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LOCUS XM_017140600 7724 bp mRNA linear INV 09-DEC-2024 transcript variant X1, mRNA. ACCESSION XM_017140600 VERSION XM_017140600.3 DBLINK BioProject: PRJNA1194641 KEYWORDS RefSeq. SOURCE Drosophila takahashii ORGANISM Drosophila takahashii Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_091683) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 9, 2024 this sequence version replaced XM_017140600.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_030179915.1-RS_2024_12 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 12/07/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..7724 /organism="Drosophila takahashii" /mol_type="mRNA" /strain="IR98-3 E-12201" /db_xref="taxon:29030" /chromosome="X" /sex="female" /tissue_type="Whole fly" /dev_stage="Adult fly" /collected_by="Originally obtained from EHIME-Fly" gene 1..7724 /gene="beta-Spec" /note="spectrin beta chain; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 2 Proteins" /db_xref="GeneID:108056695" CDS 346..7272 /gene="beta-Spec" /codon_start=1 /product="spectrin beta chain isoform X1" /protein_id="XP_016996089.1" /db_xref="GeneID:108056695" /translation="MTTDISIVRWDPSQGPGNEYIDEYEYDGGNSSSRLFERSRIKAL AEERESVQKKTFTKWVNSHLCRVNCRIADLYVDMRDGKHLIKLLEVLSGERLPKPTKG KMRIHCLENVDKALQFLREQRVHLENIGSHDIVDGNASLNLGLIWTIILRFQIQDITI EEVDNKETKSAKDALLLWCQMKTAGYHNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQF EKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFVEHPDEKSIITYVVTYYHYFSKL KQETVQGKRIGKVVGIAMENDKMVHDYEHFTSDLLKWIETTIQSLGEREFENSLAGVQ GQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQKPYTPKEGKMISDINKAW ERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQDNFGFDL AAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRKDNVMRLWTY LLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMGVEDLLQKH SLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSRVQQLEDAYAELVRLA VERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKALES EITSHDPQLQNVAKVGAELITEGHFGADRIKDRLKEILSKWDHLLDLTKYRRQRLENA VEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVID ALHKQAESLKLNEAEKAAVDKRLEAIDSRYRELTELAKLRKQRLLDALSLYKLMSEAD GVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLLH VEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKK RILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKII RERISQIEQIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTP TSLPEAEKLLTQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNA LKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQA ENQLKRHEAFLTTMEANDDKINTLLQVADTLVEKDHFDAEKIGKRAENITGRRDDNRQ RALDQHDKLKNQVKLHEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFE AEIAANKERLFEAEKSAQELSKEKPEFKDVIEPKLKELAKQFEDLEVHTKEKGAMLFD