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GTP cyclohydrolase II [Enterovibrio norvegicus].


LOCUS       WP_017009437             200 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_017009437
VERSION     WP_017009437.1
KEYWORDS    RefSeq.
SOURCE      Enterovibrio norvegicus
  ORGANISM  Enterovibrio norvegicus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Enterovibrio.
REFERENCE   1  (residues 1 to 200)
  AUTHORS   Ren,J., Kotaka,M., Lockyer,M., Lamb,H.K., Hawkins,A.R. and
            Stammers,D.K.
  TITLE     GTP cyclohydrolase II structure and mechanism
  JOURNAL   J Biol Chem 280 (44), 36912-36919 (2005)
   PUBMED   16115872
REFERENCE   2  (residues 1 to 200)
  AUTHORS   Ritz,H., Schramek,N., Bracher,A., Herz,S., Eisenreich,W.,
            Richter,G. and Bacher,A.
  TITLE     Biosynthesis of riboflavin: studies on the mechanism of GTP
            cyclohydrolase II
  JOURNAL   J Biol Chem 276 (25), 22273-22277 (2001)
   PUBMED   11301327
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10791939
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..200
                     /organism="Enterovibrio norvegicus"
                     /db_xref="taxon:188144"
     Protein         1..200
                     /product="GTP cyclohydrolase II"
                     /EC_number="3.5.4.25"
                     /GO_function="GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0009231 - riboflavin biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=22069
     Region          4..197
                     /region_name="ribA"
                     /note="GTP cyclohydrolase II RibA; PRK00393"
                     /db_xref="CDD:234745"
     Site            order(4..9,22,24..26,33,35,37,57,59..60,62..66,68,75..76,
                     79,91,93,101..102,105..106,108..109,112)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:238348"
     Site            order(53..58,60,69,71,74,94..97,104,108,111,117,129,131,
                     152..154,157)
                     /site_type="active"
                     /db_xref="CDD:238348"
ORIGIN      
        1 makvrarvpl kvgvgskisa eilsfeglns dkehvaiifk svdqqsgntp lvrmhseclt
       61 gdvfhssrcd cgeqleetiq kmgteggiil ylrqegrgig lynkldayel qsegmdtyqa
      121 nnhlgfpddl rtfedaaeml kaldvhsirl vtnnpkkire iqelgitlae vvgtkahikd
      181 gnenylkakv shghhkltie