Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

thiamine pyrophosphate-dependent enzyme [Salmonella enterica].


LOCUS       WP_071892921             269 aa            linear   BCT 26-AUG-2024
ACCESSION   WP_071892921
VERSION     WP_071892921.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 269)
  AUTHORS   Arjunan,P., Umland,T., Dyda,F., Swaminathan,S., Furey,W., Sax,M.,
            Farrenkopf,B., Gao,Y., Zhang,D. and Jordan,F.
  TITLE     Crystal structure of the thiamin diphosphate-dependent enzyme
            pyruvate decarboxylase from the yeast Saccharomyces cerevisiae at
            2.3 A resolution
  JOURNAL   J Mol Biol 256 (3), 590-600 (1996)
   PUBMED   8604141
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF014794.5
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF02775.26
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Salmonella enterica"
                     /db_xref="taxon:28901"
     Protein         1..269
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /calculated_mol_wt=30519
     Region          <1..269
                     /region_name="IolD"
                     /note="TPP-dependent trihydroxycyclohexane-1,2-dione
                     (THcHDO) dehydratase, myo-inositol metabolism
                     [Carbohydrate transport and metabolism]; COG3962"
                     /db_xref="CDD:443162"
ORIGIN      
        1 maevervyav eysgegfkpe iedhmdtqkv feefneitrs wltqtrvlgv lnrmlpenal
       61 vvaaagslpg dlqrvwqsrg endyhveygy scmgyevnaa lgaklaqper evysfvgdgs
      121 fmmlhselvt svqmgkkitv illdnmtngc innlqmehgm dsyftefrfh qqesgrqegg
      181 fipvdfaria egygcksyrv ttieqlheal edarkqtvst lidikvlpkt mvhkylswwr
      241 vggaqvsrse riqavarmle ehigqarqy