PREDICTED: Drosophila takahashii Death associated molecule related

LOCUS       XM_017138869            1106 bp    mRNA    linear   INV 09-DEC-2024
            to Mch2 caspase (Damm), mRNA.
ACCESSION   XM_017138869
VERSION     XM_017138869.3
DBLINK      BioProject: PRJNA1194641
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Dec 9, 2024 this sequence version replaced XM_017138869.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Drosophila takahashii"
                     /mol_type="mRNA"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     gene            1..1106
                     /gene="Damm"
                     /note="Death associated molecule related to Mch2 caspase;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 Protein"
                     /db_xref="GeneID:108055501"
     CDS             28..993
                     /gene="Damm"
                     /codon_start=1
                     /product="caspase-3"
                     /protein_id="XP_016994358.3"
                     /db_xref="GeneID:108055501"
                     /translation="MDTEQQEQPAENEEVQENSTEEGEAPSTDGESSERFQPASMTFK
                     WDGEIAETIVGDGKEPPKEFQPFSMVFQVDAVGEIVSSASVPLEAAYGPHPRLQPPIV
                     CIFNHTFHGNEKKVRHGSEKDVEALFKTFGNLKCQVEEVKDPKKSDIKEKIANLSLKN
                     FNHLSGVVIVILSHGGRKEKIETCDQQFYDLDDDVLFPLFRNKTLIGKPKILIVQACK
                     DYMHRLQADSSIIDPVHSYYIKCYSTSEGLQSFRHTLEGSFYIQALCNEMDQHALTKD
                     FKAIVEDVNVKVQNDCEKTGKQQVPAITVSAWTPFCFGDYVEHVS"
     misc_feature    337..945
                     /gene="Damm"
                     /note="Caspase, interleukin-1 beta converting enzyme (ICE)
                     homologues; Cysteine-dependent aspartate-directed
                     proteases that mediate programmed cell death (apoptosis).
                     Caspases are synthesized as inactive zymogens and
                     activated by proteolysis of the peptide...; Region: CASc;
                     cl00042"
                     /db_xref="CDD:444667"
     misc_feature    order(376..378,550..552,670..672,772..789,799..804)
                     /gene="Damm"
                     /note="substrate pocket [chemical binding]; other site"
                     /db_xref="CDD:237997"
     misc_feature    order(547..549,676..678)
                     /gene="Damm"
                     /note="active site"
                     /db_xref="CDD:237997"
     polyA_site      1106
                     /gene="Damm"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 ctgagaatac acaaattagt cttagcaatg gacacggagc agcaagaaca gccggcggaa
       61 aatgaagagg tccaagaaaa ttcaacggaa gaaggtgagg cgcccagcac tgatggcgag
      121 tcctctgaaa gatttcagcc tgcctcaatg acctttaaat gggacggtga gattgcggaa
      181 acaattgtcg gtgatggaaa agaacccccc aaggaattcc aaccttttag tatggttttt
      241 caggtcgatg ctgtcgggga gatagtctcc agtgcttcag ttccactgga agccgcctat
      301 ggtcctcatc caagattgca gccaccaatc gtctgcatat tcaatcacac tttccatggg
      361 aacgaaaaaa aggtacggca tggaagcgaa aaggatgtcg aagcgttgtt caaaaccttc
      421 ggcaatctaa aatgtcaggt ggaagaagtt aaggatccca aaaaatccga cattaaggag
      481 aaaattgcga atttatctct aaaaaatttc aaccacctgt ctggtgtggt catcgtcatc
      541 ttgagccatg gcggccgaaa agagaagatc gaaacgtgcg accaacaatt ttacgacttg
      601 gatgacgatg ttctgtttcc actcttcaga aataaaaccc taatcggcaa gccgaaaatc
      661 ctaatagtcc aggcgtgcaa ggactacatg catagactgc aagcggattc ttcgataatt
      721 gatccagttc actcatacta tatcaaatgc tacagcactt ccgagggttt gcaaagcttt
      781 cgccacacac ttgagggttc gttttacata caagccttgt gcaatgaaat ggatcaacat
      841 gcccttacca aggacttcaa ggcaattgtt gaggatgtaa acgtgaaggt ccaaaatgat
      901 tgtgaaaaaa ccggaaaaca acaagtacca gcaataactg tgtcagcatg gacaccattc
      961 tgctttggag attatgtgga gcacgtttct tagaggattg gatggcggat ttataacaag
     1021 aacactttct ccatgcaact acacctgaca actacatttt tctgtcgcct cttcggagga
     1081 aataaagaac aaatggatga ctaaga