4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Enterovibrio

LOCUS       WP_017017175             314 aa            linear   BCT 10-AUG-2020
            norvegicus].
ACCESSION   WP_017017175
VERSION     WP_017017175.1
KEYWORDS    RefSeq.
SOURCE      Enterovibrio norvegicus
  ORGANISM  Enterovibrio norvegicus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Enterovibrio.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002188.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK01045
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Enterovibrio norvegicus"
                     /db_xref="taxon:188144"
     gene            1..314
                     /gene="ispH"
                     /gene_synonym="lytB"
     Protein         1..314
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=34554
     Region          1..301
                     /region_name="ispH"
                     /note="4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
                     Reviewed; PRK01045"
                     /db_xref="CDD:234893"
     Site            order(12,96,197)
                     /site_type="other"
                     /note="Fe-S cluster binding site [ion binding]"
                     /db_xref="CDD:260116"
     Site            order(15,40..41,73..74,124,126,167..168,224..227,269)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:260116"
     Site            order(124,126,225,227)
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:260116"
ORIGIN      
        1 mkillanprg fcagvdrais iveralemyq ppiyvrhevv hnrfvveglk srgavfveel
       61 sevpddsivi fsahgvsqav rneaksrslt vfdatcplvt kvhmevaras rknmevvlig
      121 haghpevegt mgqyasetgg mylvetaedv hainvkdpsn lhyvsqttls vdetadvidr
      181 lrevfpeiqg prkddicyat qnrqdavrel atqcdvmvvv gsknssnsnr lrelseklgt
      241 payltdcaed vkaewfeskv kvgvtagasa peelvnliia qieayggtav eelkgreenm
      301 ffevprelqv khid