ANREVLVQQTCDDIDSYITDLEKQIVSGDTANDLTSVNILMQKQQVIQTQMAVKARQV EEIDKQTEYLQKTVPEEKIEPIVVKKTAVLERFEKIKAPLLERQKALEKKKEAFQFCR DVEDEKLWIDEKLPVANSPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRK LIDEGHEDAKKFEALISDLTQKWQELKDAIEGRRRHLLESEKVQQYFFDAQEAESWMS EQELYMMVEDRGKDEISAQNLMKKHENLEQSVEDYANTIRQLGEVARQFSGDDISSGD AVAVKQSQLDKLYAGLKDLAGERRARLNEALQLFMLSREVDDLEQWITDREVVAGSQE LGQDFDHVTLLSERFNEFARDTEAVGGERVAKVNGIADNLIQAGHSDSATIAEWKDNL NESWQDLLELIETRTQMLAASRELHKFFHDCKDVLGRILEKQHGVSDELGRDAGSVST LQRKHYNFLQDLTTLYSQVQQIQEESAKLQDAYAGDKAKEITNREQEVLHAWDNLQAM CDARKQKLADTGDLFRFFNMVRILMIWMEDLVRQMNTSEKPRDVSGVELLMNNHQSLK AEIDTREDNFGACISLGKELLTRNHYASADIKDRLMSLSNSRNALLRRWEERWENLQL ILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTIDEVENLIKKHEAFEKSAAAQEERF SALERLTTFELKEMKRRQELAEEAERQRIKEEQEAKAASEAAEQAKREAERRDDVDVG ASHDDSAAKDTAVEFERVVEIQTERGATPGAGEGHEGYVTRKHEWDSTTKKASNRSWD KVYMAARAGRISFYKDQKGYKSNPELTFRGEPSYDLQNAAIEIASDYTKKKHVLRVKL ANGALFLLQAHDDTEMSQWVTSLKAQSDSTAVAASRSQTLPATSQKDEPKRRSFFTLK KK" misc_feature 451..801 /gene="beta-Spec" /note="first calponin homology (CH) domain found in the beta-I spectrin-like subfamily; Region: CH_SPTB-like_rpt1; cd21246" /db_xref="CDD:409095" misc_feature order(454..456,463..468,475..480,487..492,499..501, 661..663,670..675,682..684,703..705,718..744,763..768, 772..777,784..789,796..801) /gene="beta-Spec" /note="actin binding site [polypeptide binding]; other site" /db_xref="CDD:409095" misc_feature 850..1164 /gene="beta-Spec" /note="second calponin homology (CH) domain found in the beta-I spectrin-like subfamily; Region: CH_SPTB_like_rpt2; cd21248" /db_xref="CDD:409097" misc_feature order(856..858,868..870,1018..1020,1024..1029,1036..1038, 1057..1059,1072..1098,1123..1128,1132..1137,1144..1149, 1156..1158) /gene="beta-Spec" /note="putative actin binding site [polypeptide binding]; other site" /db_xref="CDD:409097" misc_feature 1237..1569 /gene="beta-Spec" /note="Spectrin repeat; Region: Spectrin; pfam00435" /db_xref="CDD:395348" misc_feature 1570..1587 /gene="beta-Spec" /note="linker region [active]" /db_xref="CDD:238103" misc_feature 1609..1908 /gene="beta-Spec" /note="Spectrin repeats; Region: SPEC; smart00150" /db_xref="CDD:197544" misc_feature 1918..2565 /gene="beta-Spec" /note="Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cd00176" /db_xref="CDD:238103" misc_feature 2245..2262 /gene="beta-Spec" /note="linker region [active]" /db_xref="CDD:238103" misc_feature 2260..2883 /gene="beta-Spec" /note="Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cd00176" /db_xref="CDD:238103" misc_feature 2563..2580 /gene="beta-Spec" /note="linker region [active]" /db_xref="CDD:238103" misc_feature 2887..3519 /gene="beta-Spec" /note="Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cd00176" /db_xref="CDD:238103" misc_feature 