg ctcgccggct cacattgtgg atttgcccaa 7201 cgacgtgacc ttcgaggagt acgtaagcaa tgagatcgtc tgcgaggtgg agggcaaccc 7261 accacccact gtcacctgga ctcgcgtgga tggccatgcg gacgcccaaa gtacgcgaac 7321 ggacaacaat cggctggtct tcgattcgcc gaggaaatcg gacgagggtc gctatcgctg 7381 ccaggcagag aatagcctga gtcgggagga gaagtacgta gtcgtgtatg tccggagcaa 7441 tcctccccag ccgccgccgc agcaggatcg tttgtacatc acaccgcagg aggtgaacgg 7501 tgtggccggt gactccttcc agttgtcctg ccaattcacc agcgctgcct ctctgcgcta 7561 cgattggtcc cacgatggtc gctccctgtc cgcgtcgtca ccccgaaatg ttgtggtccg 7621 cggaaatgtc ctggaagtcc gcgatgccaa cgttcgcgac tccggcacct acacctgtgt 7681 ggccttcgac ctgcgcaccc gacgcaactt caccgagagc gcacgggtct acatcgagca 7741 gcccaacgag ccgggaatcc ttggcgacaa gccgcatatc ttgaccttgg agcagaacat 7801 cataattgtg caaggcgagg acttgagcat cacatgtgag gcaagtggaa cgccctatcc 7861 ctcgattaag tggaccaagg tgcaggagaa tctggccgaa aatgtccgca tcagtggcaa 7921 tgtgctcacc atctacggag gccgcagtga gaatcgtggt ctttactcct gcatcgccga 7981 gaactctcac ggcagcgatc agtccagcac aagcatcgat attgaacccc gggagcggcc 8041 gagtcttacg attgatacgg ccacccaaaa ggtttcggtt ggctcccagg cgtcccttta 8101 ctgtgccgcc cagggcattc ccgaaccgac cgtcgagtgg gttcgaacgg atggtcagcc 8161 actgtcgccg cgtcacaagg tccaggcacc cggctatgtt gtgatcgatg acattgtgct 8221 cgatgatagc ggtacctacg agtgccgggc gagcaacata gctggccagg tgagcggctt 8281 ggccaccatt aacgtccagg agccaactct tgtgcggatc gaaccagata ggcaacacca 8341 tatcgtcacc cagggcgacg aactctcgct cagctgcgtg ggcagtggcg tccctactcc 8401 ttcggtcttt tggagtttcg agggaagaga cgttgacagg atgggagtac cggaaggtgc 8461 tgtttttgcg caacctttcc gaaccaacac tgccgacgtg aaaatcttcc gggtgagcaa 8521 ggagaacgaa ggcatctacg tctgtcacgg atccaatgac gcgggtgaag atcaacaata 8581 cattcgcgtg gaggtacaac ccagacgggg tgacgtcggt gcaggaggag atgacaatgg 8641 tgatgtcgat acccgacagc cccccaatcg gccccaaatc caaccgaatc cattgagcaa 8701 cgaacgcctg accaccgaat tgggcaacaa tgtgaccctc atctgcaacg tggacaacgt 8761 gaacacggaa tgggaacgcg tcgatggcac acccctgccg cacaatgcct acacggtgag 8821 aaatacgctg gtgattgtct tcgtggagcc gcagaatctg ggtcagtacc gctgcaatgg 8881 aatcggtcgc gatggacgtg tggaggccca tgtggtgagg gagctggttc tcctgcccct 8941 gcccaggatc accttctatc ccaacatccc gctgaccgtg gagctgggcc agaacttgga 9001 tgtctactgc caggtggaga acgtgcgtcc ggaggacgtg cattggacca ccgacaacaa 9061 tcgaccactg cccagttccg tacgcatcga gggcaatgtc ctcaggttcg cgtccatcac 9121 tcaggctgct gccggtgaat accgctgctc ggccaccaat caatatggaa gccgatcgaa 9181 gaacgccagg gtggtggtga aacagcccag tggcttccag cccgttcccc actcgcaggt 9241 gcaacagcgt caggtgggcg actccatcca gttgcgatgc cgcctgacca cccagtacgg 9301 cgacgaggtt cgcggcaata tccagttcaa ctggtaccgt gaggacggca gccccttgcc 9361 ccgcggtgtc cgtccggata gccaggtgct gcagctggtt aaattgcagc ccgaggacga 9421 gggccgctac atctgcaact cgtacgattt gggcagcggg cagcaactgc cccccgtctc 9481 catcgacttg caagtactaa cggtaccagc ggctccccag aaccccatct acctgccgcc 9541 agtggcgcca ccacgttcgc ccgaaaggat cctcgagccc caactgagcc tgagtgtaca 9601 atcctcgaac ctgccagccg gcgacggcac caccgtcgag tgcttctcct ccgatgactc 9661 ctacccagat gtcgtgtggg aacgcgccga tggagctcca ctcagcgaaa atgtccagca 9721 agtgggcaat aacctggtga ttagtaacgt ggcctccacc gatgccggta actatgtgtg 9781 caagtgcaag acggacgagg gagatctgta taccaccagc tacaaactgg aggtcgagga 9841 gcagccccat gaactgaaga gctccaagat agtctacgcc aaggttggcg gaaatgccga 9901 cttgcagtgc ggagccgatg aagatcgaca gcccagctac cgttggtctc gccaatacgg 9961 acaacttcag gcgggacgca gtctgcagaa tgagaaactt tcgttggatc gcgttcaggc 10021 caacgatgcc ggaacttatg tttgttcggc