Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]
LOCUS WP_211180484 799 aa linear BCT 01-JUL-2024 coli]. ACCESSION WP_211180484 VERSION WP_211180484.1 KEYWORDS RefSeq. SOURCE Escherichia coli ORGANISM Escherichia coli Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. REFERENCE 1 (residues 1 to 799) AUTHORS Charpentier,X., Chalut,C., Remy,M.H. and Masson,J.M. TITLE Penicillin-binding proteins 1a and 1b form independent dimers in Escherichia coli JOURNAL J Bacteriol 184 (13), 3749-3752 (2002) PUBMED 12057973 REFERENCE 2 (residues 1 to 799) AUTHORS Chalut,C., Remy,M.H. and Masson,J.M. TITLE Disulfide bridges are not involved in penicillin-binding protein 1b dimerization in Escherichia coli JOURNAL J Bacteriol 181 (9), 2970-2972 (1999) PUBMED 10217796 REFERENCE 3 (residues 1 to 799) AUTHORS Vollmer,W., von Rechenberg,M. and Holtje,J.V. TITLE Demonstration of molecular interactions between the murein polymerase PBP1B, the lytic transglycosylase MltA, and the scaffolding protein MipA of Escherichia coli JOURNAL J Biol Chem 274 (10), 6726-6734 (1999) PUBMED 10037771 REFERENCE 4 (residues 1 to 799) AUTHORS Zijderveld,C.A., Aarsman,M.E., den Blaauwen,T. and Nanninga,N. TITLE Penicillin-binding protein 1B of Escherichia coli exists in dimeric forms JOURNAL J Bacteriol 173 (18), 5740-5746 (1991) PUBMED 1885547 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF007061.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK09506 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..799 /organism="Escherichia coli" /db_xref="taxon:562" gene 1..799 /gene="mrcB" Protein 1..799 /product="bifunctional glycosyl transferase/transpeptidase" /EC_number="2.4.99.28" /GO_component="GO:0009274 - peptidoglycan-based cell wall [Evidence IEA]" /GO_function="GO:0008658 - penicillin binding [Evidence IEA]" /GO_function="GO:0008955 - peptidoglycan glycosyltransferase activity [Evidence IEA]" /GO_process="GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]" /GO_process="GO:0046677 - response to antibiotic [Evidence IEA]" /calculated_mol_wt=88759 Region 20..798 /region_name="mrcB" /note="bifunctional glycosyl transferase/transpeptidase; Reviewed; PRK09506" /db_xref="CDD:236544" ORIGIN 1 mprkgkgkgk grkprgkrgw lwlllklaiv favliaiygv yldqkirsri dgkvwqlpaa 61 vygrmvnlep dmtisknemv klleatqyrq vskmtrpgef tvqansiemi rrpfdfpdsk 121 egqvrarltf dgdhlativn mennrqfgff rldprlitmi sspngeqrlf vprsgfpdll 181 vdtllatedr hfyehdgisl ysigravlan ltagrtvqga stltqqlvkn lflssersyw 241 rkaneaymal imdaryskdr ilelymnevy lgqsgdneir gfplaslyyf grpveelsld 301 qqallvgmvk gasiynpwrn pklalerrnl vlrllqqqqi idqelydmls arplgvqprg 361 gvispqpafm qlvrqelqak lgdkvkdlsg vkifttfdsv aqdaaekaav egipalkkqr 421 klsdletaiv vvdrfsgevr amvggsepqf agynramqar rsigslakpa tyltalsqpk 481 iyrlntwiad apialrqpng qvwspqnddr rysesgrvml vdaltrsmnv ptvnlgmalg 541 lpavtetwik lgvpkdqlhp vpamllgaln ltpievaqaf qtiasggnra plsalrsvia 601 edgkvlyqsf pqaeravpaq aayltlwtmq qvvqrgtgrq lgakypnlhl agktgttnnn 661 vdtwfagidg stvtitwvgr dnnqptklyg asgamsiyqr ylanqtptpl nlvppediad 721 mgvdydgnfv csggmrilpv wtsdpqslcq qsemqqqpsg npfdqssqpq qqpqqqpaqq 781 eqkdsdgvag wikdmfgsn