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Candida albicans SC5314 Hch1p (HCH1), partial mRNA.


LOCUS       XM_019475459             459 bp    mRNA    linear   PLN 18-APR-2022
ACCESSION   XM_019475459
VERSION     XM_019475459.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (bases 1 to 459)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (bases 1 to 459)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (bases 1 to 459)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 459)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (bases 1 to 459)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. This record is derived from an annotated genomic
            sequence (NC_032094).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Candida albicans SC5314"
                     /mol_type="mRNA"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     gene            <1..>459
                     /gene="HCH1"
                     /locus_tag="CAALFM_C601860CA"
                     /db_xref="GeneID:3641626"
     CDS             1..459
                     /gene="HCH1"
                     /locus_tag="CAALFM_C601860CA"
                     /note="Ortholog of S. cerevisiae Hch1, a regulator of heat
                     shock protein Hsp90; regulated by Gcn4; induced in
                     response to amino acid starvation (3-aminotriazole
                     treatment); mutants are viable"
                     /codon_start=1
                     /transl_table=12
                     /product="Hch1p"
                     /protein_id="XP_019331004.1"
                     /db_xref="CGD:CAL0000176856"
                     /db_xref="GeneID:3641626"
                     /translation="MVVHNPNNWHWIDKNCLPWSKDYLKENIIDTTYEDDSFRFVVTA
                     VDSVSGDCDVTQRKGKVLCIYDMRLQFSLSGAIKKGNEKEEEETISATIVIPEFVHDQ
                     DKDEYVFEIESASQKSEIRKYFVPILKEKLMKFQPDLLEAHAKDVQHATD"
     misc_feature    37..429
                     /gene="HCH1"
                     /locus_tag="CAALFM_C601860CA"
                     /note="Activator of Hsp90 ATPase, N-terminal; Region:
                     Aha1_N; pfam09229"
                     /db_xref="CDD:462716"
ORIGIN      
        1 atggtagttc acaaccctaa caattggcat tggattgaca aaaactgttt gccctggtcc
       61 aaagactatt tgaaggagaa tataatagac actacatacg aagatgacct gttcagattt
      121 gtagtcactg ctgttgattc tgtcagtggt gattgtgatg tgactcaaag aaaggggaag
      181 gtgttatgca tatacgatat gagattacaa tttctgttat ctggagctat caaaaagggc
      241 aatgagaagg aggaagaaga aacaatatca gcaacaattg ttataccaga atttgttcat
      301 gatcaagata aagacgaata cgtttttgag atagaatctg cttctcaaaa atcagaaatt
      361 agaaagtact ttgtaccaat cttaaaggag aaattgatga aatttcaacc tgatttactt
      421 gaagcacatg caaaagatgt tcaacacgca actgattaa