PREDICTED: Drosophila obscura rho GTPase-activating protein 15
LOCUS XM_022364339 2062 bp mRNA linear INV 14-MAY-2021
(LOC111072454), transcript variant X2, mRNA.
ACCESSION XM_022364339
VERSION XM_022364339.2
DBLINK BioProject: PRJNA728747
KEYWORDS RefSeq.
SOURCE Drosophila obscura
ORGANISM Drosophila obscura
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT MODEL REFSEQ: This record is predicted by automated computational
analysis. This record is derived from a genomic sequence
(NW_024542752.1) annotated using gene prediction method: Gnomon.
Also see:
Documentation of NCBI's Annotation Process
On May 14, 2021 this sequence version replaced XM_022364339.1.
##Genome-Annotation-Data-START##
Annotation Provider :: NCBI
Annotation Status :: Full annotation
Annotation Name :: Drosophila obscura Annotation
Release 101
Annotation Version :: 101
Annotation Pipeline :: NCBI eukaryotic genome annotation
pipeline
Annotation Software Version :: 8.6
Annotation Method :: Best-placed RefSeq; Gnomon
Features Annotated :: Gene; mRNA; CDS; ncRNA
##Genome-Annotation-Data-END##
FEATURES Location/Qualifiers
source 1..2062
/organism="Drosophila obscura"
/mol_type="mRNA"
/isolate="BZ-5 IFL"
/db_xref="taxon:7282"
/chromosome="Unknown"
/sex="male"
/tissue_type="whole fly"
/dev_stage="Adult fly"
/geo_loc_name="Serbia: Babin Zub"
/collection_date="2017"
gene 1..2062
/gene="LOC111072454"
/note="Derived by automated computational analysis using
gene prediction method: Gnomon. Supporting evidence
includes similarity to: 5 Proteins, and 100% coverage of
the annotated genomic feature by RNAseq alignments,
including 17 samples with support for all annotated
introns"
/db_xref="GeneID:111072454"
CDS 261..1814
/gene="LOC111072454"
/codon_start=1
/product="rho GTPase-activating protein 15 isoform X2"
/protein_id="XP_022220031.1"
/db_xref="GeneID:111072454"
/translation="MHTTMQTTTTGNNGRPGLVAVAVPVTPGTPDSAHIIIGAAGFVA
HERRQPREKTLMNCFRDRSTSSTGGGPPAYYMRGHSTTSTTLLRLESNAGAGGVGGGS
GNALDQAGVEAGRPEAVRWVRELKSRPNKLALLKSSSTRDLTRLLLEDGNGSGGTSAV
LVSNTSLDVCSSNSSSASSPLAGGRAKARARDRDREQRSLSKECCGSCSKRWHELKQR
MHTLEQDLLAQVSYSQELEAKQVEMTRQLSELMQEKDKDRDRDREKQRGPSGGAGKSN
VRPSRLVAWMNLSNWWKSRPSVETLREQRIFFDEPCFDTELEMVLKHDQQRTVPRIVV
DCCDLIEHKYRRSTQPIEGIYRQCGDYNKIQTLRFSIDANDYEALRQTDVDIHTLTGV
LKLFLREIKSPLVSVNEAKTFIGTPHQWLLTELAVKLDTLKRLIRSLPESNRDTMDYI
FGHFNRLTKVPLQQISAETLSISVTPSIFHTVPQGVHMQDIQQLLREGETLADCVKLM
IEYHSRIFE"
misc_feature 1248..1793
/gene="LOC111072454"
/note="GTPase-activator protein (GAP) for Rho-like
GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases.
