type III secretion system effector zinc metalloprotease NleC

LOCUS       WP_115801843             339 aa            linear   BCT 10-JUL-2019
            [Escherichia coli].
ACCESSION   WP_115801843
VERSION     WP_115801843.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 339)
  AUTHORS   Giogha,C., Lung,T.W., Muhlen,S., Pearson,J.S. and Hartland,E.L.
  TITLE     Substrate recognition by the zinc metalloprotease effector NleC
            from enteropathogenic Escherichia coli
  JOURNAL   Cell. Microbiol. 17 (12), 1766-1778 (2015)
   PUBMED   26096513
REFERENCE   2  (residues 1 to 339)
  AUTHORS   Yen,H., Ooka,T., Iguchi,A., Hayashi,T., Sugimoto,N. and Tobe,T.
  TITLE     NleC, a type III secretion protease, compromises NF-kappaB
            activation by targeting p65/RelA
  JOURNAL   PLoS Pathog. 6 (12), e1001231 (2010)
   PUBMED   21187904
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR006155
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..339
                     /gene="nleC"
     Protein         1..339
                     /product="type III secretion system effector zinc
                     metalloprotease NleC"
                     /calculated_mol_wt=38125
     Region          33..283
                     /region_name="Peptidase_M85"
                     /note="NFkB-p65-degrading zinc protease; pfam13678"
                     /db_xref="CDD:372668"
ORIGIN      
        1 micrvldinm kipslqsnfn fsapagysap iapnraenay adyvldigkr iplsaadlsn
       61 vyesviravh dsrsrlidqh tvdmigntvl dalsrsqtfr davsygihne kvhigcikyr
      121 neyelneess vkiddiqslt cnelyeydvg qepifpicea gendneepyv sfsvapdtds
      181 yempswqegl iheiihhvtg ssdpsgdsni elgpteilar rvaqelgwsv pdfkgyaepe
      241 reahlrlrnl nalrqaamrh eeneraffer lgtisdryea spdfteysav snigygfiqq
      301 hdfpglaind nlqdanqiql yhgapyiftf gdvdkhnqq