PREDICTED: Drosophila obscura sodium channel protein para
LOCUS XM_022361494 6838 bp mRNA linear INV 14-MAY-2021
(LOC111070739), transcript variant X12, mRNA.
ACCESSION XM_022361494
VERSION XM_022361494.2
DBLINK BioProject: PRJNA728747
KEYWORDS RefSeq.
SOURCE Drosophila obscura
ORGANISM Drosophila obscura
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT MODEL REFSEQ: This record is predicted by automated computational
analysis. This record is derived from a genomic sequence
(NW_024542752.1) annotated using gene prediction method: Gnomon.
Also see:
Documentation of NCBI's Annotation Process
On May 14, 2021 this sequence version replaced XM_022361494.1.
##Genome-Annotation-Data-START##
Annotation Provider :: NCBI
Annotation Status :: Full annotation
Annotation Name :: Drosophila obscura Annotation
Release 101
Annotation Version :: 101
Annotation Pipeline :: NCBI eukaryotic genome annotation
pipeline
Annotation Software Version :: 8.6
Annotation Method :: Best-placed RefSeq; Gnomon
Features Annotated :: Gene; mRNA; CDS; ncRNA
##Genome-Annotation-Data-END##
FEATURES Location/Qualifiers
source 1..6838
/organism="Drosophila obscura"
/mol_type="mRNA"
/isolate="BZ-5 IFL"
/db_xref="taxon:7282"
/chromosome="Unknown"
/sex="male"
/tissue_type="whole fly"
/dev_stage="Adult fly"
/geo_loc_name="Serbia: Babin Zub"
/collection_date="2017"
gene 1..6838
/gene="LOC111070739"
/note="Derived by automated computational analysis using
gene prediction method: Gnomon. Supporting evidence
includes similarity to: 46 Proteins, and 100% coverage of
the annotated genomic feature by RNAseq alignments,
including 7 samples with support for all annotated
introns"
/db_xref="GeneID:111070739"
CDS 237..6689
/gene="LOC111070739"
/codon_start=1
/product="sodium channel protein para isoform X12"
/protein_id="XP_022217186.2"
/db_xref="GeneID:111070739"
/translation="MTEDSDSISEEERSLFRPFTRESLVQIEQRIAAEHEKQKELERK
RAEGEVPQYGRKKKQKEIRYDDEDEDEGPQPDPTLEQGVPIPVRLQGSFPPELASTPL
EDIDPFYSNILTFVVVSKGKDIFRFSASKAMWLLDPFNPIRRVAIYILVHPLFSLFII
TTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILCPFTYLRDAWNWLD
FVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVII
LTMFSLSVFALMGLQIYMGVLTQKCIKKFPLDGSWGNLTDENWAYHNSNNSNWYSEDD
GISFPLCGNISGAGQCEDDYVCLQGFGPNPNYGYTSFDSFGWAFLSAFRLMTQDFWED
LYQLVLRAAGPWHMLFFIVIIFLGSFYLVNLILAIVAMSYDELQKKAEEEEAAEEEAI
REAEEAAAAKAAKLEERANAQAQAAADAAAAEEAALHPEMAKSPTYSCISYELFVGGE
KGNDDNNKEKMSIRSVEVESESVSVIQRQPAPTTAHQATKVRKVSTYTIRNGRGRFGI
PGSDRKPLVLSTYQDAQQHLPYADDSNAVTPMSEENGAIIVPVYYGNLGSRHSSYTSH
QSRISYTSHGDLLGGMAVMGVSTMTKESKLRNRNSRNQSVGATNGGTTCLDPNHKVEH
RDFEIGLECTDEAGKIKHHDNPFIEPVQTQTVVDMKDVMVLNDIIEQAAGRHSRASDR
GVSVYYFPTEDDDEDGPTLKDKALEALMKGIEVFCVWDCCWVWLKLQEWISLIVFDPF
