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1-deoxy-D-xylulose-5-phosphate synthase [Vibrio fluvialis].


LOCUS       WP_020431382             621 aa            linear   BCT 28-FEB-2022
ACCESSION   WP_020431382
VERSION     WP_020431382.1
KEYWORDS    RefSeq.
SOURCE      Vibrio fluvialis
  ORGANISM  Vibrio fluvialis
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 621)
  AUTHORS   Lois,L.M., Campos,N., Putra,S.R., Danielsen,K., Rohmer,M. and
            Boronat,A.
  TITLE     Cloning and characterization of a gene from Escherichia coli
            encoding a transketolase-like enzyme that catalyzes the synthesis
            of D-1-deoxyxylulose 5-phosphate, a common precursor for
            isoprenoid, thiamin, and pyridoxol biosynthesis
  JOURNAL   Proc Natl Acad Sci U S A 95 (5), 2105-2110 (1998)
   PUBMED   9482846
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00204.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Vibrio fluvialis"
                     /db_xref="taxon:676"
     gene            1..621
                     /gene="dxs"
     Protein         1..621
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=67636
     Region          7..620
                     /region_name="Dxs"
                     /note="Deoxyxylulose-5-phosphate synthase [Coenzyme
                     transport and metabolism, Lipid transport and metabolism];
                     COG1154"
                     /db_xref="CDD:440768"
ORIGIN      
        1 mtldiskypt lalantpdel rsmpkevlpt lcdelrtyll nsvsqssghl asglgtvelt
       61 valhyvyntp fdqliwdvgh qayphkiltg rreqmptirq kgglhpfpwr eeseydtlsv
      121 ghsstsisaa lgmaicagke gqnrkvvsvi gdgaitagma feamnhagdv hpdmlvilnd
      181 nemsisenvg alnnhlaqll sgnlytsire ggkkvlsgvp pikelvrrte ehlkgmvvpg
      241 tlfeelgfny igpvdghdvl eltktlknmr elkgpqflhv mtkkgkgyep aekdpigyhg
      301 vpkfdpshds lpkststkpt fskifgdflc dmaaqdpklm aitpamregs gmvrfskeyp
      361 sqyfdvaiae qhavtlatgm aiaghqpiva iystflqrgy dqlihdvaim dlpvmfaidr
      421 aglvgadgqt hqgafdlsfm rcipnmvima padenecrqm lytghqhqgp savryprgng
      481 mgvtiesdft aleigkgrim regekvails fgtllpyale aaqalnatva dmrfvkplde
      541 alisemanth dvlvtleenv vaggagggvv efmmkhklik pvlnlglpdr fiaqgtqeem
      601 hqelgldaag ieravrdyla k