MULTISPECIES: AI-2E family transporter [Vibrio].

LOCUS       WP_020331136             357 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_020331136
VERSION     WP_020331136.1
KEYWORDS    RefSeq.
SOURCE      Vibrio
  ORGANISM  Vibrio
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
REFERENCE   1  (residues 1 to 357)
  AUTHORS   Khera,R., Mehdipour,A.R., Bolla,J.R., Kahnt,J., Welsch,S.,
            Ermler,U., Muenke,C., Robinson,C.V., Hummer,G., Xie,H. and
            Michel,H.
  TITLE     Cryo-EM structures of pentameric autoinducer-2 exporter from
            Escherichia coli reveal its transport mechanism
  JOURNAL   EMBO J 41 (18), e109990 (2022)
   PUBMED   35698912
REFERENCE   2  (residues 1 to 357)
  AUTHORS   Rettner,R.E. and Saier,M.H. Jr.
  TITLE     The autoinducer-2 exporter superfamily
  JOURNAL   J Mol Microbiol Biotechnol 18 (4), 195-205 (2010)
   PUBMED   20559013
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10001851
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Vibrio"
                     /db_xref="taxon:662"
     Protein         1..357
                     /product="AI-2E family transporter"
                     /GO_function="GO:0015562 - efflux transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=39474
     Region          17..357
                     /region_name="PerM"
                     /note="Predicted PurR-regulated permease PerM [General
                     function prediction only]; COG0628"
                     /db_xref="CDD:440393"
ORIGIN      
        1 mfemvsrwyk rrfsdphavs lvailffgfi tiyffghlia pllvaivlay llewpvvqlc
       61 rmkiprtlsv ilviliftgl mllavfglvp tiwqqivnlv ndipnmyngl qkfiatlper
      121 ypelanlqiv esiminaknk algmgesvvk gslaslvsia tlavylilvp llvffllkdk
      181 qemlsmvrgv lprnrklatk vwdemnqqis nyirgkvlei livggvsyvt faildlrysv
      241 llavavgfsv lipyigaaav tvpvaivglf qwgmtppfyy lliaygiiqa ldgnvlvpvl
      301 fseavnlhpv aiivavlvfg glwgfwgvff aiplatlvka vwnalpsiee eppqpna