3196..3213 /gene="beta-Spec" /note="linker region [active]" /db_xref="CDD:238103" misc_feature 3208..3852 /gene="beta-Spec" /note="Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cd00176" /db_xref="CDD:238103" misc_feature 3517..3534 /gene="beta-Spec" /note="linker region [active]" /db_xref="CDD:238103" misc_feature 3853..4485 /gene="beta-Spec" /note="Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cd00176" /db_xref="CDD:238103" misc_feature 4165..4182 /gene="beta-Spec" /note="linker region [active]" /db_xref="CDD:238103" misc_feature 4501..4797 /gene="beta-Spec" /note="Spectrin repeats; Region: SPEC; smart00150" /db_xref="CDD:197544" misc_feature 4807..5442 /gene="beta-Spec" /note="Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cd00176" /db_xref="CDD:238103" misc_feature 5119..5136 /gene="beta-Spec" /note="linker region [active]" /db_xref="CDD:238103" misc_feature 5125..5763 /gene="beta-Spec" /note="Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cd00176" /db_xref="CDD:238103" misc_feature 5437..5454 /gene="beta-Spec" /note="linker region [active]" /db_xref="CDD:238103" misc_feature 5764..6390 /gene="beta-Spec" /note="Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cd00176" /db_xref="CDD:238103" misc_feature 6076..6093 /gene="beta-Spec" /note="linker region [active]" /db_xref="CDD:238103" misc_feature 6397..>6579 /gene="beta-Spec" /note="Spectrin repeat; Region: Spectrin; pfam00435" /db_xref="CDD:395348" misc_feature 6844..7167 /gene="beta-Spec" /note="Beta-spectrin pleckstrin homology (PH) domain; Region: PH_beta_spectrin; cd10571" /db_xref="CDD:269975" misc_feature order(6865..6867,6904..6912,7054..7056) /gene="beta-Spec" /note="non-cannonical phosphoinositide binding site [chemical binding]; other site" /db_xref="CDD:269975" polyA_site 7724 /gene="beta-Spec" /experiment="COORDINATES: polyA evidence [ECO:0006239]" ORIGIN 1 gcctccgctt ctcactcgtt cgcaacgcga tgttttgaat acatacattt tttccattct 61 cgccaagaaa gttcacccgc cagaccgaag attttagtga acgcgctaaa tcgtgaaatt 121 aactgtgttt tgtgaatcaa ttagggcgga cggagctgca aaattgtcga gtagtgattc 181 tcttctgaag gcaacacaga cattcggttt ggactcaagg ataaataaaa cgacgaacgg 241 aggagtggcg agctccctga aaataaaaca cacgacacga aactcacgaa aactagacaa 301 tagaaagtac aactaatcca ctgtggaagc aatagatccc cagccatgac gacggacatt 361 tcgattgttc gctgggatcc cagccagggt cctggcaacg agtacatcga tgagtacgag 421 tacgatggcg gcaactcctc gtcgcgcctc ttcgagcgct ccaggatcaa ggcgctggcc 481 gaggagcgtg agagtgtcca gaagaagacc ttcaccaagt gggtgaactc tcatctctgc 541 cgcgtcaact gccgcattgc cgatctgtat gtggatatgc gggatggcaa gcatctgatc 601 aagctgctcg aggtcctttc cggcgaacga ctgcccaagc ccaccaaggg caagatgagg 661 atccattgcc tggagaatgt ggacaaggca ctgcagtttc tacgcgaaca gcgcgtccat 721 ctggagaaca ttggctccca