ccaatacagc gatggcgaga cggttgactt 10081 ccccaacatt ctggttgtga ccggggcgat tccccagttc cgccaggagc cccgcagcta 10141 catgagcttc cccacgctct cgaactcctc gttcaagttc aacttcgagc tgaccttccg 10201 gccggaaaac gccgacggac tgctgctctt caatggacag acccgcggaa gcggtgacta 10261 tatcgcactc tcgctgaagg atcgctatgc ggagttccgg ttcgattttg gcggtaaacc 10321 gttgctggtg cgagcggagg agccactggc tttggatgaa tggcacacgg tgcgcgtgag 10381 tcgcttcaag cgggatggct acatccaggt ggacgaccag catccggtgg ccttccccac 10441 ctcccagcat cagcagatac cccagttgga actgattgag gatctgtaca ttggcggcgt 10501 gcccaactgg gagttcctgc ccgccgaggc ggtgggtcag caatcaggct tcgtgggctg 10561 cattagccgg ctgaccctgc agggacgcac cgtggagctg atccgggagg ccaagttcaa 10621 ggagggcatc accgattgcc ggccctgcgc ccagggaccc tgccagaaca agggcgtctg 10681 cctggagagc cagacggagc aggcctacac ctgcgtctgc cagccgggct ggactggccg 10741 ggattgtgcc atcgagggca cccagtgcac cgcaggagtt tgcggctcgg gacgctgcga 10801 gaatacggag aacgacatgg agtgcctgtg cccgctgaac agggcaggcg atcgatgcca 10861 gtacaatgag attctaaatg aacagagctt gaatttcaag agcaacagct ttgcggccta 10921 cggaactccc aaggtcacca aagtaaacat cacactctcc gttcgtcccg cgagcctgga 10981 ggactctgtg atcctgtaca cggcggaatc cactctgccc agcggcgatt acctggcttt 11041 ggtccttcgc ggtggccacg cggagctgct gatcaacacg gccgcccgct tggatcccgt 11101 ggtggtgcgt tcggcggaac cgctgcccct caatcgctgg accagaatcg agatcaggcg 11161 tcgcctgggc gagggaatcc tcaaggtggg cgatggaccc gagcgaaagg ccaaggcacc 11221 gggatccgat cgcattctgt cgctcaagac ccacctcttt gtgggcggcg tcgatcggtc 11281 gaccgtaaag atcaaccgtg atgtgaacat caccaagggc ttcgatggct gcatctcgaa 11341 gctgtacaac tcgcagaaat ccgtcaatct gctgggtgac atcagggatg cggcgaatgt 11401 ccagaactgt ggggaggcga atgagataga tgacgatgag tatgagatgc cagtagcgct 11461 gccatcgcct aaggtcgccg agaatgaacg tcagctgatg gcgccgtgtg ccagtgatcc 11521 ctgcgagaac gggggaagct gcagcgagca ggaggacatg gccatctgct cctgtccctt 11581 cggcttcagc ggcaaacact gccagaatca cctccagctg agcttcaatg cctcgttccg 11641 cggcgatggc tacgtggagc tgaaccgcag ccacttccaa cccgccctgg agcagacgta 11701 ctcccacatt ggcattgtgt tcaccaccaa caagccgaat ggcctgcttt tctggtgggg 11761 ccaggaggcc ggggaggagt acaccggaca ggacttcatt gccgccgccg tggtcgatgg 11821 ctatgtggag tactcgatga ggctcgatgg cgaggaggcg gtcattcgga acagcgatat 11881 ccgcgtggac aatggcgagc ggcacattgt gatcgccaag cgggatgaga acaccgccat 11941 gctggaactc gatcagatcc tggacacggg cgatacgcga cccaccatca acaaggcaat 12001 gaagctgccg ggcaatgtgt ttgtcggtgg cgctcctgat gtcgcggcat tcacgggctt 12061 ccgctacaag gacaatttca acggctgcat tgtggtcgtc gagggcgaaa ccgtgggcca 12121 aattaacctt agttcagctg ccatcaatgg agtgaatgcc aacgtgtgtc ccgctaacga 12181 cgaacctctg ggaggaaccg aaccgccagt cgtctgagga cacaaccagc aaccgaaatt 12241 agctttttaa ttaaacatta acaaatgaaa caaaaagaaa aacaattttt atatatacaa 12301 catatgaata agccccaagc aaacctacaa aaaattgaat attatacgac gaacagataa 12361 tataaaaaca aaaaaagaga gaaacgatca cttctactac aattgcttct tcgatcctta 12421 agtctaggtt aaagattgta gcaagaaaac aagcgaatat cacaaacatt tatttaacaa 12481 gaacgccatg cgagaagtga aacgaaacag aaacaataat gcaattaatg cagataatac 12541 agataaagcc tagaacccta agaactaact aactaactcg aacaagaaca acaacgcata 12601 ctagccaact gcaaccacaa caaccacaat agtgaaggca ttttaattat aattttagtc 12661 tctagcttat aactatgact acgactcgtt ttttttgtga gcccagtgta aaatgttgga 12721 aatcggaaat tggccctaca cacaaacaca cacaagttat taattaaata ccaattgata 12781 ccatataatg ataaatgaaa tactatgaat gcaactattg tgaacgaacg aaaaccgttg 12841 agtggataaa aagcataagc agaagatata ttaaaatgaa atcaacaaca