UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase

LOCUS       WP_017420729             387 aa            linear   BCT 19-JUN-2019
            [Vibrio vulnificus].
ACCESSION   WP_017420729
VERSION     WP_017420729.1
KEYWORDS    RefSeq.
SOURCE      Vibrio vulnificus
  ORGANISM  Vibrio vulnificus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 387)
  AUTHORS   McNally,D.J., Hui,J.P., Aubry,A.J., Mui,K.K., Guerry,P.,
            Brisson,J.R., Logan,S.M. and Soo,E.C.
  TITLE     Functional characterization of the flagellar glycosylation locus in
            Campylobacter jejuni 81-176 using a focused metabolomics approach
  JOURNAL   J. Biol. Chem. 281 (27), 18489-18498 (2006)
   PUBMED   16684771
REFERENCE   2  (residues 1 to 387)
  AUTHORS   Schoenhofen,I.C., Lunin,V.V., Julien,J.P., Li,Y., Ajamian,E.,
            Matte,A., Cygler,M., Brisson,J.R., Aubry,A., Logan,S.M., Bhatia,S.,
            Wakarchuk,W.W. and Young,N.M.
  TITLE     Structural and functional characterization of PseC, an
            aminotransferase involved in the biosynthesis of pseudaminic acid,
            an essential flagellar modification in Helicobacter pylori
  JOURNAL   J. Biol. Chem. 281 (13), 8907-8916 (2006)
   PUBMED   16421095
REFERENCE   3  (residues 1 to 387)
  AUTHORS   Schoenhofen,I.C., McNally,D.J., Vinogradov,E., Whitfield,D.,
            Young,N.M., Dick,S., Wakarchuk,W.W., Brisson,J.R. and Logan,S.M.
  TITLE     Functional characterization of dehydratase/aminotransferase pairs
            from Helicobacter and Campylobacter: enzymes distinguishing the
            pseudaminic acid and bacillosamine biosynthetic pathways
  JOURNAL   J. Biol. Chem. 281 (2), 723-732 (2006)
   PUBMED   16286454
REFERENCE   4  (residues 1 to 387)
  AUTHORS   Obhi,R.K. and Creuzenet,C.
  TITLE     Biochemical characterization of the Campylobacter jejuni Cj1294, a
            novel UDP-4-keto-6-deoxy-GlcNAc aminotransferase that generates
            UDP-4-amino-4,6-dideoxy-GalNAc
  JOURNAL   J. Biol. Chem. 280 (21), 20902-20908 (2005)
   PUBMED   15790564
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03588.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Vibrio vulnificus"
                     /db_xref="taxon:672"
     gene            1..387
                     /gene="pseC"
     Protein         1..387
                     /product="UDP-4-amino-4,
                     6-dideoxy-N-acetyl-beta-L-altrosamine transaminase"
                     /EC_number="2.6.1.92"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /calculated_mol_wt=42931
     Region          2..384
                     /region_name="PseC"
                     /note="UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine
                     transaminase; TIGR03588"
                     /db_xref="CDD:274662"
     Site            order(54..55,157,160,183,187..188,329)
                     /site_type="active"
                     /note="inhibitor-cofactor binding pocket [active]"
                     /db_xref="CDD:99740"
     Site            order(54..55,79,157,160,183,188)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99740"
     Site            188
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99740"
ORIGIN      
        1 mipygkqdin qqdidsvvev lnsdfltqgp qvpafeqali ehtgasyala vnsatsalhi
       61 aclalglgeg dwlwtspitf vasancglyc gaqvdfvdid patynmcptr leeklikaqa
      121 egklpkvvvp vhlcgqpcdm vaiaklakqy nfkviedash aiggkyqglp ignceysdit
      181 vfsfhpvkiv ttaeggavit nqkalsdkma llrshgitrd peqmegeshg gwyyqqidlg
      241 fnyrmtelqa algvsqmqrl ddfvaarhhl adrynrllqs lpvvlpyqle ntysglhlyv
      301 irlqldkisl thkevfdalr gkgigvnlhy ipvhtqpyye kmgfstgnfp eseryyseai
      361 slpmfhsmte eqqdtvvqvl teilqer