Small GTPases (G proteins) cluster into distinct families,
and all act as molecular switches, active in their
GTP-bound form but inactive when bound to...; Region:
RhoGAP; cd00159"
/db_xref="CDD:238090"
misc_feature order(1326..1328,1440..1442,1452..1454,1665..1667,
1674..1679,1764..1766)
/gene="LOC111072454"
/note="GTPase interaction site; other site"
/db_xref="CDD:238090"
misc_feature 1326..1328
/gene="LOC111072454"
/note="catalytic residue [active]"
/db_xref="CDD:238090"
ORIGIN
1 cgtcgtcgtc atctctttcg tttccttgcc gcaccacaca gacgactggc tgtctctgac
61 gtcacttgcc accgcaccca cgccaaaaac aggggcagac aagcaggcag gggagttggg
121 gctggtcagc tgcggcactt gcgataagcc cgaccgaccg accgtgtgca gctgcagctg
181 cagggaaggc gaagcccgat aaaagactcg agatctgtgg cgagagagag agagagagag
241 agagaggaac gaagacgacg atgcacacga cgatgcagac aacgacgacg ggaaacaatg
301 gcaggccagg gctagtggct gtggcagtac cagtgacgcc tggaacacca gactcggcgc
361 acatcataat cggtgccgcc ggctttgtag cccacgagag aagacagccc cgagagaaga
421 ctctgatgaa ctgctttcgc gaccgttcca cgtcttcaac aggcggtgga ccaccagcct
481 actatatgcg cggacacagc accacatcga cgacactgct gcgcctcgag agcaatgcag
541 gtgcaggagg agtaggagga ggctcgggca acgccctaga tcaggcgggc gtcgaggccg
601 gacgaccgga ggccgttcgt tgggtgcgtg agcttaagtc caggcccaac aagctggccc
661 tgctcaagag cagcagcacc agggacttga cgcgcctgct cctggaggat ggcaatggca
721 gcggcggcac atcggcggtg ctggtgtcca acaccagcct ggacgtgtgc tcctccaact
781 ccagttcggc cagcagtccc ctggccggcg gcagggccaa ggcgagggcc agggacaggg
841 atagggagca gcgtagcttg agcaaggagt gctgcggcag ctgctccaag cgctggcacg
901 agctcaagca gcgcatgcac accctggagc aggacctgct ggcccaggtc agctacagcc
961 aggagctgga ggccaagcag gttgagatga cccgccagct cagcgaacta atgcaggaga
1021 aggacaagga cagagacagg gacagagaga agcagcgtgg gccaagcggt ggggcgggta
1081 agagcaatgt gagaccctcg cgtctcgtgg cgtggatgaa cctgtccaac tggtggaaga
1141 gcaggcccag cgtggagacg ctgcgcgagc agcgcatctt cttcgacgag ccctgcttcg
1201 acacggaact ggagatggtg ctgaagcacg accagcagcg cactgtgccg cgcattgtgg
1261 tcgattgctg cgacctcatc gagcacaaat accgccgctc cacgcagccc atcgagggca
1321 tctatcggca gtgcggcgac tacaacaaga tccagacgct gcgctttagc atcgatgcga
1381 atgactatga ggccctgcgg cagacggatg tcgacataca caccctcacg ggtgtgctga
1441 agctctttct gcgcgagatc aagagtccgc tggtcagtgt gaacgaggcc aagacgttca
1501 ttggcacacc ccatcaatgg ttgctcaccg aactggccgt caagctggac acattgaaaa
1561 gactgatacg ctcgctgccg gagagcaatc gcgataccat ggactacatt ttcggccact
1621 tcaatcggct gaccaaggtg ccgctgcagc agatcagcgc cgagacgctg tccatttcgg
1681 tgacaccgtc catattccac acggtgccgc agggcgtgca catgcaggac atacagcagc
1741 tgctgcgcga gggcgaaacg ctggccgatt gcgtcaaact gatgatcgag tatcattcgc
1801 gcatattcga gtaagtgatg gccccctctc cccccaccca gtatcggtga tggtgtatcg
1861 cagtcttcac gccgctccca cccactcgca caacgcatcc ccgcctacgt ccgcccacgc
1921 caccagctgc ttctctgccc cacccgcatc ataccaaccc caaccacttg aattgaatgt
1981 gtctcgctgt gtcgaaagta aaatgctaac cacccgaatc ctcctacaat tcgtatccgt
2041 atccgaatcc aaaattgaac ct