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LOCUS XM_017153811 3836 bp mRNA linear INV 09-DEC-2024 protein (Grip), transcript variant X1, mRNA. ACCESSION XM_017153811 VERSION XM_017153811.3 DBLINK BioProject: PRJNA1194641 KEYWORDS RefSeq. SOURCE Drosophila takahashii ORGANISM Drosophila takahashii Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_091683) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 9, 2024 this sequence version replaced XM_017153811.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_030179915.1-RS_2024_12 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 12/07/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3836 /organism="Drosophila takahashii" /mol_type="mRNA" /strain="IR98-3 E-12201" /db_xref="taxon:29030" /chromosome="X" /sex="female" /tissue_type="Whole fly" /dev_stage="Adult fly" /collected_by="Originally obtained from EHIME-Fly" gene 1..3836 /gene="Grip" /note="Glutamate receptor interacting protein; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 1 Protein" /db_xref="GeneID:108065695" CDS 274..3483 /gene="Grip" /codon_start=1 /product="glutamate receptor-interacting protein 1 isoform X1" /protein_id="XP_017009300.2" /db_xref="GeneID:108065695" /translation="MKLWKSKKPIVGCVPGKSAALKQDQQQQQQQQQQQESHNSSFNG HHHPPTDTALAPMLSVDRAMSPAQSEDSGLAPERGTTYATITLPRNALHLAITFAERN DLSYPPVVGSLSPVGHAADFLAPGDRLHQIDGISTIGLSNQKVMNMLCAGGSDAGPAI VEIEYSLPEYTVSQNSLCVTSKLAQITVERESGCLGLTLRGGADYPLIVTHVRPHGPV YKTGRIKPGDRLLRVDNVSLIGKTLAEAQQIIKCGGHVSGYTNLTIEYDVSVVQSVEF SMGPLIIEIERPMNDKLGLVLCNYTPAMAASGSGSSTPSSGEKIEESTGVFIASILPA SIADRCGALSVGDQVLSIDDTMIEHTAFSPDEVMTILDTSTGRGYTQMQIMPAHALAR RGHTALGSPKYSFSTLESRKSSTAGRQRQRFARKSSLPLENAGVNTPGSSVGMVGLGL CRAESFPVLLDCSHGAGIILGESPAGGGAGGGSAGGGAVAIAQILNDSVADRSGCIQA GDRIVAINKMYSLDAGAMRQLLEGGSGRGGAGNNSGTPPANWLELEIEFDMPDAVVPA SGVFSVKLLRAGKCGLGLSVSGSSHGGLVISDVKMGSPAHRSGSLRSGDILLAVDQHP VQHFNVDALLKEQQNPSSSASSASSDFTTLTIKRIVLPDFLPMSSPIYSNCPPMAMGM GGMGVSSSSTDHDLYSSAYVTAGKYADCVSLKSRTPQPDYFRVPSMDDASLQSVQLRS GSGCSGNGGSRGVNEAGNGWSTAGVNSRSFGAASNQLPNTQSLTTELPEEEDEQEQLY PGYELNRYASVDCTALPPPMENKVYGSAASSSSKSSGSSLHQIIFTVRLEPKGGLLGI TLAGSEDITKPITISGLVEGGIAHKNGQIHVSDQLLAIDEHSVQGMPLSHATSLLQNL GDLVDLKILRSHDLANGSHLPQTQAIYAKVQRRPRSPSANTEASKESGNGNSNGCGAG SNGNGGNGKPRVFHVTLYKDKVYDDYGFSVSDGLYERGVFINRIRSGGPADMCGLLKP FDRIMQVNEMKTQDFDCCLTVPLIAAAGDKIEMIMQRTE" misc_feature 520..768 /gene="Grip" /note="canonical PDZ domain; Region: PDZ_canonical; cl49608" /db_xref="CDD:483948" misc_feature order(550..564,604..606,613..615,697..699,709..711, 718..723) /gene="Grip" /note="peptide binding site [polypeptide binding]; other site" /db_xref="CDD:467153" misc_feature 817..1074 /gene="Grip" /note="PDZ domain 2 of glutamate receptor-interacting protein 1 (GRIP1) and GRIP2, and related domains; Region: PDZ2_GRIP1-2-like; cd06681" /db_xref="CDD:467169" misc_feature order(853..873,901..903,910..912,1000..1002,1012..1014, 1021..1026) /gene="Grip" /note="peptide binding site [polypeptide binding]; other site" /db_xref="CDD:467169" misc_feature 1108..1431 /gene="Grip" /note="canonical PDZ domain; Region: PDZ_canonical; cl49608" /db_xref="CDD:483948" misc_feature order(1147..1167,1258..1260,1267..1269,1363..1365, 1375..1377,1384..1389) /gene="Grip" /note="peptide binding site [polypeptide binding]; other site" /db_xref="CDD:467153" misc_feature <1750..2247 /gene="Grip" /note="periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037" /db_xref="CDD:273938" misc_feature 1981..