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4-hydroxy-tetrahydrodipicolinate reductase [Vibrio cholerae].


LOCUS       WP_019828671             269 aa            linear   BCT 29-APR-2021
ACCESSION   WP_019828671
VERSION     WP_019828671.1
KEYWORDS    RefSeq.
SOURCE      Vibrio cholerae
  ORGANISM  Vibrio cholerae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 269)
  AUTHORS   Scapin,G., Reddy,S.G., Zheng,R. and Blanchard,J.S.
  TITLE     Three-dimensional structure of Escherichia coli dihydrodipicolinate
            reductase in complex with NADH and the inhibitor
            2,6-pyridinedicarboxylate
  JOURNAL   Biochemistry 36 (49), 15081-15088 (1997)
   PUBMED   9398235
REFERENCE   2  (residues 1 to 269)
  AUTHORS   Pavelka,M.S. Jr., Weisbrod,T.R. and Jacobs,W.R. Jr.
  TITLE     Cloning of the dapB gene, encoding dihydrodipicolinate reductase,
            from Mycobacterium tuberculosis
  JOURNAL   J Bacteriol 179 (8), 2777-2782 (1997)
   PUBMED   9098082
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00036.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Vibrio cholerae"
                     /db_xref="taxon:666"
     gene            1..269
                     /gene="dapB"
     Protein         1..269
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /EC_number="1.17.1.8"
                     /GO_function="GO:0008839 -
                     4-hydroxy-tetrahydrodipicolinate reductase [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /calculated_mol_wt=28443
     Region          2..264
                     /region_name="DapB"
                     /note="4-hydroxy-tetrahydrodipicolinate reductase [Amino
                     acid transport and metabolism]; COG0289"
                     /db_xref="CDD:440058"
ORIGIN      
        1 mvriaiagaa grmgrnlvka thqnplselg agserpessl vgvdigelcg igkqgivlvd
       61 nleqaveqfd viidftapas tlanlalceq hgkklvigtt gftdaqcqtf eqaakkipiv
      121 mapnysvgvn lvfkllekaa kvmgdycdie iveahhrhkv dapsgtaigm geaiahamgn
      181 qlsdvavyar egitgersrn eigfatirag diigehtamf adigerveit hkatdrmtfa
      241 ngavkaaiwl aeqpagfytm tdvlglndl