VELFITLCIVVNTMFMAMDHHDMNKEMERILKCGNYFFTATFAIEATMKLCAMSPKYY
FQEGWNIFDFIIVALSLLELGLEGVQGLSVLRSFRLLRVFKLAKSWPTLNLLISIMGR
TMGALGNLTFVLCIIIFIFAVMGMQLFGKNYHDNKDRFPDGDLPRWNFTDFMHSFMIV
FRVLCGEWIESMWDCMHVGDVSCIPFFLATVVIGNLVVLNLFLALLLSNFGSSSLSAP
TADNDTNKIAEAFNRIGRFKSWVKRNIADCFKLIRNKLTNQISDQPSGERTNQISWIW
SEEHGDNELELGHDEILADGLIKKGIKEATQLEVAIGDGMEFTIHGDMKNNKPKKSKY
LNNATMIGNSINHQDNRLEHELNHRGLSLQDDDTASINSYGSHKNRPFKDESHKGSAE
TMEGEEKRDASKEDLGIDEELDEEGELEEGPLDGDIIIHANDEDILDEYPADCCPDSY
YKKFPILAGDDDSPFWQGWGNLRLKTFQLIENKYFETAVITMILMSSLALALEDVHLP
QRPILQDILYYMDRIFTVIFFLEMLIKWLALGFKVYFTNAWCWLDFVIVMVSLINFVA
SLVGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWL
IFAIMGVQLFAGKYFKCEDMNGTKLSHEIIPNRNACESENYTWVNSAMNFDHVGNAYL
CLFQVATFKGWIQIMNDAIDSREVDKQPIRETNIYMYLYFVFFIIFGSFFTLNLFIGV
IIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIV
TDKKFDIVIMLFIGLNMFTMTLDRYDASDTYNAVLDYLNAIFVVIFSSECLLKIFALR
YHYFIEPWNLFDVVVVILSILGLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK
GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKEKSGINDVYNFKTFGQ
SMILLFQMSTSAGWDGVLDAIINEEACDPPDNDKGYPGNCGSATVGITFLLSYLVISF
LIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQQFDPEGTQYIRYDQLSEFL
DVLEPPLQIHKPNKYKIISMDIPICRGDLMYCVDILDALTKDFFARKGNPIEETGEIG
EIAARPDTEGYEPVSSTLWRQREEYCARLIQHAWRKHKTRAEGGGAPSDAEGDGPEDG
DAGGGGGAALMLGVLDVPDAAGDAATTGSHDGATALDPETDPSGVPAAAAVAPQPAGD
GGEGPDGGATADPHESNVNSPTMDGATAGSPGAGSAGSTGRQTAVLVESDGFVTKNGH
KVVIHSRSPSITSRTADV"
misc_feature 690..1544
/gene="LOC111070739"
/note="Ion transport protein; Region: Ion_trans;
pfam00520"
/db_xref="CDD:459842"
misc_feature 1893..2393
/gene="LOC111070739"
/note="Cytoplasmic domain of voltage-gated Na+ ion
channel; Region: Na_trans_cytopl; pfam11933"
/db_xref="CDD:463401"
misc_feature 2622..3257
/gene="LOC111070739"
/note="Ion transport protein; Region: Ion_trans;
pfam00520"
/db_xref="CDD:459842"
misc_feature 3333..4106
/gene="LOC111070739"
/note="Sodium ion transport-associated; Region:
Na_trans_assoc; pfam06512"
/db_xref="CDD:461936"
misc_feature 4116..4931
/gene="LOC111070739"
/note="Ion transport protein; Region: Ion_trans;
pfam00520"
/db_xref="CDD:459842"
misc_feature 4899..5057
/gene="LOC111070739"
/note="Inactivation gate of the voltage-gated sodium
channel alpha subunits; Region: Na_channel_gate; cd13433"
/db_xref="CDD:240441"
misc_feature 4944..4955
/gene="LOC111070739"
/note="putative hydrophobic latch; other site"
/db_xref="CDD:240441"
misc_feature 5079..5831
/gene="LOC111070739"
/note="Ion transport protein; Region: Ion_trans;
pfam00520"
/db_xref="CDD:459842"
misc_feature 5862..6005
/gene="LOC111070739"
/note="Voltage-dependent L-type calcium channel,
IQ-associated; Region: GPHH; pfam16905"
/db_xref="CDD:465306"
ORIGIN