tgacatagtc gatggcaatg cctcgttgaa cttgggcctc 781 atttggacca tcatcctgcg cttccagatc caggacatca ccatcgagga ggtggacaac 841 aaggagacca agtcggccaa ggatgctttg cttctttggt gccagatgaa gactgccggc 901 tatcataatg tcaatgtgcg taactttacc acctcttggc gcgatggcct ggcctttaat 961 gcgattattc acaaacaccg tccggatttg gttcaattcg agaagctctc gaagaccaat 1021 gccattcaca atctgaacaa tgccttcgat gtggccgagg ataagctcgg tctggccaag 1081 ctgctcgatg ccgaggatgt tttcgttgag catcccgacg agaagtccat catcacgtat 1141 gtcgtgacct actatcacta cttcagcaag ctcaaacagg agacggtgca gggcaagcgc 1201 attggcaagg tggtgggcat tgccatggag aacgacaaga tggtccatga ctatgagcat 1261 ttcaccagtg atttgctcaa gtggatagag accaccatcc aatccctggg tgagcgggag 1321 tttgagaact cgctggcagg agttcagggt caattggctc agttttccaa ctatcgcacc 1381 atcgagaagc cgcccaagtt tgtggagaag ggcaatctgg aggttctcct gttcaccctg 1441 cagtccaaga tgcgggccaa caatcagaaa ccctacacgc ccaaggaggg caagatgatc 1501 tcggacatta acaaggcctg ggagcgattg gagaaggccg aacatgagcg cgagttggct 1561 ttgcgcgagg agctcatccg gcaggagaag ctggagcagc tggccgctcg tttcgatcgc 1621 aaggcttcca tgcgcgagac ttggctgtcg gagaatcagc gtttggttag ccaggataac 1681 tttggtttcg atctcgccgc tgttgaggcg gcggccaaga agcacgaggc catcgaaacg 1741 gacatctttg cctacgagga gcgtgttcaa gcggtggtcg ccgtttgcga tgagttggaa 1801 tcagagcgct atcacgatgt gaagcgcatt ctcctgcgca aggacaatgt gatgcgtttg 1861 tggacttatc tgctggagtt gctgcgtgcc aggcgtatgc gtctggagat ctcgctgcag 1921 ctgcagcaga acttccagga gatgctctac atactggaca acatggagga gatcaagcag 1981 ctgctgatga ccgacgacta tggcaagcat ctgatgggcg tggaggatct gctgcagaag 2041 cattcgctgg tcgaagcaga cattaatatc ctgggggaga gggtcaaagt ggtcgtgcag 2101 aactcgcaga agttccttag cgacgatccc gagtcgtaca aaccctgcga tcccgagatt 2161 atcgtctcgc gcgtccagca actggaggat gcctatgcgg agctagtgcg tctggctgtc 2221 gaacgacgca gtcgcctgga ggagagccgc aaactgtggc agttctactg ggacaccgcc 2281 gacgaggaga actggatcaa ggagaaggag cagatcgtgt ccaccgatga ggtgggtcac 2341 gacctcacca ccgtcaatct gatgctcagc aagcacaagg ctttggagtc ggagatcacc 2401 tcgcatgatc cccagctgca aaatgtggcc aaggtgggcg cagaactgat cacagagggt 2461 catttcggag ccgatcgcat caaggatcgc ttgaaggaga tcctctccaa gtgggatcac 2521 ctgttggacc tcaccaaata tcgccgccag cgactggaga atgccgtcga gtatttccaa 2581 ctgttcgccg atgccgacga cgtggacaac tggatgctgg acaccctgcg catcgtttca 2641 tccgaggatg tgggacgcga tgaggccaat gttcaatcgc tgctcaagaa gcacaaggac 2701 gtagcggatg agctaaagaa ctatgccgag gtaatcgacg ctctgcacaa acaggccgag 2761 agtctcaagc tcaacgaggc ggagaaggcg gcggtggaca agcgactgga ggccatcgac 2821 agtcggtaca gggagctcac cgagctggcc aagttgcgca agcagcgact ccttgatgcc 2881 cttagccttt acaaactaat gtccgaagcg gacggcgtgg agcaatggat caaggagaag 2941 accaagatgc tggacacgat gacgccgggc aaggatatcg aggatgtgga aataatgaag 3001 catcgcttcg agggcttcga caaggaaatg aatgccaatg cttcccgcgt ggcagtggtt 3061 aatcaactgg