UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase [Enterovibrio

LOCUS       WP_017006966             447 aa            linear   BCT 04-JUN-2024
            norvegicus].
ACCESSION   WP_017006966
VERSION     WP_017006966.1
KEYWORDS    RefSeq.
SOURCE      Enterovibrio norvegicus
  ORGANISM  Enterovibrio norvegicus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Enterovibrio.
REFERENCE   1  (residues 1 to 447)
  AUTHORS   Kouidmi,I., Levesque,R.C. and Paradis-Bleau,C.
  TITLE     The biology of Mur ligases as an antibacterial target
  JOURNAL   Mol Microbiol 94 (2), 242-253 (2014)
   PUBMED   25130693
REFERENCE   2  (residues 1 to 447)
  AUTHORS   Bertrand,J.A., Auger,G., Martin,L., Fanchon,E., Blanot,D., Le
            Beller,D., van Heijenoort,J. and Dideberg,O.
  TITLE     Determination of the MurD mechanism through crystallographic
            analysis of enzyme complexes
  JOURNAL   J Mol Biol 289 (3), 579-590 (1999)
   PUBMED   10356330
REFERENCE   3  (residues 1 to 447)
  AUTHORS   Bertrand,J.A., Auger,G., Fanchon,E., Martin,L., Blanot,D., van
            Heijenoort,J. and Dideberg,O.
  TITLE     Crystal structure of UDP-N-acetylmuramoyl-L-alanine:D-glutamate
            ligase from Escherichia coli
  JOURNAL   EMBO J 16 (12), 3416-3425 (1997)
   PUBMED   9218784
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01087.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Enterovibrio norvegicus"
                     /db_xref="taxon:188144"
     gene            1..447
                     /gene="murD"
     Protein         1..447
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /EC_number="6.3.2.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /calculated_mol_wt=47168
     Region          4..436
                     /region_name="MurD"
                     /note="UDP-N-acetylmuramoylalanine-D-glutamate ligase
                     [Cell wall/membrane/envelope biogenesis]; COG0771"
                     /db_xref="CDD:440534"
ORIGIN      
        1 mktdaankhi vviglgmtgl svvnhlvakn dgamisvidt rdaapgadkl pqnvalhagg
       61 wnmdwllnad livaspgial aapelkaaaq kgieivgdie lfardvaapv igitgsngks
      121 tvtsllgema kaagvnvgvg gnigfaaldm laydhslyvl elssfqlett ssldmasavf
      181 lnlsedhmdr ydgmedyrqa klrifdqtql alwnqddlqt kapedkyses fgfsqgdytl
      241 tlkegnewlt akgepvmavs dialvgrhnv anclaamala dsvgiardaq cqamreycgl
      301 phrcqqvleh ngilwvndsk atnpastlaa ldglqlpgkl hllvggdgkg aefsslqpvl
      361 aaldvtlycy grdgqafagl vetpvvidtm qqamdiaaqt aksgdmvlls pacasfdqft
      421 nfmvrgetfa ayaqaitahs aletase