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translation elongation factor 4 [Enterovibrio norvegicus].


LOCUS       WP_017011801             598 aa            linear   BCT 22-MAR-2021
ACCESSION   WP_017011801
VERSION     WP_017011801.1
KEYWORDS    RefSeq.
SOURCE      Enterovibrio norvegicus
  ORGANISM  Enterovibrio norvegicus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Enterovibrio.
REFERENCE   1  (residues 1 to 598)
  AUTHORS   Gibbs,M.R., Moon,K.M., Chen,M., Balakrishnan,R., Foster,L.J. and
            Fredrick,K.
  TITLE     Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis
            of the 30S subunit of the 70S ribosome
  JOURNAL   Proc Natl Acad Sci U S A 114 (5), 980-985 (2017)
   PUBMED   28096346
REFERENCE   2  (residues 1 to 598)
  AUTHORS   Song,G. and Qin,Y.
  TITLE     EF4 reveals the energy barrier for tRNA back-translocation in the
            peptidyl transferase center
  JOURNAL   RNA Biol 13 (10), 934-939 (2016)
   PUBMED   27472653
REFERENCE   3  (residues 1 to 598)
  AUTHORS   Kumar,V., Ero,R., Ahmed,T., Goh,K.J., Zhan,Y., Bhushan,S. and
            Gao,Y.G.
  TITLE     Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the
            Ribosome
  JOURNAL   J Biol Chem 291 (25), 12943-12950 (2016)
   PUBMED   27137929
REFERENCE   4  (residues 1 to 598)
  AUTHORS   Liu,H., Chen,C., Zhang,H., Kaur,J., Goldman,Y.E. and Cooperman,B.S.
  TITLE     The conserved protein EF4 (LepA) modulates the elongation cycle of
            protein synthesis
  JOURNAL   Proc Natl Acad Sci U S A 108 (39), 16223-16228 (2011)
   PUBMED   21930951
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01393.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..598
                     /organism="Enterovibrio norvegicus"
                     /db_xref="taxon:188144"
     gene            1..598
                     /gene="lepA"
     Protein         1..598
                     /product="translation elongation factor 4"
                     /EC_number="3.6.5.n1"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /calculated_mol_wt=65887
     Region          1..595
                     /region_name="LepA"
                     /note="Translation elongation factor EF-4, membrane-bound
                     GTPase [Translation, ribosomal structure and biogenesis];
                     COG0481"
                     /db_xref="CDD:440249"
ORIGIN      
        1 mkhirnfsii ahidhgkstl sdrliqvcgg lsdremaaqv ldsmdlerer gitikaqsvt
       61 lnytandget yqlnfidtpg hvdfsyevsr slaacegall vvdagqgvea qtlancytai
      121 emdlevvpvl nkidlpaadp drvaeeiedi vgidateavr csaktglgvd lvledivkni
      181 papegdpkap lqaliidswf dnylgvvslv rikhgelkkg dkikvmttgq vwgvdrigif
      241 tpkqkdtqgl rtgevgwvvc gikdilgapv gdtlthakng aeaalpgfkk vkpqvyaglf
      301 pissddyenf rdalgklsln daslfyepes saalgfgfrc gflgmlhmei iqerlereyd
      361 lelittaptv vyevkktngd ilyvdspakl pavndieimg epiarchilv pseylgnvit
      421 lcvekrgmqv dmvyhgkqva ltydipmaev vldffdrlks tsrgyasldy nfqryeasnm
      481 vrvdvllngd nvdalaiith kdhaqnrgrd lvekmkefip rqqfdiaiqa aigthiiars
      541 tvkqlrknvi akcyggdisr kkkllqkqkd gkkrmkqign velpqeafla ilhvgkdk