ctcgtcagct gcttcatgtt gagcatccga actcggatga gattctggag 3121 cggcagaatc atctcaacca ggagtggtcg acgctgcgcg agaaggccga ggccaaaatg 3181 gatgatttga agtccgccca tggcgttcag accttctaca tcgagtgccg cgagacgatc 3241 tcgtggattg aggacaagaa gcgcatcctg accgaaacgg atagcttgga aatggatttg 3301 actggtgtga tgactttgca gcgtcgcttg agcggaatgg atcgcgattt agcggccatt 3361 caggccaagc tttcgagctt ggaacgcgag gccaacagca ttgaggatga gcatcccgag 3421 gaggccaaga tcatcaggga gcgcatctcg cagatcgaac agatctggga gcagctcacc 3481 cagatgctca aggagcgcga ctcgaagttg gaggaggcgg gcgatctgca tcgcttcctg 3541 cgcgatctcg atcacttcca gacctggctc accaagaccc aaacggatgt ggcgtccgag 3601 gatacaccca cttcgctgcc ggaagctgag aagctgctca cccagcacca atcgattcgc 3661 gaggagattg acaactacac cgaggactac aagaacatga tggagtacgg cgagcggctg 3721 acctccgagg gcagcacctc cgacgatccg cagtacatgt tcctaaggga gcgattgaat 3781 gcgctgaagg atggctggga ggagctgcat cagatgtggg agaacaggca agtgctcctc 3841 tctcaaagcc tcgatcagca gctcttcaat cgcgatgcca ggcaaacgga ggtgctgctc 3901 agccagcagg agcacttcct cagcaaggac gatacaccgg ttaatctcga gcaggccgag 3961 aatcagctga agcggcacga ggccttcctc accaccatgg aggctaacga tgataagatc 4021 aatacgctgc tccaggtggc cgatacgctg gtggagaagg atcactttga cgcggagaag 4081 attggcaagc gggcggagaa tatcacaggg cgaagggatg acaacaggca gagggctttg 4141 gatcagcatg ataagctcaa aaaccaagtc aagctgcacg aattcctgca ggatcttgag 4201 gagctggccg agtgggtgca ggagaagtat gccacgtcgc aggatgagtc gtacaggagc 4261 gccaagacta ttcactccaa gtggacgcgt catcaggcct tcgaggcgga gattgcggcc 4321 aacaaggagc gcctgttcga ggccgagaaa tccgcccagg agctgtccaa ggagaagccc 4381 gagttcaagg acgtgatcga accgaaactc aaggaactgg ccaagcagtt tgaggatctg 4441 gaggtgcaca ccaaggagaa gggcgccatg ctgttcgacg ccaatcgcga ggtgctcgtc 4501 cagcagacct gcgacgacat cgattcctac atcacggatc tcgagaagca gattgtcagt 4561 ggcgatacag cgaatgattt gacctccgtc aacattctga tgcaaaagca gcaggttatc 4621 cagacacaga tggctgtaaa ggcacgccag gtggaggaga ttgacaagca gacggagtat 4681 ctccagaaga ccgtgcccga ggagaagatc gaaccgattg tggttaagaa gacggcggtc 4741 ctggagagat tcgagaagat caaggcgccg ctgttggagc ggcaaaaggc gctggagaag 4801 aagaaggagg ccttccagtt ctgtcgcgat gtcgaggacg agaagctctg gatcgacgag 4861 aagctgccgg tggccaactc acctgactat ggcaattccc tgttcaatgt ccatgtgctg 4921 aagaagaaga accaatcgct ggccaccgaa atcgacaacc atgagccgcg catcaatgcc 4981 atttgcaaca atggacgcaa actgatcgac gagggtcacg aggatgccaa gaagttcgag 5041 gcgctgatta gcgatctcac ccagaagtgg caggagctca aggatgccat cgagggcagg 5101 cggaggcatc tcctggagtc cgagaaggtg cagcagtact tcttcgatgc ccaggaggcc 5161 gagtcgtgga tgagcgagca ggaactctac atgatggtcg aggatcgcgg caaggatgag 5221 attagtgccc agaatctgat gaagaagcac gagaacctgg agcaatcggt ggaggattac 5281 gctaatacca ttcgtcagct gggcgaggtg gctcgccagt ttagcggcga tgatatctcc 5341 tccggcgatg ccgttgccgt caagcaatcg cagctggaca agctgtatgc cggactcaag 