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LOCUS XM_017145981 3695 bp mRNA linear INV 09-DEC-2024 transcript variant X8, mRNA. ACCESSION XM_017145981 VERSION XM_017145981.3 DBLINK BioProject: PRJNA1194641 KEYWORDS RefSeq. SOURCE Drosophila takahashii ORGANISM Drosophila takahashii Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_091683) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 9, 2024 this sequence version replaced XM_017145981.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_030179915.1-RS_2024_12 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 12/07/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3695 /organism="Drosophila takahashii" /mol_type="mRNA" /strain="IR98-3 E-12201" /db_xref="taxon:29030" /chromosome="X" /sex="female" /tissue_type="Whole fly" /dev_stage="Adult fly" /collected_by="Originally obtained from EHIME-Fly" gene 1..3695 /gene="HDAC6" /note="histone deacetylase 6; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 2 Proteins" /db_xref="GeneID:108060320" CDS 675..3569 /gene="HDAC6" /codon_start=1 /product="histone deacetylase 6 isoform X8" /protein_id="XP_017001470.2" /db_xref="GeneID:108060320" /translation="MSPPIVTRRSAQQAKIQTRAMASKSKGAAGATAATAAGVIGGGG GSSAGGGSGGISAADPRKANKPSAALLEAKRRARNMLKNQSNVMQECVTDIFQNAVDC KGAVRKPTALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLAERCLELPSRSA TKEEILRLHTEEHFERLKQTSGIRDDERMEDLSSRYDSIYIHPSTFELSLLATGSTIE LVDHLIAGKAQNGMAIIRPPGHHAMKAEFNGYCFFNNVALAAQHALDVHKLQRILIID YDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLQESDYHAIGSGAGRGYNFNVPL NAIGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLL NPLLRLADSRVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPRLVEVLPLPRPELTQAL LSCIAVHRTHWRCLQLQRTYDSKELLDQEKAQTDLHKLLRLWIGGPPPVDRYPTRDTA IPLPPEKLARNAARLQVLRTETKLSLPAVRVCYSYDAQMLLHCNLDDPGHPEQPSRVQ HIHKMHEEYGLLARMKQLAPRAATTDEVCLAHTRSHVNSVRRLMGRDPEELHRVAAGY NSVYLHPRTFDCATLAAGAVLQAVDSVLRGESRHGICNVRPPGHHAEQDQPHGFCIFN NVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFEANPKVLYISLHRYEHGAFFPKG PDGNYDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGF DAAIGDPLGGCKVTPEGYGLLTHWLSALAGGRIVVCLEGGYNVNSISYAMTMCTKTLL GDPVPTPQLGAVALQKPPTVAHQSCVESLQSCLEIQRSHWRSLEFVGRRLPAGDCVGE NNNEDFLTASLRQLNISNDDAPGAAGGAAGDRNACGDERPSGSKPKVKQQ" misc_feature 1041..2057 /gene="HDAC6" /note="Histone deacetylase 6, domain 1 and histone deacetylase 10; Region: HDAC10_HDAC6-dom1; cd10002" /db_xref="CDD:212526" misc_feature order(1392..1397,1419..1424,1506..1508,1512..1514, 1785..1787,1899..1901) /gene="HDAC6" /note="putative active site [active]" /db_xref="CDD:212526" misc_feature 2301..3374 /gene="HDAC6" /note="Histone deacetylase 6, domain 2; Region: HDAC6-dom2; cd10003" /db_xref="CDD:212527" misc_feature order(2676..2681,2703..2708,2790..2792,2796..2798, 3069..3071,3183..3185) /gene="HDAC6" /note="putative active site [active]" /db_xref="CDD:212527" ORIGIN 1 tttgctcggg atttctggtt caggttctga ttgcacgtgt gtgtgcgtgt ggtgtgccta 61 tgtatctgtg ctgttgctgc atcttcgtct gctcaaataa aaaaatcacg aatgcaactg 121 caacgttttt gaaaatcaaa cgaaaagccg ccagctaaag tccaattttg ttactcagtg 181 ttttaagtat taagtagtgc aagcagccga caaacaaaaa gtacatatat caaaaggaaa 241 aacaacaaca tcgaatgcag agcaactgaa gcgcaaacac acacaaacaa acaagcagta 301 gggattgtga gagcgagata gaaataaact aggcataatt tatagcgcac acaaaataaa 361 aaagaaggct aattataaga gaaaagtgtg cgactcggaa tcgataaata acgggactaa 421 aggagtgaga ggtgagccgg gaaatttgtt tggaacaaac ggtatataat acacaacagc 481 gaagaagaag aagtgggagg ggaagaacaa caacaagcag ctgtgaatca gtccgtcccg 541 ctcccccacg ccccccgctt gctgctgctg ctgctgcttc ctcttcctac gccggatatt 601 cggatttgga ttcggaatcg gattcggatt