1 acaaaagcaa cagcaacaac aactaccaca attgcaacaa caacaataag cagagcatca
61 acgaaagcaa gcagtcaagc gcaacatcga ttgacatcga ttaacgcatc gtgctaagcg
121 gcgggcgcta atcgaacatg gcgcctcgga tatagttgta gctttaatgt agcaggcgac
181 atccatgtgc ctcatgcctt ggaaatctaa ggctctcatc gttggccgca tagacaatga
241 cagaagattc cgactcgata tctgaggaag aacgaagttt gttccgtccc tttacccgcg
301 aatcattggt gcaaatcgaa caacgcattg ccgctgaaca tgaaaagcag aaggagctgg
361 aaagaaagag agccgaggga gaggtgccgc aatatggtcg caagaaaaaa caaaaagaaa
421 tccgatatga tgacgaggac gaggatgaag gtccacaacc ggatcctaca cttgaacagg
481 gtgtgccaat acctgttcga ctgcagggca gcttccctcc ggaattggcc tccactcccc
541 tcgaggatat cgatcccttc tacagcaata tactgacatt cgtagttgta agcaaaggaa
601 aagatatttt tcgcttttct gcatcaaaag caatgtggct gctcgatcca ttcaatccga
661 tacgtcgtgt ggccatttac attttagtgc atccactatt ttcgttattc atcattacca
721 caattctcgt caactgcatc ctgatgataa tgccgacaac gcccacagtt gagtccactg
781 aggtgatatt caccggaatc tacacatttg aatcagctgt taaagtgatg gcacgaggtt
841 tcattttatg cccgtttacg tatcttagag atgcatggaa ttggctggac ttcgtagtaa
901 tagctttagc ttatgtgacc atgggtatag atttaggtaa tcttgcagcc ttgcgaacgt
961 ttagggtgct gcgagcgctt aaaaccgtag ccattgtgcc aggcttgaag accattgtcg
1021 gtgcggtcat cgaatctgta aagaatctgc gcgatgtgat aattttgaca atgttctccc
1081 tgtcggtgtt cgcgctgatg gggctgcaaa tctacatggg cgtgctaacg cagaagtgca
1141 tcaagaagtt cccgctggac ggctcctggg gcaacctgac cgacgagaac tgggcctatc
1201 acaatagcaa caactctaat tggtattcgg aagacgacgg tatatccttt ccgttgtgcg
1261 gtaatatctc tggagcgggg caatgtgaag acgattacgt gtgtctgcag gggttcgggc
1321 cgaacccgaa ctatggctac accagtttcg attcgttcgg ttgggcgttt ctgtccgcct
1381 tccggctgat gacgcaggac ttctgggagg atctgtatca gctggtgttg cgtgccgcag
1441 gaccctggca catgctgttc tttatagtca tcatcttcct aggttcattc tatcttgtga
1501 atttgatttt ggccattgtt gccatgtcgt atgacgaatt gcaaaagaag gccgaagaag
1561 aagaggctgc cgaagaggag gcgatacgtg aagccgagga agctgccgcc gccaaagcag
1621 ccaagctgga ggagcgcgcc aatgcgcagg cccaggccgc cgccgatgca gctgccgccg
1681 aagaggcggc tcttcatccg gagatggcca agagtccgac gtattcgtgc atcagctatg
1741 agctatttgt gggcggcgag aaaggcaacg atgacaacaa caaggagaag atgtccatac
1801 gcagcgttga ggtggagtcg gagtcggtga gcgttataca aagacaacca gcacctacca
1861 cagcacacca agctaccaaa gttcgtaaag tgagcacgta cacgatccgg aatggacgtg
1921 gacgctttgg tatacccggc agcgatcgca agccgttggt attgtcaaca tatcaggatg
1981 ctcagcagca cttgccctat gccgatgatt cgaacgctgt tacgcccatg tccgaggaga
2041 acggtgccat tatagtgccc gtttattatg gaaatctagg ctccaggcat tcatcgtata
2101 cttcgcatca gtccagaata tcgtatacct cacatggcga tctattgggc ggcatggccg
2161 tcatgggcgt cagcacaatg accaaggaga gcaaattgcg aaatcgcaac tcacgcaatc
2221 aatcagtggg cgccaccaat ggcggcacca cctgcctgga ccccaatcac aaggtcgagc