5401 gatttggctg gtgagagaag ggctcgtctc aacgaagccc tccagctatt catgcttagc 5461 cgcgaggtgg acgacctaga gcaatggata acggatcgcg aggtggtcgc cggttcgcag 5521 gaattgggtc aggactttga ccatgtcact ttgctttccg agcgcttcaa tgagttcgcc 5581 cgcgacacgg aggccgttgg aggcgaaagg gtggccaagg tcaacggaat agccgacaat 5641 ctcattcagg cgggccattc cgattcggcc accatagccg aatggaagga taacctgaat 5701 gaatcgtggc aggatctact ggagttgatt gagacacgca cccagatgct cgctgcctcg 5761 cgggagctgc acaagttctt ccacgactgc aaggatgtcc tgggaaggat cctcgagaag 5821 cagcacggcg tgtccgatga actgggacgc gatgcgggct ccgtttcgac gctgcagcga 5881 aagcattaca atttcctgca ggatctgacc acgctgtact cgcaggtcca gcagatacag 5941 gaggagtcgg ccaagctgca ggatgcctat gccggggaca aggccaagga gatcaccaat 6001 cgggagcagg aggtcctgca tgcctgggac aatctgcagg caatgtgcga tgcgcgcaaa 6061 cagaagctag ccgatacggg cgatctcttc cggttcttca atatggtacg cattctgatg 6121 atctggatgg aggatctagt gcgccagatg aacacctccg agaagccacg cgatgtttcc 6181 ggcgtggagc tgctgatgaa caaccaccag agtttgaagg ccgagatcga tacgcgggag 6241 gataacttcg gggcgtgcat ctcgctgggc aaggagctgc tcaccaggaa tcactacgcg 6301 tccgcggata tcaaggatcg cctgatgtcg ctgagcaaca gccggaatgc cctgctccgc 6361 cgatgggagg agcgctggga gaatctccag ctgattctgg aggtgtacca attcgcccga 6421 gatgctgccg ttgccgaggc ctggctgatc gcccaggagc cctacctgct ctcctcggag 6481 ctcggccaca ccatcgacga ggtggagaac ctgatcaaga agcacgaggc ctttgagaag 6541 tcagccgccg cccaagagga gcgcttcagt gcccttgagc gtttgacaac atttgagctt 6601 aaggagatga agaggcgcca ggagctggcg gaggaggcgg agcgacagcg catcaaggag 6661 gagcaggagg ccaaggccgc ttcggaggcg gcggaacagg ccaaacgaga ggctgagcga 6721 cgcgacgacg tggacgttgg agcctcgcac gatgattcag ccgccaaaga cacggccgtc 6781 gagttcgagc gcgttgtcga gatccaaaca gaacgaggcg caactccagg cgccggcgag 6841 ggtcacgagg gctatgtgac acgaaaacac gagtgggact cgaccaccaa gaaggcctcc 6901 aaccgatctt gggataaggt atacatggct gccagggccg gacgcatttc gttctacaaa 6961 gatcagaagg gttacaagag taatcccgaa ttgaccttcc gcggcgagcc cagctacgat 7021 ctgcaaaacg ctgccattga aattgccagt gattacacca agaagaagca cgtgctgcga 7081 gtcaagctcg caaacggcgc cttgttcttg ctgcaggccc atgacgacac cgagatgtcc 7141 cagtgggtga cctccctgaa ggcccagagc gactcgacag cggtggccgc cagcagatcc 7201 cagactctgc cagccacctc acaaaaggac gaaccaaagc gcagatcgtt ttttacttta 7261 aagaaaaagt aaactaacac ccccctttcg taaccgcaac actttaagca agagcagcta 7321 attaaaacaa aaacaaaatg agaaggctaa aagatgatga gaaaaatgat aatacaaaac 7381 aagcgacaac aaattataca gcaaaaatta agaagaagca aatatatatt tttttttcat 7441 atatttaaaa cttatttcgt aatgagagga aaacaaaaaa caaaaaaccg acaaaaactt 7501 gcaagagaag agacgagcaa aacgtaaaca attattatgc ttatcaaatt tgcacgataa 7561 atactgctat tatgattaaa cgtatgtatc ttatttattt aaacaaatac aaagtaatat 7621 aaagataaaa aaaaatacaa aaaacaaaca aaaaatttga ggaaaccaac tcgtgtatgc 7681 atttcaatgt attcgataaa taaacgaaat attcctttaa agta