>2136 /gene="Grip" /note="canonical PDZ domain; Region: PDZ_canonical; cl49608" /db_xref="CDD:483948" misc_feature 2791..3045 /gene="Grip" /note="PDZ domain 6 of glutamate receptor-interacting protein 1 (GRIP1) and GRIP2, and related domains; Region: PDZ6_GRIP1-2-like; cd06683" /db_xref="CDD:467171" misc_feature order(2830..2850,2884..2886,2893..2895,2983..2985, 2995..2997,3004..3009) /gene="Grip" /note="peptide binding site [polypeptide binding]; other site" /db_xref="CDD:467171" misc_feature 3217..3474 /gene="Grip" /note="PDZ domain 7 of glutamate receptor-interacting protein 1 (GRIP1) and GRIP2, and related domains; Region: PDZ7_GRIP1-2-like; cd06685" /db_xref="CDD:467173" misc_feature order(3262..3282,3313..3315,3322..3324,3412..3414, 3424..3426,3433..3438) /gene="Grip" /note="peptide binding site [polypeptide binding]; other site" /db_xref="CDD:467173" misc_feature order(3382..3384,3391..3393,3406..3408,3415..3420, 3427..3432) /gene="Grip" /note="GRASP-1 binding site [polypeptide binding]; other site" /db_xref="CDD:467173" ORIGIN 1 tgttccgcgg acgtgcgcgc atcgttcagg ttcagtcgca tcgcagtcgc cgtcgcaggc 61 gttgaatttc ggaatttccc aatttccatt ggaaagcgaa ttgattttga aatcccccct 121 cgatttcgaa ctgtgcaatt attatttttt ttatttttaa tccttttttt ttttactgtg 181 aaaatgccaa atctgccatg agttgtggaa aatcgtaaag atcgcgtttt cccacttttt 241 ttggatggga agtggcagaa aagaaaactc aaaatgaaac tgtggaaatc aaagaagccc 301 attgtgggct gtgtgcctgg aaaatcggcg gccctcaaac aggaccaaca gcagcaacaa 361 caacaacagc agcaacagga gtcgcacaac agctccttca atggacatca tcatccgccg 421 acggacaccg ccttggcgcc catgttatcc gtggaccggg cgatgagtcc ggcgcaatcg 481 gaggactccg gattggcacc ggaaagggga accacctacg ccaccatcac tctgccacgg 541 aatgccctgc atttggccat cacattcgca gaacgcaacg atctttctta tccgccggtg 601 gttggatctc tgagtcccgt gggccatgcg gcggatttct tggcgcccgg cgatcgcctt 661 catcagatcg atggaatctc gacgattggc ttgagcaacc agaaggtgat gaacatgctc 721 tgcgctggag gatcggatgc gggtcctgcc atcgtggaga tcgagtactc gctgcccgaa 781 tacacagttt cccagaacag cctctgtgtg acctcgaagc tggcgcagat caccgtggag 841 cgggaaagtg gatgcctggg cctgacgctg aggggcgggg ccgactatcc gctgatcgtc 901 acccatgtga ggccccatgg acccgtctat aagaccggtc gcatcaagcc cggcgatcgc 961 ttgttgcgcg tcgataatgt ctcacttatt ggcaaaacgc tggcagaggc gcaacagatc 1021 atcaagtgcg gcggtcatgt ttccgggtat accaacctga ccatcgagta cgatgtttcc 1081 gtggtgcaga gcgttgagtt ctcgatggga ccgctgatca tcgagatcga gcggccgatg 1141 aacgataagt tgggcctggt actttgcaac tatacgccgg cgatggccgc ttccggttcc 1201 ggttcgagta cgccatccag tggggagaag atcgaggaat cgacgggcgt ctttatagcc 1261 agcatcctgc ccgctagcat tgcagatcgt