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LOCUS WP_017037920 140 aa linear BCT 02-MAR-2025 ACCESSION WP_017037920 VERSION WP_017037920.1 KEYWORDS RefSeq. SOURCE Vibrio genomosp. F10 ORGANISM Vibrio genomosp. F10 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio. REFERENCE 1 (residues 1 to 140) AUTHORS Scott,J.W., Hawley,S.A., Green,K.A., Anis,M., Stewart,G., Scullion,G.A., Norman,D.G. and Hardie,D.G. TITLE CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations JOURNAL J Clin Invest 113 (2), 274-284 (2004) PUBMED 14722619 REFERENCE 2 (residues 1 to 140) AUTHORS Kemp,B.E. TITLE Bateman domains and adenosine derivatives form a binding contract JOURNAL J Clin Invest 113 (2), 182-184 (2004) PUBMED 14722609 REFERENCE 3 (residues 1 to 140) AUTHORS Janosik,M., Kery,V., Gaustadnes,M., Maclean,K.N. and Kraus,J.P. TITLE Regulation of human cystathionine beta-synthase by S-adenosyl-L-methionine: evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal region JOURNAL Biochemistry 40 (35), 10625-10633 (2001) PUBMED 11524006 REFERENCE 4 (residues 1 to 140) AUTHORS Zhang,R., Evans,G., Rotella,F.J., Westbrook,E.M., Beno,D., Huberman,E., Joachimiak,A. and Collart,F.R. TITLE Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase JOURNAL Biochemistry 38 (15), 4691-4700 (1999) PUBMED 10200156 REFERENCE 5 (residues 1 to 140) AUTHORS Ponting,C.P. TITLE CBS domains in CIC chloride channels implicated in myotonia and nephrolithiasis (kidney stones) JOURNAL J Mol Med (Berl) 75 (3), 160-163 (1997) PUBMED 9106071 REFERENCE 6 (residues 1 to 140) AUTHORS Bateman,A. TITLE The structure of a domain common to archaebacteria and the homocystinuria disease protein JOURNAL Trends Biochem Sci 22 (1), 12-13 (1997) PUBMED 9020585 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF012780.6 Evidence Source :: EMBL-EBI Source Identifier :: PF00571.33 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..140 /organism="Vibrio genomosp. F10" /db_xref="taxon:723171" Protein 1..140 /product="CBS domain-containing protein" /calculated_mol_wt=15860 Region 9..126 /region_name="CBS_pair_bac" /note="Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria; cd04630" /db_xref="CDD:341393" Site order(14,16..18,40..42,107,119,121,123..124) /site_type="other" /note="putative ligand binding site II [chemical binding]" /db_xref="CDD:341393" Region 14..80 /region_name="CBS repeat" /note="CBS repeat [structural motif]" /db_xref="CDD:341393" Site order(40,54,58..59,62,85,107..109,123) /site_type="other" /note="putative ligand binding site I [chemical binding]" /db_xref="CDD:341393" Region 85..126 /region_name="CBS repeat" /note="CBS repeat [structural motif]" /db_xref="CDD:341393" ORIGIN 1 mktheiiqvr dvmantyvmv dglttvneai alarqhnvka livnkrneed efgiilmndi 61 akkvlaknrs pmrtnvyeim tkpalsvapn mnvkycarlf erfkisrapv iengevigmv 121 synnivfngm aidderenrf