tggttttcgg ttggttttcc aattcggact 661 cgtttaccca caacatgagc ccgcccatcg tcacgcgacg gagcgcgcag caggccaaga 721 ttcagacgcg ggcaatggcc agtaagtcga agggagcggc gggagcgacg gcggcgacgg 781 cggccggggt gatcggcggc ggcggcggct cctctgccgg cggcggcagc ggcggtatca 841 gtgccgccga tccgcgaaag gcgaacaaac cgagcgcagc gctcttggag gcgaaacgtc 901 gagcgcggaa catgctcaag aaccagagca acgtcatgca ggagtgcgtc acggatatat 961 tccagaatgc tgtcgattgc aagggcgctg tgcgaaagcc cacggccctc atctacgacg 1021 agtcgatgag ccagcactgc tgtttgtggg acaaggagca ctacgagtgc cccgagcgct 1081 tcacacgcgt cctggagcgc tgccgcgaac tgaatctggc ggagcgctgc ttggagttgc 1141 cctcgcgatc ggccaccaag gaggagattc tgcggctgca cacggaggag cactttgagc 1201 gcctgaagca gacctcgggg attcgtgatg acgagcgcat ggaggacctg agctcccgct 1261 acgattcaat ctacattcat ccgtccacat tcgagctttc cctgctggcc accggatcca 1321 ccatcgagtt ggtggaccat ctgatcgctg gaaaggccca gaatggcatg gccatcatcc 1381 ggccgccggg tcatcatgcc atgaaggccg agttcaatgg ctattgcttc ttcaacaacg 1441 tggccctggc cgcccagcac gccctggatg tccacaagct gcagcgcatc ctgatcatcg 1501 actacgacgt ccatcatgga cagggaacgc agaggttctt ctacaacgat cccagggtgg 1561 tctacttctc gatccatcgc ttcgagcacg gcagcttctg gccgcacctg caggagtcgg 1621 attaccatgc catcggatcg ggagcgggca ggggctacaa cttcaatgtg cccctgaatg 1681 cgattgggat gacgaacggc gattacctgg ccattttcca gcagctcctg ctgccggtgg 1741 ccctggagtt tcagccggag ctgattatcg tttcggctgg ctacgatgcg gccctcggtt 1801 gtccggaggg cgaaatggag gtgacgccgg cctgctatcc gcatctgctc aatcccctcc 1861 tgcgactcgc cgactcgcgg gtggccgtcg tcctggaggg cggctattgc ctggactcgc 1921 tggccgaggg tgccgctttg accctgcgct ccctgctcgg cgatccctgc ccccgactgg 1981 tggaggtact gcctctgccg cgtcccgaac tcacgcaggc gctgctcagc tgcattgccg 2041 tccatcggac gcactggcgc tgcctgcagc tgcagcgaac ctatgattcg aaggagttgc 2101 tcgaccagga gaaggctcaa acggacctac acaagctgct gcgcctttgg ataggcggac 2161 caccgccagt ggatcgttat cccaccaggg atactgctat tcctctgccc cccgagaagc 2221 tggccaggaa tgcggcccgt ctgcaggtcc tccgcaccga aacaaagcta tcgttgcccg 2281 cggtgagagt ctgctactcg tacgacgccc agatgctgct ccactgcaat ctcgacgatc 2341 ccggccatcc ggagcagcca tcgcgcgtcc agcacatcca caagatgcac gaggagtacg 2401 gcctgctggc caggatgaag cagctagcgc cgagggcggc caccaccgat gaagtttgcc 2461 tggcccacac gcgatcgcat gtgaattcgg tgcgtcgact gatgggacgc gacccggagg 2521 aactgcatcg cgtggcggcg ggctacaatt cggtgtatct gcatccgcgc accttcgatt 2581 gcgccacctt ggccgccggc gccgtgctcc aggcggtgga cagtgtgctg cgcggcgagt 2641 cgcggcacgg catctgcaac gttcgtccgc cgggccatca tgccgagcag gatcagccgc 2701 atggcttctg tatcttcaac aatgtggcca ttgcggcgca gtatgctatc agggattttg 2761 gtttggaacg tgtgcttatt gtcgattggg atgtgcatca cggcaacggg acgcagcaca 2821 tcttcgaggc gaatcccaag gtgctttaca taagccttca tcgctacgag catggagcct 2881 tctttcccaa gggacccgac ggcaactacg atgtggtggg caagggagcc ggacggggat 2941 tcaatgtgaa tataccctgg aataagaagg gcatgggtga tttggagtac gctctggcct 3001 tccagcaact gatcatgccc attgcctacg agttcaaccc gcaactggtc ctggtctccg 3061 cgggcttcga tgcggccatc ggcgatccgc tgggcggctg caaggtgacg cccgagggct 3121 acggcctgct cacccattgg ctctctgcgc tggccggcgg caggattgtc gtctgcctgg 3181 agggtggcta caatgtaaac tccatttcgt atgccatgac catgtgcacc aagacgctac 3241 tgggcgatcc ggtgccgacg ccccagctgg gtgcagtggc tctgcagaag ccgccgacgg 3301 tggcccatca gagctgcgtg gaatcgctgc agtcgtgcct ggagattcaa cgcagccact 3361 ggcggagctt ggagtttgtg ggccgacggt tgccggccgg cgattgtgtg ggcgagaata 3421 acaacgagga ttttcttacc gcctccttgc gacagttgaa tatctcaaat gacgacgcac 3481 cgggggcggc gggcggcgcg gccggcgatc ggaacgcttg cggcgatgag cggcccagcg 3541 gcagcaagcc caaagtcaag cagcaataga cagcggggcg gcgtgcagcg tttgcggatc 3601 gacgggggag aactgggtgt gtctgggctg ccggctggtg ggctgcggtc gctacatggg 3661 cggccacatg gagctgcact cggcggaggc acagc