translation initiation factor IF-2 [Escherichia coli].

LOCUS       WP_240812433             726 aa            linear   BCT 03-JUN-2024
ACCESSION   WP_240812433
VERSION     WP_240812433.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 726)
  AUTHORS   Roy,B., Liu,Q., Shoji,S. and Fredrick,K.
  TITLE     IF2 and unique features of initiator tRNAfMet help establish the
            translational reading frame
  JOURNAL   RNA Biol 15 (4-5), 604-613 (2018)
   PUBMED   28914580
REFERENCE   2  (residues 1 to 726)
  AUTHORS   Sacerdot,C., Vachon,G., Laalami,S., Morel-Deville,F., Cenatiempo,Y.
            and Grunberg-Manago,M.
  TITLE     Both forms of translational initiation factor IF2 (alpha and beta)
            are required for maximal growth of Escherichia coli. Evidence for
            two translational initiation codons for IF2 beta
  JOURNAL   J Mol Biol 225 (1), 67-80 (1992)
   PUBMED   1374802
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00487.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..726
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..726
                     /gene="infB"
     Protein         1..726
                     /product="translation initiation factor IF-2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003743 - translation initiation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /calculated_mol_wt=78796
     Region          <6..>117
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          150..200
                     /region_name="IF2_N"
                     /note="Translation initiation factor IF-2, N-terminal
                     region; pfam04760"
                     /db_xref="CDD:428110"
     Region          224..725
                     /region_name="InfB"
                     /note="Translation initiation factor IF-2, a GTPase
                     [Translation, ribosomal structure and biogenesis];
                     COG0532"
                     /db_xref="CDD:440298"
ORIGIN      
        1 mtknaqaeka rreqeaaelk rkaeeearrk leeearrvae earrmaeenk wtdnaepted
       61 ssdyhvttsq harqaedesd reveggrgrg rnakaarpkk gnkhaeskad reearaavrg
      121 gkggkrkgss lqqgfqkpaq avnrdvvige titvgelank mavkgsqvik ammklgamat
      181 inqvidqeta qlvaeemghk vilrrenele eavmsdrdtg aaaeprapvv timghvdhgk
      241 tslldyirst kvasgeaggi tqhigayhve tengmitfld tpghaaftsm rargaqatdi
      301 vvlvvaaddg vmpqtieaiq hakaaqvpvv vavnkidkpe adpdrvknel sqygilpeew
      361 ggesqfvhvs akagtgidel ldaillqaev lelkavrkgm asgaviesfl dkgrgpvatv
      421 lvregtlhkg divlcgfeyg rvramrnelg qevleagpsi pveilglsgv paagdevtvv
      481 rdekkareva lyrqgkfrev klarqqkskl enmfanmteg evhevnivlk advqgsveai
      541 sdsllklstd evkvkiigsg vggitetdat laaasnailv gfnvradasa rkvieaesld
      601 lryysviynl idevkaamsg mlspelkqqi iglaevrdvf kspkfgaiag cmvtegvvkr
      661 hnpirvlrdn vviyegeles lrrfkddvne vrngmecgig vknyndvrtg dvievfeiie
      721 iqrtia