tgcggcgcct tatccgtcgg cgatcaggtg 1321 ctctccatcg acgacacaat gatcgagcac accgccttca gtcccgacga ggtgatgacc 1381 atattggaca ccagcacggg tcgcggctac acgcagatgc agatcatgcc cgctcacgcg 1441 ttggcccgtc gcggacacac ggcattgggc agtcccaagt acagctttag caccctggag 1501 tcccgcaaat cctcgacggc gggtcgccag cgtcagcgtt tcgcccgcaa gagttccctg 1561 ccgctggaga atgcaggggt caacactccg ggatcctcgg tgggcatggt gggtctgggc 1621 ctctgccgcg ccgagagctt tcccgttctc ctcgactgca gccacggagc gggcattatc 1681 ctgggggaat ctccagcagg aggaggagca ggaggaggat ctgccggcgg aggagctgtg 1741 gccattgccc agatcctcaa cgattcggtg gccgatcgca gtggctgcat tcaggcgggc 1801 gatcgcattg tggccatcaa caagatgtac agcctggatg cgggggccat gaggcagctg 1861 ctcgagggag gatcgggtcg cggaggagca ggaaacaact cgggaacgcc gccggccaat 1921 tggctggagc tggagatcga gttcgatatg ccggatgccg tggtgcctgc cagtggtgtc 1981 tttagtgtca agctgctgag ggccggcaaa tgtggattgg gactgagtgt gagtggctcc 2041 agccatggcg gcctggtcat ttcggacgtc aagatgggca gtccggcgca tcgcagcggc 2101 tctttgagat cgggcgacat cctgctggcc gtcgaccagc atccagtgca gcatttcaat 2161 gtggacgcac tgctcaagga gcagcagaat ccctcatcct ccgcgtcctc cgcctcctcg 2221 gatttcacca cgctcaccat caagcggatc gtcctgcccg acttcctgcc catgtccagt 2281 cccatctaca gcaattgccc accgatggcc atgggaatgg gcggcatggg tgtctcgtcc 2341 agcagcacgg atcacgatct gtatagcagc gcctatgtga cggcgggcaa gtacgccgac 2401 tgcgtctccc tgaagtcgcg gactccgcag ccggactact tccgggtgcc cagcatggac 2461 gacgccagtc tgcagtcggt gcagctgcgt tccggatcgg ggtgctcggg gaatggcggc 2521 agtcgagggg tcaacgaggc aggcaacggc tggtccaccg ccggcgtcaa cagccgatcc 2581 tttggggcag ccagcaacca actgcccaac acccagagcc tgaccaccga gctgcccgag 2641 gaggaggacg aacaggagca gctgtatccc ggctacgagc tcaatcgcta tgccagtgtg 2701 gactgcaccg ccctgccgcc gcccatggag aacaaggtct acggatcggc ggccagttcg 2761 agcagcaaga gcagcgggag cagcctgcac cagatcatct tcacggtgcg tctggagccc 2821 aaggggggac tgctgggcat cactctggct ggcagcgagg atatcaccaa gcccatcacg 2881 atcagtggtc tcgtggaggg tggcattgcg cacaagaatg gccagatcca tgtgagtgac 2941 cagctgctgg ccatcgacga gcactcggtg cagggcatgc ccctttcgca tgccaccagt 3001 ctgctgcaga atctcggcga tctggtggac ctgaagatcc tgcggagtca cgatctggcc 3061 aacggcagtc atctgccgca gacgcaggcc atttacgcga aggtccagcg gcgtccgcgg 3121 agtccttcgg cgaatacgga ggccagcaag gagtcgggga atggaaatag caacggatgt 3181 ggagctggca gtaatggcaa tggcggaaat ggaaagcccc gcgtcttcca tgtcaccctg 3241 tacaaggaca aggtgtacga cgactatggc ttctcggttt ccgatggact ctacgagcgg 3301 ggcgtcttca tcaacaggat tcgcagtggc gggccggcgg atatgtgcgg tctcctgaag 3361 cccttcgatc gcattatgca ggttaacgaa atgaagacgc aggactttga ttgctgcctt 3421 actgttccgc tgatcgccgc cgccggcgat aaaatcgaga tgatcatgca gcgcacagag 3481 tgatcctcag tgtgcgcgat ccttatgtta aactagttgt acgctaagct aatcctaagt 3541 gccattgcta gcccataata ttatatacga tatcccctcc gtattctgta ttctgtatgc 3601 tgtactcctt accgaacgaa acgtaatcca cgaaacagaa agataaacac caaccttcaa 3661 ggacaataag ctctctaaac aacagtctgc cataaccaaa aaatgtcctc tatttaatat 3721 aaatctgcca taattttaca ttaattctac gctaaatttg tttcctagca aataaataat 3781 cataccgaca gtttgtttca aactaaacaa tcaagaacta tgagtaattt cattgc