2281 atcgcgactt cgaaatcggt ctggagtgca cggacgaagc tggcaagatt aaacatcatg
2341 acaatccttt tatcgagccc gtccagacac aaacggtagt cgacatgaaa gatgtgatgg
2401 tactgaatga cattatcgaa caggccgctg gtcggcacag tcgggctagt gatcgcggtg
2461 tctccgttta ctatttccca acagaggacg atgatgagga tgggccgaca ttaaaagaca
2521 aggccctcga agcgctaatg aaaggcatcg aagtgttttg tgtgtgggac tgttgctggg
2581 tttggttgaa attgcaggag tggatatcgc tgatcgtctt cgatcccttt gtcgagctct
2641 tcatcacgct gtgcattgtg gtcaacacga tgttcatggc catggaccat cacgacatga
2701 acaaggagat ggaacgcatc cttaagtgcg gaaattattt cttcacggca acattcgcca
2761 ttgaggcaac catgaaactg tgcgccatga gccccaaata ctatttccag gagggctgga
2821 acatctttga cttcatcatt gtggcactct cattgctgga gctgggcctc gagggcgttc
2881 agggcctctc cgtcttgcgt tcgtttcgtt tgctgcgtgt attcaaattg gccaagtcct
2941 ggccaacact taatttactc atttcgatta tgggacgcac catgggcgct ttgggtaatc
3001 tgacatttgt actttgcatt atcatcttca tctttgcggt gatgggaatg caactgttcg
3061 gaaagaatta tcatgataac aaggatcgct tcccggacgg tgacctgccc cgctggaact
3121 tcaccgactt catgcacagc ttcatgatcg tgtttcgggt gctatgcggc gagtggatcg
3181 agtccatgtg ggactgtatg cacgtgggcg atgtatcgtg cattccattc ttcttggcca
3241 ccgttgtcat cggcaattta gtggttctta accttttctt agccctgctt ttgtcaaatt
3301 ttggttcatc tagcttatca gcgccgacag ccgataacga taccaataaa atagccgagg
3361 ccttcaatcg aattgggcga tttaaaagtt gggttaagcg taatattgct gattgtttca
3421 agttaatacg taacaaattg acaaatcaaa taagtgatca accatcaggt gagaggacca
3481 accagatcag ttggatttgg agcgaagagc acggcgacaa cgagctggag ctgggccacg
3541 acgagatact cgccgacggg ctcatcaaga agggcatcaa ggaggcgaca cagctggagg
3601 tggccatcgg tgatggcatg gagttcacga tacacggcga catgaagaac aacaagccga
3661 agaaatccaa atatctaaat aacgcaacga tgattggcaa ctcaattaac caccaagaca
3721 atagactgga acacgagcta aaccatagag gtttgtcctt acaggacgac gacactgcca
3781 gcattaactc atatggtagc cataagaatc gaccattcaa ggatgagagc cacaagggca
3841 gcgccgagac gatggagggc gaggagaagc gggacgccag caaggaggat ttaggtatcg
3901 atgaggagct cgacgaggag ggcgaattgg aggagggccc gctcgacggc gatatcatca
3961 tacatgccaa cgatgaggat atactcgatg aatatccagc tgattgctgc cccgattcgt
4021 actataagaa atttccgatc ttagccggtg atgatgactc gccgttctgg caaggatggg
4081 gcaatttacg actgaaaact tttcaattaa ttgaaaataa atattttgaa acagctgtta
4141 tcactatgat tttaatgagt agcttagctt tggcattaga agatgtacat ctgccacaaa
4201 gacccatact gcaggatatt ttatactata tggacagaat atttacggtt atattcttct
4261 tggaaatgtt aatcaagtgg ctggcgctcg gcttcaaagt gtacttcacg aacgcgtggt
4321 gctggctcga tttcgtcatt gtcatggtat cgcttatcaa cttcgttgct tcacttgttg
4381 gagctggtgg tattcaagcc ttcaagacta tgcgaacgtt aagagcactg agaccactac
4441 gtgccatgtc ccgtatgcag ggcatgaggg tcgtcgttaa tgcgctggta caagctatac
4501 cgtccatctt caatgtgcta ttggtgtgtc taatattttg gctaattttt gccataatgg
