UDP-2,3-diacylglucosamine diphosphatase [Vibrio fluvialis].

LOCUS       WP_020430072             243 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_020430072
VERSION     WP_020430072.1
KEYWORDS    RefSeq.
SOURCE      Vibrio fluvialis
  ORGANISM  Vibrio fluvialis
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 243)
  AUTHORS   Babinski,K.J., Kanjilal,S.J. and Raetz,C.R.
  TITLE     Accumulation of the lipid A precursor UDP-2,3-diacylglucosamine in
            an Escherichia coli mutant lacking the lpxH gene
  JOURNAL   J Biol Chem 277 (29), 25947-25956 (2002)
   PUBMED   12000771
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01854.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..243
                     /organism="Vibrio fluvialis"
                     /db_xref="taxon:676"
     gene            1..243
                     /gene="lpxH"
     Protein         1..243
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /EC_number="3.6.1.54"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008758 - UDP-2,3-diacylglucosamine
                     hydrolase activity [Evidence IEA]"
                     /GO_function="GO:0016462 - pyrophosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=28062
     Region          1..239
                     /region_name="PRK05340"
                     /note="UDP-2,3-diacylglucosamine hydrolase; Provisional"
                     /db_xref="CDD:235420"
     Site            order(8,10,41,79..80,114,195,197)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:277343"
     Site            order(8,10,41,79,114,195,197)
                     /site_type="other"
                     /note="putative metal binding site [ion binding]"
                     /db_xref="CDD:277343"
ORIGIN      
        1 mhtlfisdlh ltpnrpdith cftqfmrsea tkadalyvlg dlfdfwigdd dptlfaeqik
       61 qefkhltsng vpcyfihgnr dfligrrfak etgvtlldee avvdlygtsa vilhgdtlct
      121 edvrylafre kvhqpwlqwi fnrlpyfikk rivakiqtdi rsdknqkame imdvtpdevv
      181 hvmdkygvdl mihghthrpa ihqvndgsqk trivlgdwyt qgsvlvysnn gyslenrrfe
      241 sql