bifunctional indole-3-glycerol-phosphate synthase

LOCUS       WP_017011383             455 aa            linear   BCT 11-DEC-2019
            TrpC/phosphoribosylanthranilate isomerase TrpF [Enterovibrio
            norvegicus].
ACCESSION   WP_017011383
VERSION     WP_017011383.1
KEYWORDS    RefSeq.
SOURCE      Enterovibrio norvegicus
  ORGANISM  Enterovibrio norvegicus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Enterovibrio.
REFERENCE   1  (residues 1 to 455)
  AUTHORS   Eberhard,M. and Kirschner,K.
  TITLE     Modification of a catalytically important residue of
            indoleglycerol-phosphate synthase from Escherichia coli
  JOURNAL   FEBS Lett. 245 (1-2), 219-222 (1989)
   PUBMED   2494074
REFERENCE   2  (residues 1 to 455)
  AUTHORS   Priestle,J.P., Grutter,M.G., White,J.L., Vincent,M.G., Kania,M.,
            Wilson,E., Jardetzky,T.S., Kirschner,K. and Jansonius,J.N.
  TITLE     Three-dimensional structure of the bifunctional enzyme
            N-(5'-phosphoribosyl)anthranilate
            isomerase-indole-3-glycerol-phosphate synthase from Escherichia
            coli
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 84 (16), 5690-5694 (1987)
   PUBMED   3303031
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006945.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09427
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Enterovibrio norvegicus"
                     /db_xref="taxon:188144"
     gene            1..455
                     /gene="trpCF"
     Protein         1..455
                     /product="bifunctional indole-3-glycerol-phosphate
                     synthase TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /EC_number="4.1.1.48"
                     /EC_number="5.3.1.24"
                     /GO_function="GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=49608
     Region          1..455
                     /region_name="PRK09427"
                     /note="bifunctional indole-3-glycerol-phosphate synthase
                     TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /db_xref="CDD:236509"
ORIGIN      
        1 metvlakiva dkriwieark aaqplasfin evvpsdrsfy dalsgkpakf ileckkasps
       61 kglirddfdl dyiasvygnh aaaisvltde kyfqgnfdfl pqvrgqvpcp vlckdfmvdt
      121 yqvylarfhq adaillmlsv lnddeyrels alahelnlgv ltevsneeel eraialkakv
      181 vginnrnlrd lsidlnrtke laprlsedti visesgiyth qqvrglapfa ngfligsslm
      241 seddveravr rvlygdnkvc gltraedaka aydayanygg lifveksprf vdvdaarkvm
      301 egaplayvgv fqnhelsdva etanalslsa vqlhgnedgd yvkalrdalp sntqiwkahg
      361 vsdtapalea nadrnlfdsr vgtqsggtgq afdwsliped rkdtvmiagg lsqenakdaa
      421 qlgcagldfn sgvesapgik dkqkldaafs alrdy