4561 gtgtacagct ttttgctgga aaatatttta agtgcgagga catgaatggc acgaagctca
4621 gccacgagat cataccaaat cgcaatgcct gcgaaagcga gaactacacg tgggtgaatt
4681 cagcaatgaa tttcgatcat gtaggtaacg cgtatctgtg ccttttccaa gtggccacct
4741 tcaaaggctg gatacaaatc atgaacgatg ctatcgattc acgagaggtg gacaagcagc
4801 caattcgtga aacgaacatc tacatgtatt tatatttcgt attcttcatc atatttggat
4861 catttttcac actcaatctg ttcattggtg ttatcattga taattttaat gagcaaaaga
4921 aaaaagcagg tggatcatta gaaatgttca tgacagaaga tcagaaaaag tactataatg
4981 ctatgaaaaa gatgggctct aaaaaaccat taaaagccat tccaagacca aggtggcgtc
5041 cacaagcaat agtctttgaa atagtaaccg ataagaaatt cgatatagtc ataatgttat
5101 tcattggtct gaacatgttc accatgacac tcgatcgtta cgatgcgtcg gacacgtaca
5161 acgcggtcct tgactatctc aatgcgatat tcgtagttat tttcagttcc gaatgtctat
5221 taaaaatatt cgctttacga tatcactatt ttattgagcc atggaattta tttgatgtag
5281 tagttgtcat tttatccatc ttaggtctcg tacttagcga tattatcgag aaatacttcg
5341 tatcgccgac actgctccga gtggtgcgcg tggccaaagt gggtcgcgta ctgcgtctgg
5401 tgaagggcgc caagggtata cgaacgctgc tgttcgccct ggccatgtcg ctgccggcgc
5461 tgttcaacat ctgcctgctg ctgttcctgg tcatgttcat cttcgcgata ttcggcatgt
5521 cgttcttcat gcatgtgaag gagaagagcg gcatcaacga cgtctacaac ttcaagacgt
5581 tcggacagag catgatcctg ctctttcaga tgtctacctc agccggttgg gatggtgtac
5641 tcgacgccat tatcaatgag gaagcatgcg atccacccga caacgacaaa ggctatccgg
5701 gcaattgtgg ttcagcgacc gttggaataa cgtttctcct ctcataccta gttataagct
5761 ttttgatagt tattaatatg tacattgctg tcattctcga gaactatagt caggccaccg
5821 aggatgtgca ggagggtctc accgacgacg attacgatat gtactatgag atctggcaac
5881 agttcgatcc ggagggcacc cagtacatac gatacgacca gctgtccgag ttcctcgacg
5941 tgctggagcc cccgctccag attcacaagc ccaacaagta caaaatcata tcgatggaca
6001 tacccatctg tcgcggtgac ctcatgtact gtgtggacat actggacgca ctgaccaaag
6061 actttttcgc gcgcaaaggc aatcccattg aggagacggg cgagattggt gagattgccg
6121 ccaggccgga caccgagggc tacgagcccg tctcctccac cctctggcga cagcgggagg
6181 agtactgtgc ccgcctcatt caacatgcct ggcgcaagca taaaacgcgc gccgagggcg
6241 gtggtgcacc gtccgacgcg gaaggcgacg gccccgaaga tggtgatgcg ggtggcggtg
6301 gcggggcggc gctgatgctg ggtgttctgg atgttccaga tgctgctggc gatgcagcaa
6361 ccactggctc ccatgacggg gcaacggcac tcgatcccga gaccgatcca tcgggagtac
6421 cggcggcagc ggcggtggcc ccacagccag ccggtgacgg cggcgaggga ccggatggag
6481 gagcaacagc cgatccgcac gagagcaatg taaatagtcc gacgatggac ggcgcgacgg
6541 cgggcagccc gggcgcaggg agcgctggca gcactggccg acagacggcc gttctcgtgg
6601 agagcgatgg gtttgtgacc aagaacgggc acaaggttgt aatacactcg cgttcgccga
6661 gcataacgtc gcgcacggcg gatgtctgag ccaggcctcg cccccccctc caagatgcac
6721 gcgagtatta ggtgcaggtg cagatgcagt gcagtggtgg tgccacaaca acaacaacaa
6781 caacagcagg tgccactggt agctgcaatt gcaactgcaa cagcagcaac aggaagaa